5OPN
Crystal structure of R39Q cN-II mutant
Summary for 5OPN
| Entry DOI | 10.2210/pdb5opn/pdb |
| Related | 5OPK 5OPL 5OPM |
| Descriptor | Cytosolic purine 5'-nucleotidase, GLYCEROL (3 entities in total) |
| Functional Keywords | nucleotidase, relapsed leukemia, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 55847.75 |
| Authors | Hnizda, A.,Pachl, P.,Rezacova, P. (deposition date: 2017-08-10, release date: 2018-06-13, Last modification date: 2024-01-17) |
| Primary citation | Hnizda, A.,Fabry, M.,Moriyama, T.,Pachl, P.,Kugler, M.,Brinsa, V.,Ascher, D.B.,Carroll, W.L.,Novak, P.,Zaliova, M.,Trka, J.,Rezacova, P.,Yang, J.J.,Veverka, V. Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation. Leukemia, 32:1393-1403, 2018 Cited by PubMed: 29535428DOI: 10.1038/s41375-018-0073-5 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
Download full validation report
