7QJ4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qj4 by Molmil](/molmil-images/mine/7qj4) | |
7QJB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qjb by Molmil](/molmil-images/mine/7qjb) | |
7QJC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qjc by Molmil](/molmil-images/mine/7qjc) | |
7QJ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qj0 by Molmil](/molmil-images/mine/7qj0) | |
7QJ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qj8 by Molmil](/molmil-images/mine/7qj8) | |
7QVE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qve by Molmil](/molmil-images/mine/7qve) | Spinach 20S proteasome | Descriptor: | Proteasome subunit alpha type, Proteasome subunit alpha type-3, Proteasome subunit beta, ... | Authors: | Kandolf, S, Grishkovskaya, I, Meinhart, A, Haselbach, D. | Deposit date: | 2022-01-21 | Release date: | 2022-05-25 | Last modified: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of the plant 26S proteasome. Plant Commun., 3, 2022
|
|
5HH4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hh4 by Molmil](/molmil-images/mine/5hh4) | |
5HH6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hh6 by Molmil](/molmil-images/mine/5hh6) | |
5OR6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5or6 by Molmil](/molmil-images/mine/5or6) | Crystal structures of PYR1/HAB1 in complex with synthetic analogues of Abscisic Acid | Descriptor: | (~{E})-3-(trifluoromethyl)-5-[(1~{S})-2,6,6-trimethyl-1-oxidanyl-4-oxidanylidene-cyclohex-2-en-1-yl]pent-2-en-4-ynoic acid, Abscisic acid receptor PYR1, MANGANESE (II) ION, ... | Authors: | Freigang, J. | Deposit date: | 2017-08-15 | Release date: | 2018-06-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Insights into the in Vitro and in Vivo SAR of Abscisic Acid - Exploring Unprecedented Variations of the Side Chain via Cross-Coupling-Mediated Syntheses Eur.J.Org.Chem., 2018
|
|
1E1Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1e1y by Molmil](/molmil-images/mine/1e1y) | Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site | Descriptor: | 2-(2-CHLORO-PHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYL-PIPERIDIN-4-YL)-4H-BENZOPYRAN-4-ONE, GLYCOGEN PHOSPHORYLASE, MUSCLE FORM, ... | Authors: | Oikonomakos, N.G, Zographos, S.E, Skamnaki, V.T, Tsitsanou, K.E, Johnson, L.N. | Deposit date: | 2000-05-11 | Release date: | 2000-05-17 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Flavopiridol Inhibits Glycogen Phosphorylase by Binding at the Inhibitor Site J.Biol.Chem., 275, 2000
|
|
7OSE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ose by Molmil](/molmil-images/mine/7ose) | cytochrome bd-II type oxidase with bound aurachin D | Descriptor: | Aurachin D, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Cytochrome bd-II ubiquinol oxidase subunit 1, ... | Authors: | Grauel, A, Kaegi, J, Rasmussen, T, Wohlwend, D, Boettcher, B, Friedrich, T. | Deposit date: | 2021-06-08 | Release date: | 2021-11-17 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of Escherichia coli cytochrome bd-II type oxidase with bound aurachin D. Nat Commun, 12, 2021
|
|
8AT2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8at2 by Molmil](/molmil-images/mine/8at2) | Structure of the augmin TIII subcomplex | Descriptor: | HAUS augmin like complex subunit 4 L homeolog, HAUS augmin-like complex subunit 1, HAUS augmin-like complex subunit 3, ... | Authors: | Zupa, E, Pfeffer, S. | Deposit date: | 2022-08-22 | Release date: | 2022-09-28 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | The augmin complex architecture reveals structural insights into microtubule branching. Nat Commun, 13, 2022
|
|
8AT3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8at3 by Molmil](/molmil-images/mine/8at3) | Structure of the augmin holocomplex in open conformation | Descriptor: | HAUS augmin like complex subunit 2 L homeolog, HAUS augmin like complex subunit 4 L homeolog, HAUS augmin like complex subunit 6 L homeolog, ... | Authors: | Zupa, E, Pfeffer, S. | Deposit date: | 2022-08-22 | Release date: | 2022-09-28 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (33 Å) | Cite: | The augmin complex architecture reveals structural insights into microtubule branching. Nat Commun, 13, 2022
|
|
8AT4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8at4 by Molmil](/molmil-images/mine/8at4) | Structure of the augmin holocomplex in closed conformation | Descriptor: | HAUS augmin like complex subunit 2 L homeolog, HAUS augmin like complex subunit 4 L homeolog, HAUS augmin like complex subunit 6 L homeolog, ... | Authors: | Zupa, E, Pfeffer, S. | Deposit date: | 2022-08-22 | Release date: | 2022-09-28 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (33 Å) | Cite: | The augmin complex architecture reveals structural insights into microtubule branching. Nat Commun, 13, 2022
|
|
7QKS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qks by Molmil](/molmil-images/mine/7qks) | |
7QKR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qkr by Molmil](/molmil-images/mine/7qkr) | Cryo-EM structure of ABC transporter STE6-2p from Pichia pastoris with Verapamil at 3.2 A resolution | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, Dexverapamil, MAGNESIUM ION, ... | Authors: | Schleker, E.S.M, Reinhart, C. | Deposit date: | 2021-12-18 | Release date: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural and functional investigation of ABC transporter STE6-2p from Pichia pastoris reveals unexpected interaction with sterol molecules. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
1M9I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1m9i by Molmil](/molmil-images/mine/1m9i) | |
6HGO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hgo by Molmil](/molmil-images/mine/6hgo) | Crystal Structure of human IL-17F | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17F, ... | Authors: | Rondeau, J.M, Goepfert, A. | Deposit date: | 2018-08-23 | Release date: | 2019-11-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling. Immunity, 52, 2020
|
|
1WUT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wut by Molmil](/molmil-images/mine/1wut) | Acyl Ureas as Human Liver Glycogen Phosphorylase Inhibitors for the Treatment of Type 2 Diabetes | Descriptor: | 7-[2,6-DICHLORO-4-({[(2-CHLOROBENZOYL)AMINO]CARBONYL}AMINO)PHENOXY]HEPTANOIC ACID, Glycogen phosphorylase, muscle form, ... | Authors: | Klabunde, T, Wendt, K.U, Kadereit, D, Brachvogel, V, Burger, H.-J, Herling, A.W, Oikonomakos, N.G, Kosmopoulou, M.N, Schmoll, D, Sarubbi, E, von Roedern, E, Schonafinger, K, Defossa, E. | Deposit date: | 2004-12-08 | Release date: | 2005-12-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs Protein Sci., 14, 2005
|
|
6ODH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6odh by Molmil](/molmil-images/mine/6odh) | BH3 domain swapped dimer of a BAK fragment | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bcl-2 homologous antagonist/killer, DI(HYDROXYETHYL)ETHER, ... | Authors: | Liu, L.-K. | Deposit date: | 2019-03-26 | Release date: | 2020-10-07 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A BAK fragment that binds mitochondrial lipids and releases cytochrome c To Be Published
|
|
1IEZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1iez by Molmil](/molmil-images/mine/1iez) | Solution Structure of 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase of Riboflavin Biosynthesis | Descriptor: | 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase | Authors: | Kelly, M.J.S, Ball, L.J, Kuhne, R, Bacher, A, Oschkinat, H. | Deposit date: | 2001-04-11 | Release date: | 2001-11-07 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The NMR structure of the 47-kDa dimeric enzyme 3,4-dihydroxy-2-butanone-4-phosphate synthase and ligand binding studies reveal the location of the active site. Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
8HI9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hi9 by Molmil](/molmil-images/mine/8hi9) | SARS-CoV-2 3CL protease (3CLpro) in complex with Robinetin | Descriptor: | 3,7-bis(oxidanyl)-2-[3,4,5-tris(oxidanyl)phenyl]chromen-4-one, 3C-like proteinase nsp5 | Authors: | Su, H.X, Xie, H, Li, M.J, Xu, Y.C. | Deposit date: | 2022-11-19 | Release date: | 2023-10-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Discovery of Polyphenolic Natural Products as SARS-CoV-2 M pro Inhibitors for COVID-19. Pharmaceuticals, 16, 2023
|
|
6HGA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hga by Molmil](/molmil-images/mine/6hga) | |
6HG4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hg4 by Molmil](/molmil-images/mine/6hg4) | |
7NUS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nus by Molmil](/molmil-images/mine/7nus) | |