3FO9

Crystal structure of aldolase antibody 33F12 Fab' in complex with hapten 1,3-diketone

Summary for 3FO9

• Entry DOI: 10.2210/pdb3fo9/pdb
• Related: 1axt
• Descriptor: Immunoglobulin IGG2A - light chain, Immunoglobulin IGG2A - heavy chain, 5-{[4-(5-methyl-3-oxohex-4-en-1-yl)phenyl]amino}-5-oxopentanoic acid, ... (4 entities in total)
• Functional Keywords: aldolase antibody, enamine intermediate, amine catalysis, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 4
• Total formula weight: 96580.10

Authors

Zhu, X.,Wilson, I.A. (deposition date: 2008-12-29, release date: 2009-12-22, Last modification date: 2023-09-06)

• Primary citation: Zhu, X.,Tanaka, F.,Lerner, R.A.,Barbas, C.F.,Wilson, I.A.; Direct observation of an enamine intermediate in amine catalysis; J.Am.Chem.Soc., 131:18206-18207, 2009; PubMed: 19968282; DOI: 10.1021/ja907271a

Experimental method

X-RAY DIFFRACTION (1.9 Å)