3U88
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3u88 by Molmil](/molmil-images/mine/3u88) | Crystal structure of human menin in complex with MLL1 and LEDGF | Descriptor: | (4beta,8alpha,9R)-6'-methoxy-10,11-dihydrocinchonan-9-ol, CHOLIC ACID, GLYOXYLIC ACID, ... | Authors: | Huang, J, Wan, B, Lei, M. | Deposit date: | 2011-10-16 | Release date: | 2012-02-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature, 482, 2012
|
|
3U84
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3u84 by Molmil](/molmil-images/mine/3u84) | Crystal Structure of Human Menin | Descriptor: | Menin | Authors: | Huang, J, Wan, B, Lei, M. | Deposit date: | 2011-10-15 | Release date: | 2012-02-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature, 482, 2012
|
|
3TOJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3toj by Molmil](/molmil-images/mine/3toj) | Structure of the SPRY domain of human Ash2L | Descriptor: | Set1/Ash2 histone methyltransferase complex subunit ASH2 | Authors: | Chen, Y, Cao, F, Wan, B, Dou, Y, Lei, M. | Deposit date: | 2011-09-05 | Release date: | 2012-01-25 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30. Cell Res., 22, 2012
|
|
3HEI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hei by Molmil](/molmil-images/mine/3hei) | Ligand Recognition by A-Class Eph Receptors: Crystal Structures of the EphA2 Ligand-Binding Domain and the EphA2/ephrin-A1 Complex | Descriptor: | Ephrin type-A receptor 2, Ephrin-A1 | Authors: | Himanen, J.P, Goldgur, Y, Miao, H, Myshkin, E, Guo, H, Buck, M, Nguyen, M, Rajashankar, K.R, Wang, B, Nikolov, D.B. | Deposit date: | 2009-05-08 | Release date: | 2009-06-30 | Last modified: | 2021-03-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex. Embo Rep., 10, 2009
|
|
4O63
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o63 by Molmil](/molmil-images/mine/4o63) | Co-enzyme Induced Conformational Changes in Bovine Eye Glyceraldehyde 3-Phosphate Dehydrogenase | Descriptor: | Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Baker, B.Y, Shi, W, Wang, B, Palczewski, K. | Deposit date: | 2013-12-20 | Release date: | 2014-09-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules. Protein Sci., 23, 2014
|
|
7M1S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7m1s by Molmil](/molmil-images/mine/7m1s) | |
1A37
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1a37 by Molmil](/molmil-images/mine/1a37) | 14-3-3 PROTEIN ZETA BOUND TO PS-RAF259 PEPTIDE | Descriptor: | 14-3-3 PROTEIN ZETA, PS-RAF259 PEPTIDE LSQRQRST(SEP)TPNVHM | Authors: | Petosa, C, Masters, S.C, Pohl, J, Wang, B, Fu, H, Liddington, R.C. | Deposit date: | 1998-01-28 | Release date: | 1999-03-02 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | 14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove. J.Biol.Chem., 273, 1998
|
|
4AOJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4aoj by Molmil](/molmil-images/mine/4aoj) | Human TrkA in complex with the inhibitor AZ-23 | Descriptor: | 5-chloranyl-N2-[(1S)-1-(5-fluoranylpyridin-2-yl)ethyl]-N4-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyrimidine-2,4-diamine, HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR, ZINC ION | Authors: | Wang, T, Lamb, M.L, Block, M.H, Davies, A.M, Han, Y, Hoffmann, E, Ioannidis, S, Josey, J.A, Liu, Z, Lyne, P.D, MacIntyre, T, Mohr, P.J, Omer, C.A, Sjogren, T, Thress, K, Wang, B, Wang, H, Yu, D, Zhang, H. | Deposit date: | 2012-03-28 | Release date: | 2012-08-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Discovery of Disubstituted Imidazo[4,5-B]Pyridines and Purines as Potent Trka Inhibitors Acs Med.Chem.Lett., 3, 2012
|
|
1A38
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1a38 by Molmil](/molmil-images/mine/1a38) | 14-3-3 PROTEIN ZETA BOUND TO R18 PEPTIDE | Descriptor: | 14-3-3 PROTEIN ZETA, R18 PEPTIDE (PHCVPRDLSWLDLEANMCLP) | Authors: | Petosa, C, Masters, S.C, Pohl, J, Wang, B, Fu, H, Liddington, R.C. | Deposit date: | 1998-01-28 | Release date: | 1999-03-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | 14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove. J.Biol.Chem., 273, 1998
|
|
3ID2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3id2 by Molmil](/molmil-images/mine/3id2) | Crystal Structure of RseP PDZ2 domain | Descriptor: | IODIDE ION, Regulator of sigma E protease | Authors: | Li, X, Wang, B, Feng, L, Wang, J, Shi, Y. | Deposit date: | 2009-07-20 | Release date: | 2009-08-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.089 Å) | Cite: | Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
3ID4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3id4 by Molmil](/molmil-images/mine/3id4) | Crystal Structure of RseP PDZ2 domain fused GKASPV peptide | Descriptor: | Regulator of sigma E protease | Authors: | Li, X, Wang, B, Feng, L, Wang, J, Shi, Y. | Deposit date: | 2009-07-20 | Release date: | 2009-08-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.604 Å) | Cite: | Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
3ID1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3id1 by Molmil](/molmil-images/mine/3id1) | Crystal Structure of RseP PDZ1 domain | Descriptor: | Regulator of sigma E protease | Authors: | Li, X, Wang, B, Feng, L, Wang, J, Shi, Y. | Deposit date: | 2009-07-20 | Release date: | 2009-08-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
3ID3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3id3 by Molmil](/molmil-images/mine/3id3) | Crystal Structure of RseP PDZ2 I304A domain | Descriptor: | Regulator of sigma E protease | Authors: | Li, X, Wang, B, Feng, L, Wang, J, Shi, Y. | Deposit date: | 2009-07-20 | Release date: | 2009-08-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
6SX6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6sx6 by Molmil](/molmil-images/mine/6sx6) | Guanine-rich oligonucleotide with 5'-GC end form G-quadruplex with A(GGGG)A hexad, GCGC- and G-quartets and two symmetric GG and AA base pairs | Descriptor: | GCn | Authors: | Pavc, D, Wang, B, Spindler, L, Drevensek-Olenik, I, Plavec, J, Sket, P. | Deposit date: | 2019-09-25 | Release date: | 2020-07-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | GC ends control topology of DNA G-quadruplexes and their cation-dependent assembly. Nucleic Acids Res., 48, 2020
|
|
6SYK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6syk by Molmil](/molmil-images/mine/6syk) | Guanine-rich oligonucleotide with 5'- and 3'-GC ends form G-quadruplex with A(GGGG)A hexad, GCGC- and G-quartets and two symmetric GG and AA base pair | Descriptor: | GCnCG | Authors: | Pavc, D, Wang, B, Spindler, L, Drevensek-Olenik, I, Plavec, J, Sket, P. | Deposit date: | 2019-09-30 | Release date: | 2020-07-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | GC ends control topology of DNA G-quadruplexes and their cation-dependent assembly. Nucleic Acids Res., 48, 2020
|
|
8FDJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fdj by Molmil](/molmil-images/mine/8fdj) | Wild-Type Sperm Whale Myoglobin in Complex with Nitrosobenzene | Descriptor: | Myoglobin, NITROSOBENZENE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Powell, S.M, Wang, B, Thomas, L.M, Richter-Addo, G.B. | Deposit date: | 2022-12-03 | Release date: | 2023-07-12 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structural investigations of heme protein derivatives resulting from reactions of aryl- and alkylhydroxylamines with human hemoglobin. J.Inorg.Biochem., 246, 2023
|
|
5LQG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lqg by Molmil](/molmil-images/mine/5lqg) | |
5LIG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lig by Molmil](/molmil-images/mine/5lig) | G-Quadruplex formed at the 5'-end of NHEIII_1 Element in human c-MYC promoter bound to triangulenium based fluorescence probe DAOTA-M2 | Descriptor: | 8,12-bis(2-morpholinoethyl)-8H-benzo[ij]xantheno[1,9,8-cdef][2,7]naphthyridin-12-iumhexafluorophosphate, DNA (5'-D(*TP*AP*GP*GP*GP*AP*GP*GP*GP*TP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3') | Authors: | Kotar, A, Wang, B, Shivalingam, A, Gonzalez-Garcia, J, Vilar, R, Plavec, J. | Deposit date: | 2016-07-14 | Release date: | 2016-09-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR Structure of a Triangulenium-Based Long-Lived Fluorescence Probe Bound to a G-Quadruplex. Angew.Chem.Int.Ed.Engl., 55, 2016
|
|
5LQH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lqh by Molmil](/molmil-images/mine/5lqh) | |
6OTT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ott by Molmil](/molmil-images/mine/6ott) | Structure of PurF in complex with ppApp | Descriptor: | Amidophosphoribosyltransferase, PurF, MAGNESIUM ION, ... | Authors: | Grant, R.A, Wang, B, Laub, M.T. | Deposit date: | 2019-05-03 | Release date: | 2019-11-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp. Nature, 575, 2019
|
|
7MJV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mjv by Molmil](/molmil-images/mine/7mjv) | MiaB in the complex with s-adenosylmethionine and RNA | Descriptor: | FE3-S4 CLUSTER, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | Authors: | Esakova, O.A, Grove, T.L, Yennawar, N.H, Arcinas, A.J, Wang, B, Krebs, C, Almo, S.C, Booker, S.J. | Deposit date: | 2021-04-20 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB. Nature, 597, 2021
|
|
7MJY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mjy by Molmil](/molmil-images/mine/7mjy) | MiaB in the complex with s-adenosyl-L-homocysteine and RNA | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FE3-S4 CLUSTER, ... | Authors: | Esakova, O.A, Grove, T.L, Yennawar, N.H, Arcinas, A.J, Wang, B, Krebs, C, Almo, S.C, Booker, S.J. | Deposit date: | 2021-04-20 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB. Nature, 597, 2021
|
|
7MJZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mjz by Molmil](/molmil-images/mine/7mjz) | The structure of MiaB with pentasulfide bridge | Descriptor: | IRON/SULFUR CLUSTER, PENTASULFIDE-SULFUR, SODIUM ION, ... | Authors: | Esakova, O.A, Grove, T.L, Yennawar, N.H, Arcinas, A.J, Wang, B, Krebs, C, Almo, S.C, Booker, S.J. | Deposit date: | 2021-04-20 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB. Nature, 597, 2021
|
|
7MJW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mjw by Molmil](/molmil-images/mine/7mjw) | Methylated MiaB in the complex with 5'-deoxyadenosine, methionine and RNA | Descriptor: | 5'-DEOXYADENOSINE, FE3-S4 methylated cluster, IRON/SULFUR CLUSTER, ... | Authors: | Esakova, O.A, Grove, T.L, Yennawar, N.H, Arcinas, A.J, Wang, B, Krebs, C, Almo, S.C, Booker, S.J. | Deposit date: | 2021-04-20 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB. Nature, 597, 2021
|
|
7MJX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mjx by Molmil](/molmil-images/mine/7mjx) | MiaB in the complex with 5'-deoxyadenosine, methionine and RNA | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-DEOXYADENOSINE, FE3-S4 CLUSTER, ... | Authors: | Esakova, O.A, Grove, T.L, Yennawar, N.H, Arcinas, A.J, Wang, B, Krebs, C, Almo, S.C, Booker, S.J. | Deposit date: | 2021-04-20 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB. Nature, 597, 2021
|
|