3FN0

Crystal structure of HIV-1 neutralizing human Fab Z13e1 in complex with a 12-residue peptide containing the Z13e1 epitope on gp41

Summary for 3FN0

• Entry DOI: 10.2210/pdb3fn0/pdb
• Descriptor: Fab Z13e1, Envelope polyprotein gp160, ... (4 entities in total)
• Functional Keywords: z13e1, z13, hiv, env, gp41, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 49074.92

Authors

Pejchal, R.,Wilson, I.A.,Zwick, M.B. (deposition date: 2008-12-22, release date: 2009-06-23, Last modification date: 2023-09-06)

• Primary citation: Pejchal, R.,Gach, J.S.,Brunel, F.M.,Cardoso, R.M.,Stanfield, R.L.,Dawson, P.E.,Burton, D.R.,Zwick, M.B.,Wilson, I.A.; A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies.; J.Virol., 83:8451-8462, 2009; PubMed: 19515770; DOI: 10.1128/JVI.00685-09

Experimental method

X-RAY DIFFRACTION (1.8 Å)