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7N85
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BU of 7n85 by Molmil
Inner ring spoke from the isolated yeast NPC
Descriptor: Nucleoporin ASM4, Nucleoporin NIC96, Nucleoporin NSP1, ...
Authors:Akey, C.W, Rout, M.P, Ouch, C, Echevarria, I, Fernandez-Martinez, J, Nudelman, I.
Deposit date:2021-06-13
Release date:2022-01-26
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Comprehensive structure and functional adaptations of the yeast nuclear pore complex.
Cell, 185, 2022
5YVG
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BU of 5yvg by Molmil
Crystal structure of Karyopherin beta2 in complex with FUS(full length)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-11-25
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.05 Å)
Cite:Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018
5YVH
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BU of 5yvh by Molmil
Crystal structure of Karyopherin beta2 in complex with FUS(371-526)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-11-25
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018
5YVI
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BU of 5yvi by Molmil
Crystal structure of Karyopherin beta2 in complex with FUS(456-526)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-11-25
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018
4IFQ
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BU of 4ifq by Molmil
Crystal structure of Saccharomyces cerevisiae NUP192, residues 2 to 960 [ScNup192(2-960)]
Descriptor: IODIDE ION, Nucleoporin NUP192, SULFATE ION
Authors:Sampathkumar, P, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals)
Deposit date:2012-12-14
Release date:2013-02-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure, dynamics, evolution, and function of a major scaffold component in the nuclear pore complex.
Structure, 21, 2013
2FH7
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BU of 2fh7 by Molmil
Crystal structure of the phosphatase domains of human PTP SIGMA
Descriptor: Receptor-type tyrosine-protein phosphatase S
Authors:Alvarado, J, Udupi, R, Smith, D, Koss, J, Wasserman, S.R, Ozyurt, S, Atwell, S, Powell, A, Kearins, M.C, Rooney, I, Maletic, M, Bain, K.T, Freeman, J.C, Russell, M, Thompson, D.A, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-12-23
Release date:2006-01-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
8T9L
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BU of 8t9l by Molmil
Pom34-Pom152 membrane attachment site yeast NPC
Descriptor: Nucleoporin POM152, Nucleoporin POM34
Authors:Akey, C.W, Echeverria, I, Ouch, C, Fernandez-Martinez, J, Rout, M.P.
Deposit date:2023-06-24
Release date:2023-10-11
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Implications of a multiscale structure of the yeast nuclear pore complex.
Mol.Cell, 83, 2023
8TIE
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BU of 8tie by Molmil
Double nuclear outer ring of Nup84-complexes from the yeast NPC
Descriptor: NUP133 isoform 1, NUP145 isoform 1, Nucleoporin NUP120, ...
Authors:Akey, C.W, Echeverria, I, Ouch, C, Fernandez-Martinez, J, Rout, M.P.
Deposit date:2023-07-19
Release date:2023-10-11
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:Implications of a multiscale structure of the yeast nuclear pore complex.
Mol.Cell, 83, 2023
8TJ5
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BU of 8tj5 by Molmil
Inner spoke ring of the yeast NPC
Descriptor: Nucleoporin 59, Nucleoporin NIC96, Nucleoporin NSP1, ...
Authors:Akey, C.W, Echeverria, I, Ouch, C, Fernandez-Martinez, J, Rout, M.P.
Deposit date:2023-07-20
Release date:2023-10-11
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Implications of a multiscale structure of the yeast nuclear pore complex.
Mol.Cell, 83, 2023
8SXA
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BU of 8sxa by Molmil
Inward-facing wide conformation of bovine multidrug resistance protein 4 (MRP4) in MSP lipid nanodisc
Descriptor: Multidrug resistance-associated protein 4
Authors:Pourmal, S, Stroud, R.M.
Deposit date:2023-05-20
Release date:2024-01-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SX8
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BU of 8sx8 by Molmil
Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E1 in MSP lipid nanodisc
Descriptor: 7-[(1R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid, Multidrug resistance-associated protein 4
Authors:Pourmal, S, Stroud, R.M.
Deposit date:2023-05-20
Release date:2024-01-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
2ER7
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BU of 2er7 by Molmil
X-RAY ANALYSES OF ASPARTIC PROTEINASES.III. THREE-DIMENSIONAL STRUCTURE OF ENDOTHIAPEPSIN COMPLEXED WITH A TRANSITION-STATE ISOSTERE INHIBITOR OF RENIN AT 1.6 ANGSTROMS RESOLUTION
Descriptor: ENDOTHIAPEPSIN, SULFATE ION, TRANSITION-STATE ISOSTERE INHIBITOR OF RENIN
Authors:Veerapandian, B, Cooper, J.B, Szelke, M, Blundell, T.L.
Deposit date:1990-11-12
Release date:1991-01-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-ray analyses of aspartic proteinases. III Three-dimensional structure of endothiapepsin complexed with a transition-state isostere inhibitor of renin at 1.6 A resolution.
J.Mol.Biol., 216, 1990
2G59
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BU of 2g59 by Molmil
Crystal Structure of the Catalytic Domain of Protein Tyrosine Phosphatase from Homo sapiens
Descriptor: PHOSPHATE ION, Receptor-type tyrosine-protein phosphatase O
Authors:Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-02-22
Release date:2006-03-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
4U1D
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BU of 4u1d by Molmil
Structure of the PCI domain of translation initiation factor eIF3a
Descriptor: Eukaryotic translation initiation factor 3 subunit A
Authors:Erzberger, J.P, Schaefer, T, Ban, N.
Deposit date:2014-07-15
Release date:2014-09-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Molecular Architecture of the 40SeIF1eIF3 Translation Initiation Complex.
Cell, 158, 2014
4U1C
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BU of 4u1c by Molmil
Crystal structure of the eIF3a/eIF3c PCI-domain heterodimer
Descriptor: Eukaryotic translation initiation factor 3 subunit A, Eukaryotic translation initiation factor 3 subunit C
Authors:Erzberger, J.P, Schaefer, T, Ban, N.
Deposit date:2014-07-15
Release date:2014-09-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular Architecture of the 40SeIF1eIF3 Translation Initiation Complex.
Cell, 158, 2014
4U1E
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BU of 4u1e by Molmil
Crystal structure of the eIF3b-CTD/eIF3i/eIF3g-NTD translation initiation complex
Descriptor: Eukaryotic translation initiation factor 3 subunit B, Eukaryotic translation initiation factor 3 subunit G, Eukaryotic translation initiation factor 3 subunit I
Authors:Zhang, S, Erzberger, J.P, Schaefer, T, Ban, N.
Deposit date:2014-07-15
Release date:2014-09-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular Architecture of the 40SeIF1eIF3 Translation Initiation Complex.
Cell, 158, 2014
4U1F
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BU of 4u1f by Molmil
Crystal structure of middle domain of eukaryotic translation initiation factor eIF3b
Descriptor: Eukaryotic translation initiation factor 3 subunit B
Authors:Zhang, S, Erzberger, J.P, Schaefer, T, Ban, N.
Deposit date:2014-07-15
Release date:2014-09-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular Architecture of the 40SeIF1eIF3 Translation Initiation Complex.
Cell, 158, 2014
4V5Z
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BU of 4v5z by Molmil
Structure of a mammalian 80S ribosome obtained by docking homology models of the RNA and proteins into an 8.7 A cryo-EM map
Descriptor: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S Ribosomal protein RACK1, ...
Authors:Chandramouli, P, Akey, C.W.
Deposit date:2008-03-27
Release date:2014-07-09
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Structure of the Mammalian 80S Ribosome at 8.7 A Resolution
Structure, 16, 2008
7LTO
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BU of 7lto by Molmil
Nse5-6 complex
Descriptor: Non-structural maintenance of chromosome element 5, Ubiquitin-like protein SMT3,DNA repair protein KRE29 chimera
Authors:Yu, Y, Li, S.B, Zheng, S, Tangy, S, Koyi, C, Wan, B.B, Kung, H.H, Andrej, S, Alex, K, Patel, D.J, Zhao, X.L.
Deposit date:2021-02-19
Release date:2021-05-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Integrative analysis reveals unique structural and functional features of the Smc5/6 complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
4DS7
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BU of 4ds7 by Molmil
Crystal structure of yeast calmodulin bound to the C-terminal fragment of spindle pole body protein Spc110
Descriptor: Calmodulin, GLYCEROL, STRONTIUM ION, ...
Authors:Klenchin, V.A, Rayment, I.
Deposit date:2012-02-18
Release date:2012-03-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling.
Mol.Biol.Cell, 28, 2017
8SXB
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BU of 8sxb by Molmil
Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E2 in MSP lipid nanodisc
Descriptor: (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Multidrug resistance-associated protein 4 isoform X1
Authors:Pourmal, S, Stroud, R.M.
Deposit date:2023-05-20
Release date:2024-01-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SWN
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BU of 8swn by Molmil
Bovine multidrug resistance protein 4 (MRP4) E1202Q mutant bound to ATP in MSP lipid nanodisc
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP binding cassette subfamily C member 4, MAGNESIUM ION, ...
Authors:Pourmal, S, Stroud, R.M.
Deposit date:2023-05-19
Release date:2024-01-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SX7
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BU of 8sx7 by Molmil
Bovine multidrug resistance protein 4 (MRP4) bound to DHEA-S in MSP lipid nanodisc
Descriptor: 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, Multidrug resistance-associated protein 4
Authors:Pourmal, S, Stroud, R.M.
Deposit date:2023-05-20
Release date:2024-01-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SX9
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BU of 8sx9 by Molmil
Inward-facing narrow conformation of bovine multidrug resistance protein 4 (MRP4) in MSP lipid nanodisc
Descriptor: Multidrug resistance-associated protein 4
Authors:Pourmal, S, Stroud, R.M.
Deposit date:2023-05-20
Release date:2024-01-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
3HD6
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BU of 3hd6 by Molmil
Crystal Structure of the Human Rhesus Glycoprotein RhCG
Descriptor: Ammonium transporter Rh type C, octyl beta-D-glucopyranoside
Authors:Gruswitz, F, Chaudhary, S, Ho, J.D, Pezeshki, B, Ho, C.-M, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP)
Deposit date:2009-05-06
Release date:2009-09-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Function of human Rh based on structure of RhCG at 2.1 A.
Proc.Natl.Acad.Sci.USA, 107, 2010

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