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1A23
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BU of 1a23 by Molmil
SOLUTION NMR STRUCTURE OF REDUCED DSBA FROM ESCHERICHIA COLI, MINIMIZED AVERAGE STRUCTURE
Descriptor: DSBA
Authors:Schirra, H.J, Renner, C, Czisch, M, Huber-Wunderlich, M, Holak, T.A, Glockshuber, R.
Deposit date:1998-01-15
Release date:1998-09-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of reduced DsbA from Escherichia coli in solution.
Biochemistry, 37, 1998
1A24
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BU of 1a24 by Molmil
SOLUTION NMR STRUCTURE OF REDUCED DSBA FROM ESCHERICHIA COLI, FAMILY OF 20 STRUCTURES
Descriptor: DSBA
Authors:Schirra, H.J, Renner, C, Czisch, M, Huber-Wunderlich, M, Holak, T.A, Glockshuber, R.
Deposit date:1998-01-15
Release date:1998-09-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of reduced DsbA from Escherichia coli in solution.
Biochemistry, 37, 1998
6T41
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BU of 6t41 by Molmil
CDK8/Cyclin C in complex with N-(4-chlorobenzyl)isoquinolin-4-amine
Descriptor: 1,2-ETHANEDIOL, Cyclin-C, Cyclin-dependent kinase 8, ...
Authors:Schneider, E.V, Maskos, K, Huber, R, Kuhn, C.-D.
Deposit date:2019-10-11
Release date:2020-01-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A precisely positioned MED12 activation helix stimulates CDK8 kinase activity.
Proc.Natl.Acad.Sci.USA, 117, 2020
1TYX
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BU of 1tyx by Molmil
TITLE OF TAILSPIKE-PROTEIN
Descriptor: TAILSPIKE PROTEIN, alpha-D-galactopyranose-(1-2)-[alpha-D-Abequopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-alpha-L-rhamnopyranose-(1-3)-alpha-D-galactopyranose-(1-2)-[alpha-D-Abequopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-alpha-L-rhamnopyranose
Authors:Steinbacher, S, Huber, R.
Deposit date:1996-07-26
Release date:1997-07-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of phage P22 tailspike protein complexed with Salmonella sp. O-antigen receptors.
Proc.Natl.Acad.Sci.USA, 93, 1996
1TYU
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BU of 1tyu by Molmil
STRUCTURE OF TAILSPIKE-PROTEIN
Descriptor: TAILSPIKE PROTEIN, alpha-D-galactopyranose-(1-2)-[alpha-D-Tyvelopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-alpha-L-rhamnopyranose-(1-3)-alpha-D-galactopyranose-(1-2)-[alpha-D-Tyvelopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-alpha-L-rhamnopyranose
Authors:Steinbacher, S, Huber, R.
Deposit date:1996-07-26
Release date:1997-07-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of phage P22 tailspike protein complexed with Salmonella sp. O-antigen receptors.
Proc.Natl.Acad.Sci.USA, 93, 1996
5JDW
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BU of 5jdw by Molmil
CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH GLYCINE
Descriptor: GLYCINE, PROTEIN (L-ARGININE:GLYCINE AMIDINOTRANSFERASE)
Authors:Fritsche, E, Humm, A, Huber, R.
Deposit date:1998-10-07
Release date:1999-02-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The ligand-induced structural changes of human L-Arginine:Glycine amidinotransferase. A mutational and crystallographic study.
J.Biol.Chem., 274, 1999
2IXS
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BU of 2ixs by Molmil
Structure of SdaI restriction endonuclease
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SDAI RESTRICTION ENDONUCLEASE, ...
Authors:Tamulaitiene, G, Jakubauskas, A, Urbanke, C, Huber, R, Grazulis, S, Siksnys, V.
Deposit date:2006-07-11
Release date:2006-09-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of the Rare-Cutting Restriction Enzyme Sdai Reveals Unexpected Domain Architecture
Structure, 14, 2006
4CTS
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BU of 4cts by Molmil
CRYSTAL STRUCTURE ANALYSIS AND MOLECULAR MODEL OF A COMPLEX OF CITRATE SYNTHASE WITH OXALOACETATE AND S-ACETONYL-COENZYME A
Descriptor: CITRATE SYNTHASE, OXALOACETATE ION
Authors:Remington, S, Wiegand, G, Huber, R.
Deposit date:1984-01-27
Release date:1984-07-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure analysis and molecular model of a complex of citrate synthase with oxaloacetate and S-acetonyl-coenzyme A
J.Mol.Biol., 174, 1984
7A3F
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BU of 7a3f by Molmil
Crystal structure of apo DPP9
Descriptor: Dipeptidyl peptidase 9, GLYCEROL, PHOSPHATE ION
Authors:Ross, B.H, Huber, R.
Deposit date:2020-08-18
Release date:2021-06-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Discovery and Development of 4-Oxo-beta-Lactams as Novel Inhibitors of Dipeptidyl Peptidases 8 and 9
To Be Published
7A3J
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BU of 7a3j by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, A272
Descriptor: 2-ethyl-2-methanoyl-~{N}-[3-[[4-(naphthalen-1-ylmethyl)piperazin-1-yl]methyl]phenyl]butanamide, CHLORIDE ION, Dipeptidyl peptidase 8, ...
Authors:Ross, B.H, Huber, R.
Deposit date:2020-08-18
Release date:2021-06-30
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 2022
7A3G
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BU of 7a3g by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, 91
Descriptor: 1-[3-(7,8-dihydro-5~{H}-[1,3]dioxolo[4,5-g]isoquinolin-6-ylmethyl)phenyl]-3,3-diethyl-azetidine-2,4-dione, CHLORIDE ION, Dipeptidyl peptidase 8, ...
Authors:Ross, B.H, Huber, R.
Deposit date:2020-08-18
Release date:2021-06-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 2022
7A3I
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BU of 7a3i by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, LMC375
Descriptor: CHLORIDE ION, Dipeptidyl peptidase 8, SODIUM ION, ...
Authors:Ross, B.H, Huber, R.
Deposit date:2020-08-18
Release date:2021-06-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery and Development of 4-Oxo-beta-Lactams as Novel Inhibitors of Dipeptidyl Peptidases 8 and 9
To Be Published
7A3L
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BU of 7a3l by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, A241
Descriptor: 2-ethyl-2-methanoyl-~{N}-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]butanamide, CHLORIDE ION, Dipeptidyl peptidase 8, ...
Authors:Ross, B.H, Huber, R.
Deposit date:2020-08-18
Release date:2021-06-30
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 2022
7A3K
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BU of 7a3k by Molmil
Crystal structure of DPP8 in complex with a b-lactam based inhibitor, A296.1
Descriptor: 1-[3-[[4-[(4-bromophenyl)methyl]piperazin-1-yl]methyl]phenyl]azetidin-2-one, CHLORIDE ION, Dipeptidyl peptidase 8, ...
Authors:Ross, B.H, Huber, R.
Deposit date:2020-08-18
Release date:2021-07-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Discovery and Development of 4-Oxo-beta-Lactams as Novel Inhibitors of Dipeptidyl Peptidases 8 and 9
To Be Published
7AYR
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BU of 7ayr by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, B115
Descriptor: Dipeptidyl peptidase 8, PHOSPHATE ION, trimethylamine oxide, ...
Authors:Ross, B.H, Huber, R.
Deposit date:2020-11-13
Release date:2021-06-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 2022
9JDW
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BU of 9jdw by Molmil
CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH ALPHA-AMINO BUTYRIC ACID
Descriptor: ALPHA-AMINOBUTYRIC ACID, PROTEIN (L-ARGININE:GLYCINE AMIDINOTRANSFERASE)
Authors:Fritsche, E, Humm, A, Huber, R.
Deposit date:1998-10-12
Release date:1999-02-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The ligand-induced structural changes of human L-Arginine:Glycine amidinotransferase. A mutational and crystallographic study.
J.Biol.Chem., 274, 1999
7AYQ
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BU of 7ayq by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, B114
Descriptor: Dipeptidyl peptidase 8, GLYCEROL, PHOSPHATE ION, ...
Authors:Ross, B, Huber, R.
Deposit date:2020-11-13
Release date:2021-06-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 2022
2JDW
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BU of 2jdw by Molmil
CRYSTAL STRUCTURE AND MECHANISM OF L-ARGININE: GLYCINE AMIDINOTRANSFERASE: A MITOCHONDRIAL ENZYME INVOLVED IN CREATINE BIOSYNTHESIS
Descriptor: L-ARGININE:GLYCINE AMIDINOTRANSFERASE
Authors:Humm, A, Fritsche, E, Steinbacher, S, Huber, R.
Deposit date:1997-01-24
Release date:1998-01-28
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis.
EMBO J., 16, 1997
1TOC
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BU of 1toc by Molmil
STRUCTURE OF SERINE PROTEINASE
Descriptor: ORNITHODORIN, THROMBIN
Authors:Van De Locht, A, Huber, R, Bode, W.
Deposit date:1996-07-20
Release date:1997-07-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The ornithodorin-thrombin crystal structure, a key to the TAP enigma?
EMBO J., 15, 1996
2IMM
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BU of 2imm by Molmil
Refined crystal structure of a recombinant immunoglobulin domain and a complementarity-determining region 1-grafted mutant
Descriptor: ACETATE ION, IGA-KAPPA MCPC603 FV (LIGHT CHAIN), SULFATE ION
Authors:Steipe, B, Huber, R.
Deposit date:1993-03-01
Release date:1993-07-15
Last modified:2024-12-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Refined crystal structure of a recombinant immunoglobulin domain and a complementarity-determining region 1-grafted mutant.
J.Mol.Biol., 225, 1992
4AZU
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BU of 4azu by Molmil
CRYSTAL STRUCTURE ANALYSIS OF OXIDIZED PSEUDOMONAS AERUGINOSA AZURIN AT PH 5.5 AND PH 9.0. A PH-INDUCED CONFORMATIONAL TRANSITION INVOLVES A PEPTIDE BOND FLIP
Descriptor: AZURIN, COPPER (II) ION, NITRATE ION
Authors:Nar, H, Messerschmidt, A, Huber, R.
Deposit date:1993-06-23
Release date:1994-01-31
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure analysis of oxidized Pseudomonas aeruginosa azurin at pH 5.5 and pH 9.0. A pH-induced conformational transition involves a peptide bond flip.
J.Mol.Biol., 221, 1991
1U9L
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BU of 1u9l by Molmil
Structural basis for a NusA- protein N interaction
Descriptor: GOLD ION, Lambda N, Transcription elongation protein nusA
Authors:Bonin, I, Muehlberger, R, Bourenkov, G.P, Huber, R, Bacher, A, Richter, G, Wahl, M.C.
Deposit date:2004-08-10
Release date:2004-08-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the interaction of Escherichia coli NusA with protein N of phage lambda
Proc.Natl.Acad.Sci.Usa, 101, 2004
2MVX
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BU of 2mvx by Molmil
Atomic-resolution 3D structure of amyloid-beta fibrils: the Osaka mutation
Descriptor: Amyloid beta A4 protein
Authors:Schuetz, A.K, Vagt, T, Huber, M, Ovchinnikova, O.Y, Cadalbert, R, Wall, J, Guentert, P, Bockmann, A, Glockshuber, R, Meier, B.H.
Deposit date:2014-10-17
Release date:2014-11-26
Last modified:2024-05-01
Method:SOLID-STATE NMR
Cite:Atomic-Resolution Three-Dimensional Structure of Amyloid beta Fibrils Bearing the Osaka Mutation.
Angew.Chem.Int.Ed.Engl., 54, 2015
6Z6F
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BU of 6z6f by Molmil
HDAC-PC
Descriptor: HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ...
Authors:Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R.
Deposit date:2020-05-28
Release date:2021-02-17
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
6Z6H
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BU of 6z6h by Molmil
HDAC-DC
Descriptor: HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ...
Authors:Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R.
Deposit date:2020-05-28
Release date:2021-02-17
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (8.55 Å)
Cite:Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021

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