7SGT

Domain III (EDIII) of the POWV E glycoprotein

Summary for 7SGT

• Entry DOI: 10.2210/pdb7sgt/pdb
• Related: 7KYL
• NMR Information: BMRB: 30959
• Descriptor: Envelope protein E (1 entity in total)
• Functional Keywords: powassan virus, nanoparticle immunogen, flavivirus, monoclonal antibody, viral protein
• Biological source: Tick-borne powassan virus (strain lb)
• Total number of polymer chains: 1
• Total formula weight: 11182.76

Authors

Harris, R.,Cahill, S.M.,Cowburn, D. (deposition date: 2021-10-07, release date: 2022-05-18, Last modification date: 2022-06-22)

• Primary citation: Malonis, R.J.,Georgiev, G.I.,Haslwanter, D.,VanBlargan, L.A.,Fallon, G.,Vergnolle, O.,Cahill, S.M.,Harris, R.,Cowburn, D.,Chandran, K.,Diamond, M.S.,Lai, J.R.; A Powassan virus domain III nanoparticle immunogen elicits neutralizing and protective antibodies in mice.; Plos Pathog., 18:e1010573-e1010573, 2022; PubMed: 35679349; DOI: 10.1371/journal.ppat.1010573

Experimental method

SOLUTION NMR