5LIG
G-Quadruplex formed at the 5'-end of NHEIII_1 Element in human c-MYC promoter bound to triangulenium based fluorescence probe DAOTA-M2
Summary for 5LIG
Entry DOI | 10.2210/pdb5lig/pdb |
NMR Information | BMRB: 34025 |
Descriptor | DNA (5'-D(*TP*AP*GP*GP*GP*AP*GP*GP*GP*TP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3'), 8,12-bis(2-morpholinoethyl)-8H-benzo[ij]xantheno[1,9,8-cdef][2,7]naphthyridin-12-iumhexafluorophosphate (2 entities in total) |
Functional Keywords | dna, g-quadruplex, c-myc promoter, ligand, daota-m2 |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 7092.17 |
Authors | Kotar, A.,Wang, B.,Shivalingam, A.,Gonzalez-Garcia, J.,Vilar, R.,Plavec, J. (deposition date: 2016-07-14, release date: 2016-09-14, Last modification date: 2024-05-15) |
Primary citation | Kotar, A.,Wang, B.,Shivalingam, A.,Gonzalez-Garcia, J.,Vilar, R.,Plavec, J. NMR Structure of a Triangulenium-Based Long-Lived Fluorescence Probe Bound to a G-Quadruplex. Angew.Chem.Int.Ed.Engl., 55:12508-12511, 2016 Cited by PubMed: 27577037DOI: 10.1002/anie.201606877 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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