8SXB
Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E2 in MSP lipid nanodisc
Summary for 8SXB
| Entry DOI | 10.2210/pdb8sxb/pdb |
| EMDB information | 40830 |
| Descriptor | Multidrug resistance-associated protein 4 isoform X1, (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid (3 entities in total) |
| Functional Keywords | abc transporter, multidrug resistance-associated protein, membrane protein, transport protein |
| Biological source | Bos indicus (zebu cattle) |
| Total number of polymer chains | 1 |
| Total formula weight | 149939.76 |
| Authors | Pourmal, S.,Stroud, R.M. (deposition date: 2023-05-20, release date: 2024-01-17, Last modification date: 2024-03-13) |
| Primary citation | Pourmal, S.,Green, E.,Bajaj, R.,Chemmama, I.E.,Knudsen, G.M.,Gupta, M.,Sali, A.,Cheng, Y.,Craik, C.S.,Kroetz, D.L.,Stroud, R.M. Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38216659DOI: 10.1038/s41594-023-01176-4 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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