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4OJF
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BU of 4ojf by Molmil
Humanised 3D6 Fab complexed to amyloid beta 1-8
Descriptor: Amyloid beta A4 protein, Humanised 3D6 Fab Heavy Chain, Humanised 3D6 Fab Light Chain
Authors:Miles, L.A, Crespi, G.A.N, Parker, M.W.
Deposit date:2014-01-21
Release date:2015-01-28
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-beta
ACTA CRYSTALLOGR.,SECT.F, 70, 2014
5OHT
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BU of 5oht by Molmil
A GH31 family sulfoquinovosidase from E. coli in complex with aza-sugar inhibitor IFGSQ
Descriptor: CALCIUM ION, Sulfoquinovosidase, [(3~{S},4~{R},5~{R})-4,5-bis(oxidanyl)piperidin-3-yl]methanesulfonic acid
Authors:Jin, Y, Williams, S.J, Goddard-Borger, E, Davies, G.J.
Deposit date:2017-07-18
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases.
ACS Cent Sci, 4, 2018
5OHS
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BU of 5ohs by Molmil
A GH31 family sulfoquinovosidase mutant D455N in complex with pNPSQ
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 4-nitrophenyl alpha-D-6-sulfoquinovoside, ...
Authors:Jin, Y, Williams, S.J, Goddard-Borger, E, Davies, G.J.
Deposit date:2017-07-18
Release date:2018-08-08
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases.
ACS Cent Sci, 4, 2018
5OHY
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BU of 5ohy by Molmil
A GH31 family sulfoquinovosidase in complex with aza-sugar inhibitor IFGSQ
Descriptor: 1,2-ETHANEDIOL, Alpha-glucosidase yihQ, PHOSPHATE ION, ...
Authors:Jin, Y, Williams, S.J, Goddard-Borger, E, Davies, G.J.
Deposit date:2017-07-18
Release date:2018-08-08
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases.
ACS Cent Sci, 4, 2018
5OPM
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BU of 5opm by Molmil
Crystal structure of D52N/R238W cN-II mutant bound to dATP and free phosphate
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Cytosolic purine 5'-nucleotidase, GLYCEROL, ...
Authors:Hnizda, A, Pachl, P, Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPL
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BU of 5opl by Molmil
Crystal structure of K25E cN-II mutant
Descriptor: Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION
Authors:Kugler, M, Hnizda, A, Pachl, P, Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPK
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BU of 5opk by Molmil
Crystal structure of D52N/R367Q cN-II mutant bound to dATP and free phosphate
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Cytosolic purine 5'-nucleotidase, GLYCEROL, ...
Authors:Hnizda, A, Pachl, P, Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPP
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BU of 5opp by Molmil
Crystal structure of S408R cN-II mutant
Descriptor: BROMIDE ION, Cytosolic purine 5'-nucleotidase, GLYCEROL, ...
Authors:Hnizda, A, Pachl, P, Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPN
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BU of 5opn by Molmil
Crystal structure of R39Q cN-II mutant
Descriptor: Cytosolic purine 5'-nucleotidase, GLYCEROL
Authors:Hnizda, A, Pachl, P, Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5DJL
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BU of 5djl by Molmil
Structure of WT Human Glutathione Transferase in complex with cisplatin in the presence of glutathione.
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CARBONATE ION, ...
Authors:Parker, L.J.
Deposit date:2015-09-02
Release date:2016-11-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A structure-based mechanism of cisplatin resistance mediated by Glutathione Transferase P1-1
Proc.Natl.Acad.Sci.USA, 2019
5DAL
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BU of 5dal by Molmil
Crystal Structure of human Glutathione Transferase Pi complexed with a metalloid in the presence of Glutathione
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Di-glutathione-PhenylArsine, GLUTATHIONE, ...
Authors:Parker, L.J, Parker, M.W, Morton, C.J.
Deposit date:2015-08-20
Release date:2016-12-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics
To Be Published
5DDL
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BU of 5ddl by Molmil
Crystal Structure of WT Human Glutathione Transferase Pi soaked with a metalloid then back-soaked with glutathione
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Di-glutathione-PhenylArsine, ...
Authors:Parker, L.J, Parker, M.W, Morton, C.J.
Deposit date:2015-08-25
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics
To Be Published
5DAK
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BU of 5dak by Molmil
Crystal Structure of human Glutathione Transferase Pi complexed with a metalloid in the absence of Glutathione
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ARSENIC, Glutathione S-transferase P
Authors:Parker, L.J, Parker, M.W, Morton, C.J.
Deposit date:2015-08-20
Release date:2016-12-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics
To Be Published
5DCG
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BU of 5dcg by Molmil
Crystal Structure of WT Apo Human Glutathione Transferase Pi
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Glutathione S-transferase P, ...
Authors:Parker, L.J, Parker, M.W, Morton, C.J.
Deposit date:2015-08-24
Release date:2016-12-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics
To Be Published
5DJM
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BU of 5djm by Molmil
Structure of WT Human Glutathione Transferase in complex with cisplatin in the absence of glutathione.
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Glutathione S-transferase P, PLATINUM (II) ION
Authors:Parker, L.J.
Deposit date:2015-09-02
Release date:2016-11-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A structure-based mechanism of cisplatin resistance mediated by Glutathione Transferase P1-1
Proc.Natl.Acad.Sci.USA, 2019
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