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3CFC
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BU of 3cfc by Molmil
High-resolution structure of blue fluorescent antibody EP2-19G2
Descriptor: BLUE FLUORESCENT ANTIBODY EP2-19G2-IGG2B HEAVY CHAIN, BLUE FLUORESCENT ANTIBODY EP2-19G2-KAPPA LIGHT CHAIN, GLYCEROL
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2008-03-03
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
3CN0
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BU of 3cn0 by Molmil
Human transthyretin (TTR) in complex with 3,5-Dimethyl-4-hydroxystilbene
Descriptor: 2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2008-03-24
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
J.Med.Chem., 51, 2008
3RG1
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BU of 3rg1 by Molmil
Crystal structure of the RP105/MD-1 complex
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, CD180 molecule, LY86 protein, ...
Authors:Yoon, S.I, Hong, M, Wilson, I.A.
Deposit date:2011-04-07
Release date:2011-08-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:An unusual dimeric structure and assembly for TLR4 regulator RP105-MD-1.
Nat.Struct.Mol.Biol., 18, 2011
1THZ
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BU of 1thz by Molmil
Crystal Structure of Avian AICAR Transformylase in Complex with a Novel Inhibitor Identified by Virtual Ligand Screening
Descriptor: 2-{(E)-[5-HYDROXY-3-METHYL-1-(2-METHYL-4-SULFOPHENYL)-1H-PYRAZOL-4-YL]DIAZENYL}-4-SULFOBENZOIC ACID, Bifunctional purine biosynthesis protein PURH, POTASSIUM ION
Authors:Xu, L, Li, C, Olson, A.J, Wilson, I.A.
Deposit date:2004-06-01
Release date:2004-09-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of avian aminoimidazole-4-carboxamide ribonucleotide transformylase in complex with a novel non-folate inhibitor identified by virtual ligand screening.
J.Biol.Chem., 279, 2004
3SDY
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BU of 3sdy by Molmil
Crystal Structure of Broadly Neutralizing Antibody CR8020 Bound to the Influenza A H3 Hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8020, Heavy Chain, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2011-06-09
Release date:2011-07-20
Last modified:2021-04-07
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A highly conserved neutralizing epitope on group 2 influenza A viruses.
Science, 333, 2011
3CN4
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BU of 3cn4 by Molmil
Human transthyretin (TTR) in complex with N-(3,5-Dibromo-4-hydroxyphenyl)benzamide
Descriptor: N-(3,5-dibromo-4-hydroxyphenyl)benzamide, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2008-03-24
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
J.Med.Chem., 51, 2008
3CN2
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BU of 3cn2 by Molmil
Human transthyretin (TTR) in complex with 3,5-Dibromo-4-hydroxybiphenyl
Descriptor: 3,5-dibromobiphenyl-4-ol, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2008-03-24
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
J.Med.Chem., 51, 2008
3CUP
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BU of 3cup by Molmil
Crystal structure of the MHC class II molecule I-Ag7 in complex with the peptide GAD221-235
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, H-2 class II histocompatibility antigen, ...
Authors:Corper, A.L, Yoshida, K, Teyton, L, Wilson, I.A.
Deposit date:2008-04-16
Release date:2009-04-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Crystal structure of the MHC class II molecule I-Ag7 in complex with the peptide GAD221-235
To be Published
3CFD
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BU of 3cfd by Molmil
Purple-fluorescent antibody EP2-25C10 in complex with its stilbene hapten
Descriptor: 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID, GLYCEROL, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-IGG2B HEAVY CHAIN, ...
Authors:Debler, E.W, Heine, A, Wilson, I.A.
Deposit date:2008-03-03
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
3Q1S
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BU of 3q1s by Molmil
HIV-1 neutralizing antibody Z13e1 in complex with epitope display protein
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Interleukin-22, ...
Authors:Stanfield, R.L, Julien, J.-P, Pejchal, R, Gach, J.S, Zwick, M.B, Wilson, I.A.
Deposit date:2010-12-17
Release date:2011-11-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure-Based Design of a Protein Immunogen that Displays an HIV-1 gp41 Neutralizing Epitope.
J.Mol.Biol., 414, 2011
3R06
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BU of 3r06 by Molmil
Crystal structure of anti-mouse CD3epsilon antibody 2C11 Fab fragment
Descriptor: anti-mouse CD3epsilon antibody 2C11 Fab heavy chain, anti-mouse CD3epsilon antibody 2C11 Fab light chain
Authors:Shore, D.A, Zhu, X, Wilson, I.A.
Deposit date:2011-03-07
Release date:2012-01-25
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:T cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements.
J.Biol.Chem., 287, 2012
3CFE
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BU of 3cfe by Molmil
Crystal structure of purple-fluorescent antibody EP2-25C10
Descriptor: GLYCEROL, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-IGG2B HEAVY CHAIN, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-KAPPA LIGHT CHAIN, ...
Authors:Debler, E.W, Heine, A, Wilson, I.A.
Deposit date:2008-03-03
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
3T0W
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BU of 3t0w by Molmil
Fluorogen activating protein M8VL in complex with dimethylindole red
Descriptor: 1-(3-sulfopropyl)-4-[(1E,3E)-3-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)prop-1-en-1-yl]quinolinium, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, ...
Authors:Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P.
Deposit date:2011-07-20
Release date:2012-03-21
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.
Biochemistry, 51, 2012
3CFK
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BU of 3cfk by Molmil
Crystal structure of catalytic elimination antibody 34E4, triclinic crystal form
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, CATALYTIC ANTIBODY FAB 34E4 HEAVY CHAIN,Uncharacterized protein, ...
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2008-03-04
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Conformational isomerism can limit antibody catalysis.
J.Biol.Chem., 283, 2008
3CN3
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BU of 3cn3 by Molmil
Human transthyretin (TTR) in complex with 1,3-Dibromo-2-hydroxy-5-phenoxybenzene
Descriptor: 2,6-dibromo-4-phenoxyphenol, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2008-03-24
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
J.Med.Chem., 51, 2008
3CFB
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BU of 3cfb by Molmil
High-resolution structure of blue fluorescent antibody EP2-19G2 in complex with stilbene hapten at 100K
Descriptor: 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID, BLUE FLUORESCENT ANTIBODY EP2-19G2-IGG2B HEAVY CHAIN, BLUE FLUORESCENT ANTIBODY EP2-19G2-KAPPA LIGHT CHAIN, ...
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2008-03-03
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
3CN1
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BU of 3cn1 by Molmil
Human transthyretin (TTR) in complex with 3,5-Dibromo-4-hydroxystilbene
Descriptor: 2,6-dibromo-4-[(E)-2-phenylethenyl]phenol, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2008-03-24
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
J.Med.Chem., 51, 2008
3FN0
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BU of 3fn0 by Molmil
Crystal structure of HIV-1 neutralizing human Fab Z13e1 in complex with a 12-residue peptide containing the Z13e1 epitope on gp41
Descriptor: Envelope polyprotein gp160, Fab Z13e1
Authors:Pejchal, R, Wilson, I.A, Zwick, M.B.
Deposit date:2008-12-22
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies.
J.Virol., 83, 2009
3FO9
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BU of 3fo9 by Molmil
Crystal structure of aldolase antibody 33F12 Fab' in complex with hapten 1,3-diketone
Descriptor: 5-{[4-(5-methyl-3-oxohex-4-en-1-yl)phenyl]amino}-5-oxopentanoic acid, Immunoglobulin IGG2A - heavy chain, Immunoglobulin IGG2A - light chain
Authors:Zhu, X, Wilson, I.A.
Deposit date:2008-12-29
Release date:2009-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Direct observation of an enamine intermediate in amine catalysis
J.Am.Chem.Soc., 131, 2009
3FO2
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BU of 3fo2 by Molmil
Crystal structure of hapten complex of catalytic elimination antibody 13G5 (Glu(L39)Gln mutant)
Descriptor: 5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID, Catalytic antibody Fab 13G5 IgG2b heavy chain chimera, Catalytic antibody Fab 13G5 kappa light chain chimera
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2008-12-27
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.
Proc.Natl.Acad.Sci.USA, 106, 2009
3FO1
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BU of 3fo1 by Molmil
Crystal structure of hapten complex of catalytic elimination antibody 13G5 (Glu(L39)Ala mutant)
Descriptor: 5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID, Catalytic antibody Fab 13G5 IgG2b heavy chain chimera, Catalytic antibody Fab 13G5 kappa light chain chimera
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2008-12-27
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.
Proc.Natl.Acad.Sci.USA, 106, 2009
3T0X
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BU of 3t0x by Molmil
Fluorogen Activating Protein M8VLA4(S55P) in complex with dimethylindole red
Descriptor: 1,2-ETHANEDIOL, 1-(3-sulfopropyl)-4-[(1E,3E)-3-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)prop-1-en-1-yl]quinolinium, Immunoglobulin variable lambda domain M8VLA4(S55P), ...
Authors:Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P.
Deposit date:2011-07-20
Release date:2012-03-21
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.
Biochemistry, 51, 2012
3FO0
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BU of 3fo0 by Molmil
Crystal structure of hapten complex of catalytic elimination antibody 13G5 (wild-type)
Descriptor: 5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID, Catalytic antibody Fab 13G5 IgG2b heavy chain chimera, Catalytic antibody Fab 13G5 kappa light chain chimera, ...
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2008-12-27
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.
Proc.Natl.Acad.Sci.USA, 106, 2009
3T0V
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BU of 3t0v by Molmil
Unliganded fluorogen activating protein M8VL
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ...
Authors:Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P.
Deposit date:2011-07-20
Release date:2012-03-21
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.
Biochemistry, 51, 2012
3QQO
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BU of 3qqo by Molmil
Crystal structure of HA2 R106H mutant of H2 hemagglutinin, acidic pH form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
Authors:Xu, R, Wilson, I.A.
Deposit date:2011-02-15
Release date:2011-03-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Characterization of an Early Fusion Intermediate of Influenza Virus Hemagglutinin.
J.Virol., 85, 2011

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