6Y5W
| Crystal structure of the envelope glycoprotein complex of Andes virus in a near postfusion conformation | Descriptor: | Envelope polyprotein,Envelope polyprotein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Serris, A, Rey, F.A, Guardado-Calvo, P. | Deposit date: | 2020-02-26 | Release date: | 2020-10-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism. Cell, 183, 2020
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6ZJM
| Atomic model of Andes virus glycoprotein spike tetramer generated by fitting into a Tula virus reconstruction | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein, ... | Authors: | Stass, R, Huiskonen, J.T, Rey, F, Guardado-Calvo, P. | Deposit date: | 2020-06-29 | Release date: | 2020-10-14 | Last modified: | 2020-10-28 | Method: | ELECTRON MICROSCOPY (11.4 Å) | Cite: | The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism. Cell, 183, 2020
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8LDH
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3LPL
| E. coli pyruvate dehydrogenase complex E1 component E571A mutant | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Furey, W. | Deposit date: | 2010-02-05 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Communication between thiamin cofactors in the Escherichia coli pyruvate dehydrogenase complex E1 component active centers: evidence for a "direct pathway" between the 4'-aminopyrimidine N1' atoms. J.Biol.Chem., 285, 2010
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3LQ2
| E. coli pyruvate dehydrogenase complex E1 E235A mutant with low TDP concentration | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Furey, W. | Deposit date: | 2010-02-08 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Communication between thiamin cofactors in the Escherichia coli pyruvate dehydrogenase complex E1 component active centers: evidence for a "direct pathway" between the 4'-aminopyrimidine N1' atoms. J.Biol.Chem., 285, 2010
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3LDH
| A comparison of the structures of apo dogfish m4 lactate dehydrogenase and its ternary complexes | Descriptor: | LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID | Authors: | White, J.L, Hackert, M.L, Buehner, M, Adams, M.J, Ford, G.C, Lentzjunior, P.J, Smiley, I.E, Steindel, S.J, Rossmann, M.G. | Deposit date: | 1974-06-06 | Release date: | 1977-04-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A comparison of the structures of apo dogfish M4 lactate dehydrogenase and its ternary complexes. J.Mol.Biol., 102, 1976
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3LQ4
| E. coli pyruvate dehydrogenase complex E1 E235A mutant with high TDP concentration | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Furey, W. | Deposit date: | 2010-02-08 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Communication between thiamin cofactors in the Escherichia coli pyruvate dehydrogenase complex E1 component active centers: evidence for a "direct pathway" between the 4'-aminopyrimidine N1' atoms. J.Biol.Chem., 285, 2010
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6LDH
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6MAM
| Cleaved Ebola GP in complex with a broadly neutralizing human antibody, ADI-15946 | Descriptor: | ADI-15946 Fab Heavy Chain, ADI-15946 Fab Light Chain, Envelope glycoprotein, ... | Authors: | West, B.R, Moyer, C.L, Fusco, M.L, Saphire, E.O. | Deposit date: | 2018-08-28 | Release date: | 2019-03-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Structural basis of broad ebolavirus neutralization by a human survivor antibody. Nat. Struct. Mol. Biol., 26, 2019
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7SGT
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7A5A
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7A59
| Crimean-Congo Hemorrhagic Fever Virus Envelope Glycoprotein Gc W1191H/W1197A/W1199A Mutant in Postfusion Conformation (Orthorhombic Crystal Form) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Envelopment polyprotein, ... | Authors: | Hellert, J, Guardado-Calvo, P, Rey, F.A. | Deposit date: | 2020-08-20 | Release date: | 2021-10-06 | Last modified: | 2022-04-20 | Method: | X-RAY DIFFRACTION (2.197 Å) | Cite: | Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies. Science, 375, 2022
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6VKF
| CCHFV GP38 (IbAr10200) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GP38 | Authors: | Mishra, A.K, McLellan, J.S. | Deposit date: | 2020-01-20 | Release date: | 2020-02-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.524 Å) | Cite: | Structure and Characterization of Crimean-Congo Hemorrhagic Fever Virus GP38. J.Virol., 94, 2020
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5JO4
| Antibody Fab Fragment Complex | Descriptor: | D80 Fab Heavy Chain, D80 Fab Light Chain, G6 Fab Heavy Chain, ... | Authors: | Zhang, Z, Prachanronarong, K.P, Marasco, W.A, Schiffer, C.A.S. | Deposit date: | 2016-05-01 | Release date: | 2017-11-08 | Last modified: | 2019-11-27 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Structural Basis of an Influenza Hemagglutinin Stem-Directed Antibody Retaining the G6 Idiotype To Be Published
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1XOB
| THIOREDOXIN (REDUCED DITHIO FORM), NMR, 20 STRUCTURES | Descriptor: | THIOREDOXIN | Authors: | Jeng, M.-F, Campbell, A.P, Begley, T, Holmgren, A, Case, D.A, Wright, P.E, Dyson, H.J. | Deposit date: | 1995-11-28 | Release date: | 1996-06-10 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin. Structure, 2, 1994
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1XOA
| THIOREDOXIN (OXIDIZED DISULFIDE FORM), NMR, 20 STRUCTURES | Descriptor: | THIOREDOXIN | Authors: | Jeng, M.-F, Campbell, A.P, Begley, T, Holmgren, A, Case, D.A, Wright, P.E, Dyson, H.J. | Deposit date: | 1995-11-28 | Release date: | 1996-06-10 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin. Structure, 2, 1994
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4RCD
| Crystal structure of BACE1 in complex with a 2-aminooxazoline 4-azaxanthene inhibitor | Descriptor: | (5S)-7-(2-fluoropyridin-3-yl)-3-[(3-methyloxetan-3-yl)ethynyl]spiro[chromeno[2,3-b]pyridine-5,4'-[1,3]oxazol]-2'-amine, Beta-secretase 1, GLYCEROL, ... | Authors: | Whittington, D.A, Long, A.M. | Deposit date: | 2014-09-15 | Release date: | 2015-01-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Inhibitors of beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1): Identification of (S)-7-(2-Fluoropyridin-3-yl)-3-((3-methyloxetan-3-yl)ethynyl)-5'H-spiro[chromeno[2,3-b]pyridine-5,4'-oxazol]-2'-amine (AMG-8718). J.Med.Chem., 57, 2014
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7L7R
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7KX4
| Anti-CCHFV ADI-36121 Fab | Descriptor: | ADI-36121 Fab heavy chain, ADI-36121 Fab light chain | Authors: | Mishra, A.K, McLellan, J.S. | Deposit date: | 2020-12-03 | Release date: | 2021-12-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies. Science, 375, 2022
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6A4T
| Crystal structure of Peptidase E from Deinococcus radiodurans R1 | Descriptor: | Peptidase E | Authors: | Yadav, P, Goyal, V.G, Kumar, A, Gokhale, S.M, Makde, R.D. | Deposit date: | 2018-06-20 | Release date: | 2019-06-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Catalytic triad heterogeneity in S51 peptidase family: Structural basis for functional variability. Proteins, 87, 2019
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3S88
| Crystal structure of Sudan Ebolavirus Glycoprotein (strain Gulu) bound to 16F6 | Descriptor: | 16F6 - Heavy chain, 16F6 - Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Saphire, E.O, Dias, J.M, Bale, S. | Deposit date: | 2011-05-27 | Release date: | 2011-12-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.351 Å) | Cite: | A shared structural solution for neutralizing ebolaviruses. Nat.Struct.Mol.Biol., 18, 2011
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1LDM
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8U1G
| Prefusion-stabilized SARS-CoV-2 S2 subunit | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2 | Authors: | Hsieh, C.-L, McLellan, J.S. | Deposit date: | 2023-08-31 | Release date: | 2024-01-24 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Prefusion-stabilized SARS-CoV-2 S2-only antigen provides protection against SARS-CoV-2 challenge. Nat Commun, 15, 2024
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8VAO
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8VWW
| CCHFV GP38 bound to ADI-46152 and ADI-58048 Fabs | Descriptor: | ADI-46152 Fab Heavy Chain, ADI-46152 Fab Light Chain, ADI-58048 Fab Heavy Chain, ... | Authors: | Hjorth, C.K, McLellan, J.S. | Deposit date: | 2024-02-02 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38. Cell Rep, 43, 2024
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