5WPT
 
 | | Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed II conformation at 3.75 Angstrom resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION | | Authors: | Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y. | | Deposit date: | 2017-08-07 | | Release date: | 2017-10-18 | | Last modified: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (3.75 Å) | | Cite: | Structure of mammalian endolysosomal TRPML1 channel in nanodiscs.
Nature, 550, 2017
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5WPV
 | | Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs at 3.59 Angstrom resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION | | Authors: | Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y. | | Deposit date: | 2017-08-07 | | Release date: | 2017-10-18 | | Last modified: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | Structure of mammalian endolysosomal TRPML1 channel in nanodiscs.
Nature, 550, 2017
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5WPQ
 | | Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed I conformation at 3.64 Angstrom resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION | | Authors: | Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y. | | Deposit date: | 2017-08-07 | | Release date: | 2017-10-18 | | Last modified: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (3.64 Å) | | Cite: | Structure of mammalian endolysosomal TRPML1 channel in nanodiscs.
Nature, 550, 2017
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8HVT
 | | Structure of the human CLC-7/Ostm1 complex reveals a novel state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H(+)/Cl(-) exchange transporter 7, Osteopetrosis-associated transmembrane protein 1, ... | | Authors: | Zhang, Z.X, Chen, L, He, J, She, J. | | Deposit date: | 2022-12-27 | | Release date: | 2024-01-03 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure of the human CLC-7/Ostm1 complex reveals a novel state
JUSTC, 53, 2023
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6BCL
 | | cryo-EM structure of TRPM4 in apo state with long coiled coil at 3.5 angstrom resolution | | Descriptor: | SODIUM ION, Transient receptor potential cation channel subfamily M member 4 | | Authors: | Guo, J, She, J, Chen, Q, Bai, X, Jiang, Y. | | Deposit date: | 2017-10-20 | | Release date: | 2017-12-13 | | Last modified: | 2019-11-20 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Structures of the calcium-activated, non-selective cation channel TRPM4.
Nature, 552, 2017
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6BCJ
 | | cryo-EM structure of TRPM4 in apo state with short coiled coil at 3.1 angstrom resolution | | Descriptor: | SODIUM ION, Transient receptor potential cation channel subfamily M member 4 | | Authors: | Guo, J, She, J, Chen, Q, Bai, X, Jiang, Y. | | Deposit date: | 2017-10-20 | | Release date: | 2017-12-13 | | Last modified: | 2019-11-20 | | Method: | ELECTRON MICROSCOPY (3.14 Å) | | Cite: | Structures of the calcium-activated, non-selective cation channel TRPM4.
Nature, 552, 2017
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6BCQ
 | | cryo-EM structure of TRPM4 in ATP bound state with long coiled coil at 3.3 angstrom resolution | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Transient receptor potential cation channel subfamily M member 4 | | Authors: | Guo, J, She, J, Chen, Q, Bai, X, Jiang, Y. | | Deposit date: | 2017-10-20 | | Release date: | 2017-12-13 | | Last modified: | 2019-11-20 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structures of the calcium-activated, non-selective cation channel TRPM4.
Nature, 552, 2017
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6BCO
 | | cryo-EM structure of TRPM4 in ATP bound state with short coiled coil at 2.9 angstrom resolution | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Transient receptor potential cation channel subfamily M member 4 | | Authors: | Guo, J, She, J, Chen, Q, Bai, X, Jiang, Y. | | Deposit date: | 2017-10-20 | | Release date: | 2017-12-13 | | Last modified: | 2019-11-20 | | Method: | ELECTRON MICROSCOPY (2.88 Å) | | Cite: | Structures of the calcium-activated, non-selective cation channel TRPM4.
Nature, 552, 2017
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5X3V
 | | Structure of human SHMT2 protein mutant | | Descriptor: | SULFATE ION, Serine hydroxymethyltransferase, mitochondrial | | Authors: | Li, J, Sheng, J. | | Deposit date: | 2017-02-09 | | Release date: | 2018-02-14 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structure of human SHMT2 protein mutant
To Be Published
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7S4A
 | | MRG15 complex with PALB2 peptide | | Descriptor: | Mortality factor 4-like protein 1, Partner and localizer of BRCA2 | | Authors: | Korolev, S, Deveryshetty, J. | | Deposit date: | 2021-09-08 | | Release date: | 2022-05-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.693 Å) | | Cite: | Structural Insight into the Mechanism of PALB2 Interaction with MRG15.
Genes (Basel), 12, 2021
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7D32
 | | The TBA-Pb2+ complex in P41212 space group | | Descriptor: | DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3'), LEAD (II) ION | | Authors: | Liu, H.H, Gao, Y.Q, Sheng, J, Gan, J.H. | | Deposit date: | 2020-09-18 | | Release date: | 2021-09-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.707 Å) | | Cite: | Structure-guided development of Pb 2+ -binding DNA aptamers.
Sci Rep, 12, 2022
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7D31
 | | The TBA-Pb2+ complex in P41212 space group | | Descriptor: | DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3'), LEAD (II) ION | | Authors: | Liu, H.H, Gao, Y.Q, Sheng, J, Gan, J.H. | | Deposit date: | 2020-09-18 | | Release date: | 2021-09-22 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.396 Å) | | Cite: | Structure-guided development of Pb 2+ -binding DNA aptamers.
Sci Rep, 12, 2022
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7D33
 | | The Pb2+ complexed structure of TBA G8C mutant | | Descriptor: | DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*CP*TP*GP*GP*TP*TP*GP*G)-3'), LEAD (II) ION | | Authors: | Liu, H.H, Gao, Y.Q, Sheng, J, Gan, J.H. | | Deposit date: | 2020-09-18 | | Release date: | 2021-09-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.117 Å) | | Cite: | Structure-guided development of Pb 2+ -binding DNA aptamers.
Sci Rep, 12, 2022
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2LGK
 | | NMR Structure of UHRF1 PHD domains in a complex with histone H3 peptide | | Descriptor: | E3 ubiquitin-protein ligase UHRF1, ZINC ION, histone H3 peptide | | Authors: | Wang, C, Shen, J, Yang, Z, Chen, P, Zhao, B, Hu, W, Lan, W, Tong, X, Wu, H, Li, G, Cao, C. | | Deposit date: | 2011-07-28 | | Release date: | 2011-09-28 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger.
Cell Res., 21, 2011
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4X80
 | | Crystal Structure of murine 7B4 Fab monoclonal antibody against ADAMTS5 | | Descriptor: | IgG1 7B4 FAB Heavy chain, IgG1 7B4 FAB Light Chain | | Authors: | Larkin, J, Lohr, T.A, Elefante, L, Shearin, J, Matico, R, Su, J.-L, Xue, Y, Liu, F, Genell, C, Miller, R.E, Tran, P.B, Malfait, A.-M, Maier, C.C, Matheny, C.J. | | Deposit date: | 2014-12-09 | | Release date: | 2015-04-08 | | Last modified: | 2015-08-05 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification.
Osteoarthr. Cartil., 23, 2015
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4X8J
 | | Crystal Structure of murine 12F4 Fab monoclonal antibody against ADAMTS5 | | Descriptor: | 12F4 FAB Heavy chain, 12F4 FAB Light chain, NONAETHYLENE GLYCOL, ... | | Authors: | Larkin, J, Lohr, T.A, Elefante, L, Shearin, J, Matico, R, Su, J.-L, Xue, Y, Liu, F, Genell, C, Miller, R.E, Tran, P.B, Malfait, A.-M, Maier, C.C, Matheny, C.J. | | Deposit date: | 2014-12-10 | | Release date: | 2015-04-08 | | Last modified: | 2015-08-05 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification.
Osteoarthr. Cartil., 23, 2015
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5H4B
 | | Crystal structure of Cbln4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-4 | | Authors: | Zhong, C, Shen, J, Zhang, H, Ding, J. | | Deposit date: | 2016-10-31 | | Release date: | 2017-09-13 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions.
Cell Rep, 20, 2017
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4WM7
 | | Crystal Structure of Human Enterovirus D68 in Complex with Pleconaril | | Descriptor: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, VP1, VP2, ... | | Authors: | Liu, Y, Sheng, J, Fokine, A, Meng, G, Long, F, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2014-10-08 | | Release date: | 2015-01-14 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Science, 347, 2015
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4WM8
 | | Crystal Structure of Human Enterovirus D68 | | Descriptor: | DECANOIC ACID, VP1, VP2, ... | | Authors: | Liu, Y, Sheng, J, Fokine, A, Meng, G, Long, F, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2014-10-08 | | Release date: | 2015-01-14 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Science, 347, 2015
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7OUO
 | | Crystal structure of RNA duplex [UCGUGCGA]2 in complex with Ba2+ cation | | Descriptor: | BARIUM ION, RNA (5'-R(*UP*CP*GP*UP*GP*CP*GP*A)-3') | | Authors: | Ruszkowski, M, Mao, S, Zheng, Y.Y, Ruszkowska, A, Sheng, J. | | Deposit date: | 2021-06-12 | | Release date: | 2022-03-30 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.212 Å) | | Cite: | Structural Insights Into the 5'UG/3'GU Wobble Tandem in Complex With Ba 2+ Cation.
Front Mol Biosci, 8, 2021
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5H48
 | | Crystal structure of Cbln1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-1 | | Authors: | Zhong, C, Shen, J, Zhang, H, Ding, J. | | Deposit date: | 2016-10-31 | | Release date: | 2017-09-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions.
Cell Rep, 20, 2017
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5H4C
 | | Crystal structure of Cbln4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein Cbln4 | | Authors: | Zhong, C, Shen, J, Zhang, H, Ding, J. | | Deposit date: | 2016-10-31 | | Release date: | 2017-09-06 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions.
Cell Rep, 20, 2017
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5H49
 | | Crystal structure of Cbln1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-1 | | Authors: | Zhong, C, Shen, J, Zhang, H, Ding, J. | | Deposit date: | 2016-10-31 | | Release date: | 2017-09-13 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions.
Cell Rep, 20, 2017
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8EF6
 | | Morphine-bound mu-opioid receptor-Gi complex | | Descriptor: | (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | | Deposit date: | 2022-09-08 | | Release date: | 2022-11-09 | | Last modified: | 2022-11-30 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
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8EF5
 | | Fentanyl-bound mu-opioid receptor-Gi complex | | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | | Deposit date: | 2022-09-08 | | Release date: | 2022-11-09 | | Last modified: | 2022-11-30 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
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