8X1N
 
 | | Cryo-EM structure of human alpha-fetoprotein | | Descriptor: | Alpha-fetoprotein, PALMITIC ACID, ZINC ION, ... | | Authors: | Liu, Z.M, Li, M.S, Wu, C, Liu, K. | | Deposit date: | 2023-11-08 | | Release date: | 2024-05-15 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.31 Å) | | Cite: | Structural characteristics of alpha-fetoprotein, including N-glycosylation, metal ion and fatty acid binding sites.
Commun Biol, 7, 2024
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1NYP
 | | 4th LIM domain of PINCH protein | | Descriptor: | PINCH protein, ZINC ION | | Authors: | Velyvis, A, Vaynberg, J, Vinogradova, O, Zhang, Y, Wu, C, Qin, J. | | Deposit date: | 2003-02-13 | | Release date: | 2003-07-01 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structural and functional insights into PINCH LIM4 domain-mediated integrin signaling
Nat.Struct.Biol., 10, 2003
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8F4L
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3HTO
 | | the hemagglutinin structure of an avian H1N1 influenza A virus | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | Authors: | Wang, G, Li, A, Zhang, Q, Wu, C, Zhang, R, Cai, Q, Song, W, Yuen, K.-Y. | | Deposit date: | 2009-06-12 | | Release date: | 2009-08-11 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | The hemagglutinin structure of an avian H1N1 influenza A virus
Virology, 392, 2009
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3HTQ
 | | the hemagglutinin structure of an avian H1N1 influenza A virus in complex with LSTc | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | Authors: | Wang, G, Li, A, Zhang, Q, Wu, C, Zhang, R, Cai, Q, Song, W, Yuen, K.-Y. | | Deposit date: | 2009-06-12 | | Release date: | 2009-08-11 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.955 Å) | | Cite: | The hemagglutinin structure of an avian H1N1 influenza A virus
Virology, 392, 2009
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3HTP
 | | the hemagglutinin structure of an avian H1N1 influenza A virus in complex with LSTa | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | Authors: | Wang, G, Li, A, Zhang, Q, Wu, C, Zhang, R, Cai, Q, Song, W, Yuen, K.-Y. | | Deposit date: | 2009-06-12 | | Release date: | 2009-08-11 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.96 Å) | | Cite: | The hemagglutinin structure of an avian H1N1 influenza A virus
Virology, 392, 2009
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3HTT
 | | The hemagglutinin structure of an avian H1N1 influenza A virus in complex with 2,3-sialyllactose | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | Authors: | Wang, G, Li, A, Zhang, Q, Wu, C, Zhang, R, Cai, Q, Song, W, Yuen, K.-Y. | | Deposit date: | 2009-06-12 | | Release date: | 2009-08-11 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | The hemagglutinin structure of an avian H1N1 influenza A virus
Virology, 392, 2009
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8HI2
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8HHS
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5CHL
 | | Structural basis of H2A.Z recognition by YL1 histone chaperone component of SRCAP/SWR1 chromatin remodeling complex | | Descriptor: | Histone H2A.Z, Vacuolar protein sorting-associated protein 72 homolog | | Authors: | Shan, S, Liang, X, Pan, L, Wu, C, Zhou, Z. | | Deposit date: | 2015-07-10 | | Release date: | 2016-03-09 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.892 Å) | | Cite: | Structural basis of H2A.Z recognition by SRCAP chromatin-remodeling subunit YL1
Nat.Struct.Mol.Biol., 23, 2016
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9IWT
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7FB8
 | | De Novo-Designed and Disulfide-Bridged Peptide Heterodimer - hd1 | | Descriptor: | ASP-ASP-LYS-ASP-CYS-ASP-GLU-TYR-CYS-LYS-LYS-THR-LYS-GLU-NH2, GLU-LE1-THR-GLY-HIS-ILE-GLU-GLY-PRO-THR-LE1-THR-LE1-HIS-CYS-LYS-NH2 | | Authors: | Yao, H, Yao, S, Zheng, Y, Moyer, A, Baker, D, Wu, C. | | Deposit date: | 2021-07-08 | | Release date: | 2022-05-18 | | Last modified: | 2023-11-15 | | Method: | SOLUTION NMR | | Cite: | De novo design and directed folding of disulfide-bridged peptide heterodimers.
Nat Commun, 13, 2022
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7FBA
 | | De Novo-Designed and Disulfide-Bridged Peptide Heterodimer - hd2 | | Descriptor: | ALA-LE1-CYS-GLU-CYS-GLY-PRO-THR-ARG-GLU-CYS-LYS-NH2, GLU-CYS-ARG-GLU-TYR-GLY-PRO-LE1-LYS-LE1-LE1-ALA-NH2 | | Authors: | Yao, H, Yao, S, Moyer, A, Zheng, Y, Baker, D, Wu, C. | | Deposit date: | 2021-07-08 | | Release date: | 2022-05-18 | | Last modified: | 2023-11-15 | | Method: | SOLUTION NMR | | Cite: | De novo design and directed folding of disulfide-bridged peptide heterodimers.
Nat Commun, 13, 2022
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3QBA
 | | Reintroducing Electrostatics into Macromolecular Crystallographic Refinement: Z-DNA (X-ray) | | Descriptor: | Z-DNA | | Authors: | Fenn, T.D, Schnieders, M.J, Mustyakimov, M, Wu, C, Langan, P, Pande, V.S, Brunger, A.T. | | Deposit date: | 2011-01-12 | | Release date: | 2011-03-02 | | Last modified: | 2024-02-21 | | Method: | NEUTRON DIFFRACTION (1.53 Å), X-RAY DIFFRACTION | | Cite: | Reintroducing electrostatics into macromolecular crystallographic refinement: application to neutron crystallography and DNA hydration.
Structure, 19, 2011
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7YIM
 | | Cryo-EM structure of human Alpha-fetoprotein | | Descriptor: | Alpha-fetoprotein | | Authors: | Liu, N, Liu, K, Wu, C, Liu, Z, Li, M, Wang, J, Wang, H.W. | | Deposit date: | 2022-07-17 | | Release date: | 2023-01-18 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Uniform thin ice on ultraflat graphene for high-resolution cryo-EM.
Nat.Methods, 20, 2023
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6KPP
 | | BNC105 in complex with tubulin | | Descriptor: | (6-methoxy-2-methyl-7-oxidanyl-1-benzofuran-3-yl)-(3,4,5-trimethoxyphenyl)methanone, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Wang, T, Wu, C, Pu, D. | | Deposit date: | 2019-08-15 | | Release date: | 2020-08-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.74524117 Å) | | Cite: | Unraveling the molecular mechanism of BNC105, a phase II clinical trial vascular disrupting agent, provides insights into drug design.
Biochem.Biophys.Res.Commun., 2020
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4FVD
 | | Crystal structure of EV71 2A proteinase C110A mutant in complex with substrate | | Descriptor: | 10-mer peptide from 2A proteinase, 2A proteinase, ZINC ION | | Authors: | Cai, Q, Muhammad, Y, Liu, W, Gao, Z, Peng, X, Cai, Y, Wu, C, Zheng, Q, Li, J, Lin, T. | | Deposit date: | 2012-06-29 | | Release date: | 2013-06-19 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Conformational Plasticity of 2A Proteinase from Enterovirus 71
J.Virol., 87, 2013
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4FVB
 | | Crystal structure of EV71 2A proteinase C110A mutant | | Descriptor: | 2A proteinase, ZINC ION | | Authors: | Cai, Q, Muhammad, Y, Liu, W, Gao, Z, Peng, X, Cai, Y, Wu, C, Zheng, Q, Li, J, Lin, T. | | Deposit date: | 2012-06-29 | | Release date: | 2013-06-19 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Conformational Plasticity of 2A Proteinase from Enterovirus 71
J.Virol., 87, 2013
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5VAP
 | | Crystal structure of eVP30 C-terminus and eNP peptide | | Descriptor: | Minor nucleoprotein VP30, NP | | Authors: | XU, W, WU, C, Leung, D.W, Amarasinghe, G.K. | | Deposit date: | 2017-03-27 | | Release date: | 2017-06-21 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis.
Nat Commun, 8, 2017
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7V3P
 | | Cryo-EM structure of the IGF1R/insulin complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ... | | Authors: | Zhang, J, Liu, C, Zhang, X, Wei, T, Wu, C. | | Deposit date: | 2021-08-11 | | Release date: | 2022-08-17 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structure of the IGF1R/insulin complex
To Be Published
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2LAS
 | | Molecular Determinants of Paralogue-Specific SUMO-SIM Recognition | | Descriptor: | M-IR2_peptide, Small ubiquitin-related modifier 1 | | Authors: | Namanja, A, Li, Y, Su, Y, Wong, S, Lu, J, Colson, L, Wu, C, Li, S, Chen, Y. | | Deposit date: | 2011-03-20 | | Release date: | 2011-12-14 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Insights into High Affinity Small Ubiquitin-like Modifier (SUMO) Recognition by SUMO-interacting Motifs (SIMs) Revealed by a Combination of NMR and Peptide Array Analysis.
J.Biol.Chem., 287, 2012
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2L5A
 | | Structural basis for recognition of centromere specific histone H3 variant by nonhistone Scm3 | | Descriptor: | Histone H3-like centromeric protein CSE4, Protein SCM3, Histone H4 | | Authors: | Zhou, Z, Feng, H, Zhou, B, Ghirlando, R, Hu, K, Zwolak, A, Jenkins, L, Xiao, H, Tjandra, N, Wu, C, Bai, Y. | | Deposit date: | 2010-10-28 | | Release date: | 2011-03-16 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3.
Nature, 472, 2011
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8JFY
 | | Cryo-EM structure of RDGC/Ca2+-CaM complex | | Descriptor: | AT15141p, CALCIUM ION, FE (III) ION, ... | | Authors: | Liu, Z.M, Liu, W, Wu, C, Liu, J. | | Deposit date: | 2023-05-19 | | Release date: | 2024-11-27 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | Cryo-EM structure of RDGC/Ca2+-CaM complex
To Be Published
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2K2R
 | | The NMR structure of alpha-parvin CH2/paxillin LD1 complex | | Descriptor: | Alpha-parvin, Paxillin | | Authors: | Wang, X, Fukuda, K, Byeon, I, Velyvis, A, Wu, C, Gronenborn, A, Qin, J. | | Deposit date: | 2008-04-10 | | Release date: | 2008-05-27 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | The Structure of {alpha}-Parvin CH2-Paxillin LD1 Complex Reveals a Novel Modular Recognition for Focal Adhesion Assembly.
J.Biol.Chem., 283, 2008
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2JSS
 | | NMR structure of chaperone Chz1 complexed with histone H2A.Z-H2B | | Descriptor: | Chimera of Histone H2B.1 and Histone H2A.Z, Uncharacterized protein YER030W | | Authors: | Zhou, Z, Feng, H, Hansen, D.F, Kato, H, Luk, E, Freedberg, D.I, Kay, L.E, Wu, C, Bai, Y. | | Deposit date: | 2007-07-11 | | Release date: | 2008-05-20 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B.
Nat.Struct.Mol.Biol., 15, 2008
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