3T0X

Fluorogen Activating Protein M8VLA4(S55P) in complex with dimethylindole red

Summary for 3T0X

• Entry DOI: 10.2210/pdb3t0x/pdb
• Related: 3T0V 3T0W
• Descriptor: Immunoglobulin variable lambda domain M8VLA4(S55P), 1-(3-sulfopropyl)-4-[(1E,3E)-3-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)prop-1-en-1-yl]quinolinium, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: immunoglobulin fold, fluorogen activation, dimethylindole red, dye-binding protein
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 27408.63

Authors

Stanfield, R.,Senutovitch, N.,Bhattacharyya, S.,Rule, G.,Wilson, I.A.,Armitage, B.,Waggoner, A.S.,Berget, P. (deposition date: 2011-07-20, release date: 2012-03-21, Last modification date: 2019-12-25)

• Primary citation: Senutovitch, N.,Stanfield, R.L.,Bhattacharyya, S.,Rule, G.S.,Wilson, I.A.,Armitage, B.A.,Waggoner, A.S.,Berget, P.B.; A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.; Biochemistry, 51:2471-2485, 2012; PubMed: 22390683; DOI: 10.1021/bi201422g

Experimental method

X-RAY DIFFRACTION (1.96 Å)