1IEZ

Solution Structure of 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase of Riboflavin Biosynthesis

Summary for 1IEZ

• Entry DOI: 10.2210/pdb1iez/pdb
• Related: 1g57 1g58
• Descriptor: 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase (1 entity in total)
• Functional Keywords: dihydroxybutanone phosphate synthase, riboflavin biosynthesis, skeletal rearrangement, antimicrobial target, structure based design, isomerase
• Biological source: Escherichia coli
• Cellular location: Cell membrane; Peripheral membrane protein (Potential): P0A7J0
• Total number of polymer chains: 1
• Total formula weight: 23378.46

Authors

Kelly, M.J.S.,Ball, L.J.,Kuhne, R.,Bacher, A.,Oschkinat, H. (deposition date: 2001-04-11, release date: 2001-11-07, Last modification date: 2011-07-13)

• Primary citation: Kelly, M.J.,Ball, L.J.,Krieger, C.,Yu, Y.,Fischer, M.,Schiffmann, S.,Schmieder, P.,Kuhne, R.,Bermel, W.,Bacher, A.,Richter, G.,Oschkinat, H.; The NMR structure of the 47-kDa dimeric enzyme 3,4-dihydroxy-2-butanone-4-phosphate synthase and ligand binding studies reveal the location of the active site.; Proc.Natl.Acad.Sci.USA, 98:13025-13030, 2001; PubMed: 11687623; DOI: 10.1073/pnas.231323598

Experimental method

SOLUTION NMR