8QZ9
 
 | | Human 20S proteasome assembly intermediate structure 4 | | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | | Deposit date: | 2023-10-26 | | Release date: | 2024-02-21 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 31, 2024
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8QYL
 | | Human 20S proteasome assembly intermediate structure 2 | | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | | Deposit date: | 2023-10-26 | | Release date: | 2024-02-21 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.67 Å) | | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 31, 2024
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8QYM
 | | Human 20S proteasome assembly intermediate structure 3 | | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | | Deposit date: | 2023-10-26 | | Release date: | 2024-02-21 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (2.73 Å) | | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 31, 2024
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8QYS
 | | Human preholo proteasome 20S core particle | | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | | Deposit date: | 2023-10-26 | | Release date: | 2024-02-21 | | Last modified: | 2024-08-28 | | Method: | ELECTRON MICROSCOPY (3.89 Å) | | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 31, 2024
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8QYN
 | | Human 20S proteasome assembly intermediate structure 5 | | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | | Deposit date: | 2023-10-26 | | Release date: | 2024-02-21 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.88 Å) | | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 31, 2024
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2F5K
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7OSG
 | | ABC Transporter complex NosDFYL, consensus refinement | | Descriptor: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | | Authors: | Mueller, C, Zhang, L, Lu, W, Du, J, Einsle, O. | | Deposit date: | 2021-06-08 | | Release date: | 2022-06-22 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase.
Nature, 608, 2022
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7OSH
 | | ABC Transporter complex NosDFYL, R-domain 2 | | Descriptor: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | | Authors: | Mueller, C, Zhang, L, Lu, W, Du, J, Einsle, O. | | Deposit date: | 2021-06-08 | | Release date: | 2022-06-22 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase.
Nature, 608, 2022
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7OSJ
 | | ABC Transporter complex NosDFYL, membrane anchor | | Descriptor: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | | Authors: | Mueller, C, Zhang, L, Lu, W, Du, J, Einsle, O. | | Deposit date: | 2021-06-08 | | Release date: | 2022-06-22 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase.
Nature, 608, 2022
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7OSI
 | | ABC Transporter complex NosDFYL, R-domain 3 | | Descriptor: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | | Authors: | Mueller, C, Zhang, L, Lu, W, Du, J, Einsle, O. | | Deposit date: | 2021-06-08 | | Release date: | 2022-06-22 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase.
Nature, 608, 2022
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7OSF
 | | ABC Transporter complex NosDFYL, R-domain 1 | | Descriptor: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | | Authors: | Mueller, C, Zhang, L, Lu, W, Du, J, Einsle, O. | | Deposit date: | 2021-06-08 | | Release date: | 2022-06-22 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase.
Nature, 608, 2022
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6LQE
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6LQF
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5ZWZ
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5ZWX
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7JNA
 | | Cryo-EM structure of human proton-activated chloride channel PAC at pH 8 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Proton-activated chloride channel | | Authors: | Lu, W, Ruan, R, Du, J. | | Deposit date: | 2020-08-04 | | Release date: | 2020-11-11 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structures and pH-sensing mechanism of the proton-activated chloride channel.
Nature, 588, 2020
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7JNC
 | | cryo-EM structure of human proton-activated chloride channel PAC at pH 4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Proton-activated chloride channel | | Authors: | Lu, W, Ruan, R, Du, J. | | Deposit date: | 2020-08-04 | | Release date: | 2020-11-11 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.73 Å) | | Cite: | Structures and pH-sensing mechanism of the proton-activated chloride channel.
Nature, 588, 2020
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8SR9
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium | | Descriptor: | CHOLESTEROL, MAGNESIUM ION, TRPM2 chanzyme | | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | | Deposit date: | 2023-05-05 | | Release date: | 2024-05-08 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
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8SR8
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of EDTA (apo state) | | Descriptor: | CHOLESTEROL, TRPM2 chanzyme | | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | | Deposit date: | 2023-05-05 | | Release date: | 2024-05-08 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.77 Å) | | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
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8SRA
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium | | Descriptor: | CALCIUM ION, CHOLESTEROL, TRPM2 chanzyme | | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | | Deposit date: | 2023-05-05 | | Release date: | 2024-05-08 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
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8SRC
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium and ADP-ribose | | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, CHOLESTEROL, ... | | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | | Deposit date: | 2023-05-05 | | Release date: | 2024-05-08 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
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8SR7
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and Ribose-5-phosphate | | Descriptor: | 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, CHOLESTEROL, ... | | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | | Deposit date: | 2023-05-05 | | Release date: | 2024-05-08 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (1.97 Å) | | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
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8SRI
 | | Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, closed state | | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ... | | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | | Deposit date: | 2023-05-05 | | Release date: | 2024-05-15 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.73 Å) | | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
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8SRB
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of EDTA and ADP-ribose | | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, TRPM2 chanzyme | | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | | Deposit date: | 2023-05-05 | | Release date: | 2024-05-08 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.82 Å) | | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
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8SRH
 | | Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, open state | | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ... | | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | | Deposit date: | 2023-05-05 | | Release date: | 2024-05-15 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.79 Å) | | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
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