Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004739 | molecular_function | pyruvate dehydrogenase (acetyl-transferring) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004739 | molecular_function | pyruvate dehydrogenase (acetyl-transferring) activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE TPP A 887 |
| Chain | Residue |
| A | SER109 |
| A | ASN260 |
| A | GLN262 |
| A | ARG263 |
| A | LEU264 |
| A | MG888 |
| A | HOH1010 |
| A | HOH1092 |
| A | HOH1117 |
| B | ASP521 |
| B | GLU522 |
| A | GLN140 |
| B | ILE569 |
| B | GLU571 |
| B | PHE602 |
| B | ARG606 |
| B | HIS640 |
| B | HOH1201 |
| A | HIS142 |
| A | VAL192 |
| A | MET194 |
| A | GLY229 |
| A | ASP230 |
| A | GLY231 |
| A | GLU232 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 888 |
| Chain | Residue |
| A | ASP230 |
| A | ASN260 |
| A | GLN262 |
| A | ARG263 |
| A | TPP887 |
| A | HOH1092 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 889 |
| Chain | Residue |
| A | ARG79 |
| A | ARG82 |
| A | ARG86 |
| A | TYR394 |
| A | HOH1032 |
| A | HOH1036 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EPE A 890 |
| Chain | Residue |
| A | VAL65 |
| A | GLU66 |
| A | GLU67 |
| A | GLN68 |
| A | PRO69 |
| A | GLU70 |
| A | LYS367 |
| A | HOH1008 |
| B | TYR787 |
| B | GLN790 |
| site_id | AC5 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE TPP B 887 |
| Chain | Residue |
| A | ASP521 |
| A | ILE569 |
| A | GLU571 |
| A | PHE602 |
| A | HIS640 |
| A | HOH1156 |
| B | SER109 |
| B | GLN140 |
| B | HIS142 |
| B | VAL192 |
| B | MET194 |
| B | GLY229 |
| B | ASP230 |
| B | GLY231 |
| B | GLU232 |
| B | ASN258 |
| B | ASN260 |
| B | GLN262 |
| B | LYS392 |
| B | MG888 |
| B | HOH982 |
| B | HOH1092 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 888 |
| Chain | Residue |
| B | ASP230 |
| B | ASN260 |
| B | GLN262 |
| B | TPP887 |
| B | HOH1092 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 B 889 |
| Chain | Residue |
| B | ARG79 |
| B | ARG82 |
| B | ARG86 |
| B | TYR394 |
| B | PHE424 |
| B | HOH999 |
| B | HOH1084 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"evidenceCode":"ECO:0000250"}]} |
