5XS5
 
 | | Structure of Coxsackievirus A6 (CVA6) virus procapsid particle | | Descriptor: | Genome polyprotein | | Authors: | Zheng, Q.B, He, M.Z, Xu, L.F, Yu, H, Cheng, T, Li, S.W. | | Deposit date: | 2017-06-12 | | Release date: | 2017-09-27 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
Nat Commun, 8, 2017
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6MDX
 | | Mechanism of protease dependent DPC repair | | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, DNA (5'-D(P*CP*C)-3'), ... | | Authors: | Li, F, Raczynska, J, Chen, Z, Yu, H. | | Deposit date: | 2018-09-05 | | Release date: | 2019-04-10 | | Last modified: | 2025-04-02 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural Insight into DNA-Dependent Activation of Human Metalloprotease Spartan.
Cell Rep, 26, 2019
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5FBY
 | | Crystal structure of ctSPD | | Descriptor: | cleaved peptide, separase | | Authors: | Lin, Z, Luo, X, Yu, H. | | Deposit date: | 2015-12-14 | | Release date: | 2016-03-30 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.898 Å) | | Cite: | Structural basis of cohesin cleavage by separase.
Nature, 532, 2016
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5FC3
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6OCG
 | | Crystal structure of VASH1-SVBP complex bound with EpoY | | Descriptor: | CHLORIDE ION, GLYCEROL, N-[(3R)-4-ethoxy-3-hydroxy-4-oxobutanoyl]-L-tyrosine, ... | | Authors: | Li, F, Luo, X, Yu, H. | | Deposit date: | 2019-03-23 | | Release date: | 2019-06-26 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.833 Å) | | Cite: | Structural basis of tubulin detyrosination by vasohibins.
Nat.Struct.Mol.Biol., 26, 2019
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5FC2
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7YEH
 | | Cryo-EM structure of human OGT-OGA complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein O-GlcNAcase, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ... | | Authors: | Lu, P, Liu, Y, Yu, H, Gao, H. | | Deposit date: | 2022-07-05 | | Release date: | 2023-07-12 | | Last modified: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.92 Å) | | Cite: | Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex.
Nat Commun, 14, 2023
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4R8Q
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4FTW
 | | Crystal structure of a carboxyl esterase N110C/L145H at 2.3 angstrom resolution | | Descriptor: | 3-CYCLOHEXYLPROPYL 4-O-ALPHA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSIDE, CHLORIDE ION, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID), ... | | Authors: | Wu, L, Ma, J, Zhou, J, Yu, H. | | Deposit date: | 2012-06-28 | | Release date: | 2012-10-03 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution.
Appl.Microbiol.Biotechnol., 97, 2013
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4IW2
 | | HSA-glucose complex | | Descriptor: | D-glucose, PHOSPHATE ION, Serum albumin, ... | | Authors: | Wang, Y, Yu, H, Shi, X, Luo, Z, Huang, M. | | Deposit date: | 2013-01-23 | | Release date: | 2013-04-24 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Structural mechanism of ring-opening reaction of glucose by human serum albumin
J.Biol.Chem., 288, 2013
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4FHZ
 | | Crystal structure of a carboxyl esterase at 2.0 angstrom resolution | | Descriptor: | DI(HYDROXYETHYL)ETHER, Phospholipase/Carboxylesterase, SODIUM ION | | Authors: | Wu, L, Ma, J, Zhou, J, Yu, H. | | Deposit date: | 2012-06-07 | | Release date: | 2012-10-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution.
Appl.Microbiol.Biotechnol., 97, 2013
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4IW1
 | | HSA-fructose complex | | Descriptor: | D-fructose, PHOSPHATE ION, Serum albumin, ... | | Authors: | Wang, Y, Yu, H, Shi, X, Huang, M. | | Deposit date: | 2013-01-23 | | Release date: | 2013-04-24 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Structural mechanism of ring-opening reaction of glucose by human serum albumin
J.Biol.Chem., 288, 2013
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2ESK
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2ESQ
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2ESP
 | | Human ubiquitin-conjugating enzyme (E2) UbcH5b mutant Ile88Ala | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Ubiquitin-conjugating enzyme E2 D2 | | Authors: | Ozkan, E, Yu, H, Deisenhofer, J. | | Deposit date: | 2005-10-26 | | Release date: | 2005-12-06 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2ESO
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5HDT
 | | Human cohesin regulator Pds5B bound to a Wapl peptide | | Descriptor: | INOSITOL HEXAKISPHOSPHATE, Sister chromatid cohesion protein PDS5 homolog B, Wings apart-like protein homolog | | Authors: | Ouyang, Z, Tomchick, D.R, Yu, H. | | Deposit date: | 2016-01-05 | | Release date: | 2016-03-09 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.711 Å) | | Cite: | Structure of the human cohesin regulator Pds5 in complex with Wapl motif
To Be Published
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5JB1
 | | Pseudo-atomic structure of Human Papillomavirus Type 59 L1 Virus-like Particle | | Descriptor: | Major capsid protein L1 | | Authors: | Li, Z.H, Yan, X.D, Yu, H, Zheng, Q.B, Gu, Y, Li, S.W. | | Deposit date: | 2016-04-13 | | Release date: | 2016-05-18 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (6 Å) | | Cite: | The C-Terminal Arm of the Human Papillomavirus Major Capsid Protein Is Immunogenic and Involved in Virus-Host Interaction.
Structure, 24, 2016
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5J6R
 | | Crystal structure of Human Papillomavirus Type 59 L1 pentamer | | Descriptor: | Major capsid protein L1 | | Authors: | Li, Z.H, Yan, X.D, Yu, H, Gu, Y, Li, S.W. | | Deposit date: | 2016-04-05 | | Release date: | 2016-05-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (4.011 Å) | | Cite: | The C-Terminal Arm of the Human Papillomavirus Major Capsid Protein Is Immunogenic and Involved in Virus-Host Interaction.
Structure, 24, 2016
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2IW5
 | | Structural Basis for CoREST-Dependent Demethylation of Nucleosomes by the Human LSD1 Histone Demethylase | | Descriptor: | AMMONIUM ION, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Yang, M, Gocke, C.B, Luo, X, Borek, D, Tomchick, D.R, Machius, M, Otwinowski, Z, Yu, H. | | Deposit date: | 2006-06-26 | | Release date: | 2006-08-09 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.57 Å) | | Cite: | Structural Basis for Corest-Dependent Demethylation of Nucleosomes by the Human Lsd1 Histone Demethylase
Mol.Cell, 23, 2006
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7W1M
 | | Cryo-EM structure of human cohesin-CTCF-DNA complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cohesin subunit SA-1, ... | | Authors: | Shi, Z.B, Bai, X.C, Yu, H. | | Deposit date: | 2021-11-19 | | Release date: | 2023-05-31 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (6.5 Å) | | Cite: | CTCF and R-loops are boundaries of cohesin-mediated DNA looping.
Mol.Cell, 83, 2023
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7VCU
 | | Human p97 double hexamer conformer I with D1-ATPgammaS and D2-ADP bound | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | | Deposit date: | 2021-09-04 | | Release date: | 2022-03-02 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
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7VCX
 | | Human p97 single hexamer conformer II with ATPgammaS bound | | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | | Authors: | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | | Deposit date: | 2021-09-04 | | Release date: | 2022-03-02 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
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7VCT
 | | Human p97 single hexamer conformer III with D1-ATPgammaS and D2-ADP bound | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | | Deposit date: | 2021-09-04 | | Release date: | 2022-03-02 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.21 Å) | | Cite: | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
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7VCS
 | | Human p97 double hexamer conformer II with ATPgammaS bound | | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | | Authors: | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | | Deposit date: | 2021-09-03 | | Release date: | 2022-03-02 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
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