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2K86
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BU of 2k86 by Molmil
Solution Structure of FOXO3a Forkhead domain
Descriptor: Forkhead box protein O3
Authors:Wang, F, Marshall, C.B, Li, G, Plevin, M.J, Ikura, M.
Deposit date:2008-09-02
Release date:2008-10-14
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Biochemical and structural characterization of an intramolecular interaction in FOXO3a and its binding with p53.
J.Mol.Biol., 384, 2008
2H7B
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BU of 2h7b by Molmil
Solution structure of the eTAFH domain from the human leukemia-associated fusion protein AML1-ETO
Descriptor: Core-binding factor, ML1-ETO
Authors:Plevin, M.J, Zhang, J, Guo, C, Roeder, R.G, Ikura, M.
Deposit date:2006-06-01
Release date:2006-07-11
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain
Proc.Natl.Acad.Sci.USA, 103, 2006
2HQH
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BU of 2hqh by Molmil
Crystal structure of p150Glued and CLIP-170
Descriptor: Dynactin-1, Restin, ZINC ION
Authors:Hayashi, I, Ikura, M.
Deposit date:2006-07-18
Release date:2007-08-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:CLIP170 autoinhibition mimics intermolecular interactions with p150Glued or EB1.
Nat.Struct.Mol.Biol., 14, 2007
2K60
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BU of 2k60 by Molmil
NMR structure of calcium-loaded STIM1 EF-SAM
Descriptor: CALCIUM ION, PROTEIN (Stromal interaction molecule 1)
Authors:Stathopulos, P.B, Ikura, M.
Deposit date:2008-07-02
Release date:2008-10-07
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry.
Cell(Cambridge,Mass.), 135, 2008
2KWF
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BU of 2kwf by Molmil
The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1
Descriptor: CREB-binding protein, Transcription factor 4
Authors:Denis, C.M, Chitayat, S, Plevin, M.J, Liu, S, Spencer, H.L, Ikura, M, LeBrun, D.P, Smith, S.P.
Deposit date:2010-04-08
Release date:2011-07-20
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1
To be Published
5Y0C
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BU of 5y0c by Molmil
Crystal Structure of the human nucleosome at 2.09 angstrom resolution
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
Authors:Kurumizaka, H, Arimura, Y, Fujita, R, Noda, M.
Deposit date:2017-07-16
Release date:2018-07-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.087 Å)
Cite:Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
Nucleic Acids Res., 46, 2018
5Y0D
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BU of 5y0d by Molmil
Crystal Structure of the human nucleosome containing the H2B E76K mutant
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
Authors:Kurumizaka, H, Arimura, Y, Fujita, R, Noda, M.
Deposit date:2017-07-16
Release date:2018-07-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
Nucleic Acids Res., 46, 2018
5Z30
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BU of 5z30 by Molmil
The crystal structure of the nucleosome containing a cancer-associated histone H2A.Z R80C mutant
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A.Z, ...
Authors:Horikoshi, N, Arimura, Y, Kurumizaka, H.
Deposit date:2018-01-05
Release date:2018-07-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
Nucleic Acids Res., 46, 2018
5E95
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BU of 5e95 by Molmil
Crystal Structure of Mb(NS1)/H-Ras Complex
Descriptor: GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Eguchi, R.R, Sha, F, Gupta, A, Koide, A, Koide, S.
Deposit date:2015-10-14
Release date:2016-11-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.402 Å)
Cite:Inhibition of RAS function through targeting an allosteric regulatory site.
Nat. Chem. Biol., 13, 2017
3RQR
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BU of 3rqr by Molmil
Crystal structure of the RYR domain of the rabbit ryanodine receptor
Descriptor: (UNK)(UNK)(UNK)(UNK), Ryanodine receptor 1
Authors:Nair, U.B, Li, W, Dong, A, Walker, J.R, Gramolini, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2011-04-28
Release date:2011-06-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural determination of the phosphorylation domain of the ryanodine receptor.
Febs J., 279, 2012
4KEI
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BU of 4kei by Molmil
Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S
Descriptor: Ryanodine receptor 2
Authors:Kimlicka, L, Van Petegem, F.
Deposit date:2013-04-25
Release date:2013-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013
4KEK
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BU of 4kek by Molmil
Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant R176Q
Descriptor: Ryanodine receptor 2, SULFATE ION
Authors:Kimlicka, L, Van Petegem, F.
Deposit date:2013-04-25
Release date:2013-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.146 Å)
Cite:Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013
4KEJ
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BU of 4kej by Molmil
Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant R169Q
Descriptor: Ryanodine receptor 2
Authors:Kimlicka, L, Van Petegem, F.
Deposit date:2013-04-25
Release date:2013-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.553 Å)
Cite:Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013
7JIF
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BU of 7jif by Molmil
HRAS A59T GppNHp
Descriptor: GLYCEROL, GTPase HRas, MAGNESIUM ION, ...
Authors:Johnson, C.W, Haigis, K.M.
Deposit date:2020-07-23
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.757 Å)
Cite:Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
7JII
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BU of 7jii by Molmil
HRAS A59E GDP
Descriptor: CALCIUM ION, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Johnson, C.W, Haigis, K.M.
Deposit date:2020-07-23
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.532 Å)
Cite:Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
7JIH
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BU of 7jih by Molmil
HRAS A59E GppNHp
Descriptor: GLYCEROL, GTPase HRas, MAGNESIUM ION, ...
Authors:Johnson, C.W, Haigis, K.M.
Deposit date:2020-07-23
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.989 Å)
Cite:Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
7JIG
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BU of 7jig by Molmil
HRAS A59T GppNHp crystal 2
Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Johnson, C.W, Haigis, K.M.
Deposit date:2020-07-23
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.322 Å)
Cite:Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
7KMR
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BU of 7kmr by Molmil
Crystal structure analysis of human KRAS mutant
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas
Authors:Seo, H.-S, Dhe-Paganon, S.
Deposit date:2020-11-03
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
2Z6Y
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BU of 2z6y by Molmil
Crystal structure of a photoswitchable GFP-like protein Dronpa in the bright-state
Descriptor: Fluorescent protein Dronpa
Authors:Kikuchi, A, Jeyakanthan, J, Taka, J, Shiro, Y, Mizuno, H, Miyawaki, A.
Deposit date:2007-08-09
Release date:2008-07-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Light-dependent regulation of structural flexibility in a photochromic fluorescent protein.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2Z6Z
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BU of 2z6z by Molmil
Crystal structure of a photoswitchable GFP-like protein Dronpa in the bright-state
Descriptor: Fluorescent protein Dronpa
Authors:Kikuchi, A, Jeyakanthan, J, Taka, J, Shiro, Y, Mizuno, H, Miyawaki, A.
Deposit date:2007-08-09
Release date:2008-07-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Light-dependent regulation of structural flexibility in a photochromic fluorescent protein.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2Z1O
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BU of 2z1o by Molmil
Crystal structure of a photoswitchable GFP-like protein Dronpa in the bright-state
Descriptor: Fluorescent protein Dronpa
Authors:Kikuchi, A, Jeyakanthan, J, Taka, J, Shiro, Y, Mizuno, H, Miyawaki, A.
Deposit date:2007-05-10
Release date:2008-05-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Light-dependent regulation of structural flexibility in a photochromic fluorescent protein
Proc.Natl.Acad.Sci.Usa, 105, 2008
2Z6X
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BU of 2z6x by Molmil
Crystal structure of 22G, the wild-type protein of the photoswitchable GFP-like protein Dronpa
Descriptor: photochromic protein Dronpa
Authors:Kikuchi, A, Jeyakanthan, J, Taka, J, Shiro, Y, Mizuno, H, Miyawaki, A.
Deposit date:2007-08-09
Release date:2008-07-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Light-dependent regulation of structural flexibility in a photochromic fluorescent protein.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1NPS
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BU of 1nps by Molmil
CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF PROTEIN S
Descriptor: CALCIUM ION, DEVELOPMENT-SPECIFIC PROTEIN S
Authors:Wenk, M, Baumgartner, R, Mayer, E.M, Huber, R, Holak, T.A, Jaenicke, R.
Deposit date:1999-02-01
Release date:2000-02-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The domains of protein S from Myxococcus xanthus: structure, stability and interactions.
J.Mol.Biol., 286, 1999
1C9B
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BU of 1c9b by Molmil
CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)
Descriptor: ADMLP TATA-BOX DNA CONTAINING IIB RECOGNITION ELEMENT, GENERAL TRANSCRIPTION FACTOR IIB, TATA BOX BINDING PROTEIN
Authors:Tsai, F.T.F, Sigler, P.B.
Deposit date:1999-08-01
Release date:2000-01-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis of preinitiation complex assembly on human pol II promoters.
EMBO J., 19, 2000
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