3LQ2

E. coli pyruvate dehydrogenase complex E1 E235A mutant with low TDP concentration

Summary for 3LQ2

• Entry DOI: 10.2210/pdb3lq2/pdb
• Related: 2IEA 3LPL 3LQ4
• Descriptor: Pyruvate dehydrogenase E1 component, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: thdp, pyruvate dehydrogenase, glycolysis, metal-binding, oxidoreductase, pyruvate, thiamine pyrophosphate
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 200525.75

Authors

Furey, W. (deposition date: 2010-02-08, release date: 2010-03-02, Last modification date: 2023-09-06)

• Primary citation: Nemeria, N.S.,Arjunan, P.,Chandrasekhar, K.,Mossad, M.,Tittmann, K.,Furey, W.,Jordan, F.; Communication between thiamin cofactors in the Escherichia coli pyruvate dehydrogenase complex E1 component active centers: evidence for a "direct pathway" between the 4'-aminopyrimidine N1' atoms.; J.Biol.Chem., 285:11197-11209, 2010; PubMed: 20106967; DOI: 10.1074/jbc.M109.069179

Experimental method

X-RAY DIFFRACTION (1.96 Å)