8JJK
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![BU of 8jjk by Molmil](/molmil-images/mine/8jjk) | SP1746 in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, FE (III) ION, GLYCEROL, ... | Authors: | Jin, Y, Niu, L, Ke, J. | Deposit date: | 2023-05-30 | Release date: | 2024-05-08 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia. Structure, 2024
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8JKP
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![BU of 8jkp by Molmil](/molmil-images/mine/8jkp) | SP1746 in complex with dTMP | Descriptor: | FE (III) ION, GLYCEROL, SULFATE ION, ... | Authors: | Jin, Y, Ke, J, Niu, L. | Deposit date: | 2023-06-01 | Release date: | 2024-05-08 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia. Structure, 2024
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8JKR
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![BU of 8jkr by Molmil](/molmil-images/mine/8jkr) | SP1746 in complex with UMP | Descriptor: | 1,2-ETHANEDIOL, FE (III) ION, GLYCEROL, ... | Authors: | Jin, Y, Niu, L, Ke, J. | Deposit date: | 2023-06-01 | Release date: | 2024-05-08 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia. Structure, 2024
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8JK5
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![BU of 8jk5 by Molmil](/molmil-images/mine/8jk5) | |
8JK9
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![BU of 8jk9 by Molmil](/molmil-images/mine/8jk9) | SP1746 in complex with GDP | Descriptor: | FE (III) ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Jin, Y, Ke, J, Niu, L. | Deposit date: | 2023-06-01 | Release date: | 2024-05-08 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia. Structure, 2024
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8JJA
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![BU of 8jja by Molmil](/molmil-images/mine/8jja) | SP1746 in complex with acetate ions | Descriptor: | ACETATE ION, FE (III) ION, bis(5'-nucleosyl)-tetraphosphatase (symmetrical) | Authors: | Jin, Y, Niu, L, Ke, J. | Deposit date: | 2023-05-30 | Release date: | 2024-05-08 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia. Structure, 2024
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8JK8
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![BU of 8jk8 by Molmil](/molmil-images/mine/8jk8) | SP1746 in complex with UDP | Descriptor: | 1,2-ETHANEDIOL, FE (III) ION, GLYCEROL, ... | Authors: | Jin, Y, Niu, L, Ke, J. | Deposit date: | 2023-06-01 | Release date: | 2024-05-08 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia. Structure, 2024
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6IEX
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![BU of 6iex by Molmil](/molmil-images/mine/6iex) | Crystal structure of HLA-B*4001 in complex with SARS-CoV derived peptide N216-225 GETALALLLL | Descriptor: | Beta-2-microglobulin, GLY-GLU-THR-ALA-LEU-ALA-LEU-LEU-LEU-LEU, MHC class I antigen | Authors: | Ji, W, Niu, L, Peng, W, Zhang, Y, Shi, Y, Qi, J, Gao, G.F, Liu, W.J. | Deposit date: | 2018-09-17 | Release date: | 2019-09-18 | Last modified: | 2021-03-31 | Method: | X-RAY DIFFRACTION (2.314 Å) | Cite: | Salt bridge-forming residues positioned over viral peptides presented by MHC class I impacts T-cell recognition in a binding-dependent manner. Mol.Immunol., 112, 2019
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4HG5
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![BU of 4hg5 by Molmil](/molmil-images/mine/4hg5) | Structural insights into yeast Nit2: wild-type yeast Nit2 in complex with oxaloacetate | Descriptor: | CACODYLATE ION, GLYCEROL, OXALOACETATE ION, ... | Authors: | Liu, H, Qiu, X, Zhang, M, Gao, Y, Niu, L, Teng, M. | Deposit date: | 2012-10-07 | Release date: | 2013-07-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2 Acta Crystallogr.,Sect.D, 69, 2013
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4HGD
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![BU of 4hgd by Molmil](/molmil-images/mine/4hgd) | Structural insights into yeast Nit2: C169S mutant of yeast Nit2 in complex with an endogenous peptide-like ligand | Descriptor: | CACODYLATE ION, GLYCEROL, N-(4-carboxy-4-oxobutanoyl)-L-cysteinylglycine, ... | Authors: | Liu, H, Qiu, X, Zhang, M, Gao, Y, Niu, L, Teng, M. | Deposit date: | 2012-10-08 | Release date: | 2013-07-31 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2 Acta Crystallogr.,Sect.D, 69, 2013
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4HG3
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![BU of 4hg3 by Molmil](/molmil-images/mine/4hg3) | Structural insights into yeast Nit2: wild-type yeast Nit2 in complex with alpha-ketoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, CACODYLATE ION, GLYCEROL, ... | Authors: | Liu, H, Qiu, X, Zhang, M, Gao, Y, Niu, L, Teng, M. | Deposit date: | 2012-10-06 | Release date: | 2013-07-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2 Acta Crystallogr.,Sect.D, 69, 2013
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4H0S
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4H5U
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![BU of 4h5u by Molmil](/molmil-images/mine/4h5u) | Structural insights into yeast Nit2: wild-type yeast Nit2 | Descriptor: | CACODYLATE ION, GLYCEROL, Probable hydrolase NIT2 | Authors: | Liu, H, Qiu, X, Zhang, M, Gao, Y, Niu, L, Teng, M. | Deposit date: | 2012-09-18 | Release date: | 2013-07-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2 Acta Crystallogr.,Sect.D, 69, 2013
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4HG9
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![BU of 4hg9 by Molmil](/molmil-images/mine/4hg9) | Crystal structure of AhV_bPA, a basic PLA2 from Agkistrodon halys pallas venom | Descriptor: | Basic phospholipase A2 B, CALCIUM ION, CITRIC ACID, ... | Authors: | Zeng, F, Niu, L, Li, X, Teng, M. | Deposit date: | 2012-10-07 | Release date: | 2012-10-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of AhV_bPA, a basic PLA2 from Agkistrodon halys pallas venom TO BE PUBLISHED
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4KEG
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![BU of 4keg by Molmil](/molmil-images/mine/4keg) | Crystal Structure of MBP Fused Human SPLUNC1 | Descriptor: | MAGNESIUM ION, Maltose-binding periplasmic/Palate lung and nasal epithelium clone fusion protein, octyl beta-D-glucopyranoside | Authors: | Ning, F, Wang, C, Niu, L, Chu, H.W, Zhang, G. | Deposit date: | 2013-04-25 | Release date: | 2014-04-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Lipid Ligands of the SPLUNC1 Protein To be Published
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5XLT
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![BU of 5xlt by Molmil](/molmil-images/mine/5xlt) | The crystal structure of tubulin in complex with 4'-demethylepipodophyllotoxin | Descriptor: | (5S,5aR,8aR,9R)-9-(3,5-dimethoxy-4-oxidanyl-phenyl)-5-oxidanyl-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Yu, Y, Chen, Q. | Deposit date: | 2017-05-11 | Release date: | 2017-09-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.813 Å) | Cite: | Structure of 4'-demethylepipodophyllotoxin in complex with tubulin provides a rationale for drug design Biochem. Biophys. Res. Commun., 493, 2017
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6KNZ
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![BU of 6knz by Molmil](/molmil-images/mine/6knz) | Crystal structure of T2R-TTL-KXO1 complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[5-[4-(2-morpholin-4-ylethoxy)phenyl]pyridin-2-yl]-~{N}-(phenylmethyl)ethanamide, CALCIUM ION, ... | Authors: | Chen, Q, Yu, Y. | Deposit date: | 2019-08-07 | Release date: | 2019-10-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.475 Å) | Cite: | Reversible binding of the anticancer drug KXO1 (tirbanibulin) to the colchicine-binding site of beta-tubulin explains KXO1's low clinical toxicity. J.Biol.Chem., 294, 2019
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6L8F
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6L8E
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![BU of 6l8e by Molmil](/molmil-images/mine/6l8e) | Crystal structure of heterohexameric YoeB-YefM complex bound to 26bp-DNA | Descriptor: | DNA (26-mer), YefM Antitoxin, YoeB toxin | Authors: | Yue, J, Xue, L. | Deposit date: | 2019-11-06 | Release date: | 2020-09-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Distinct oligomeric structures of the YoeB-YefM complex provide insights into the conditional cooperativity of type II toxin-antitoxin system. Nucleic Acids Res., 48, 2020
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7DP8
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![BU of 7dp8 by Molmil](/molmil-images/mine/7dp8) | Crystal structure of T2R-TTL-Cevipabulin-eribulin complex | Descriptor: | (1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,33R,35R,36S)-20-[(2S)-3-amino-2-hydroxypropyl]-21-methoxy-14-methyl-8,15-dimethylidene-2,19,30,34,37,39,40,41-octaoxanonacyclo[24.9.2.1~3,32~.1~3,33~.1~6,9~.1~12,16~.0~18,22~.0~29,36~.0~31,35~]hentetracontan-24-one (non-preferred name), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-[2,6-bis(fluoranyl)-4-[3-(methylamino)propoxy]phenyl]-5-chloranyl-N-[(2S)-1,1,1-tris(fluoranyl)propan-2-yl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine, ... | Authors: | Chen, L.J, Chen, Q, Yu, Y, Yang, J.H. | Deposit date: | 2020-12-18 | Release date: | 2021-07-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.446 Å) | Cite: | Cevipabulin-tubulin complex reveals a novel agent binding site on alpha-tubulin with tubulin degradation effect. Sci Adv, 7, 2021
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7DSJ
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![BU of 7dsj by Molmil](/molmil-images/mine/7dsj) | |
7DSM
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7DSO
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![BU of 7dso by Molmil](/molmil-images/mine/7dso) | |
7DSR
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![BU of 7dsr by Molmil](/molmil-images/mine/7dsr) | |
7DSP
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![BU of 7dsp by Molmil](/molmil-images/mine/7dsp) | |