5DDL

Crystal Structure of WT Human Glutathione Transferase Pi soaked with a metalloid then back-soaked with glutathione

Summary for 5DDL

Related5DAL 5DAK 5DCG
DescriptorGlutathione S-transferase P, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Di-glutathione-PhenylArsine, ... (7 entities in total)
Functional Keywordstransferase, anti-cancer, organometallic
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm  P09211
Total number of polymer chains2
Total molecular weight49466.19
Authors
Parker, L.J.,Parker, M.W.,Morton, C.J. (deposition date: 2015-08-25, release date: 2016-10-26)
Primary citation
Parker, L.J.,Parker, M.W.,Morton, C.J.,Bocedi, A.,Ascher, D.B.,Aitken, J.B.,Harris, H.H.,Lo Bello, M.,Ricci, G.
Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.98 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.17920.2%0.9%1.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution