8HI9

SARS-CoV-2 3CL protease (3CLpro) in complex with Robinetin

Summary for 8HI9

• Entry DOI: 10.2210/pdb8hi9/pdb
• Descriptor: 3C-like proteinase nsp5, 3,7-bis(oxidanyl)-2-[3,4,5-tris(oxidanyl)phenyl]chromen-4-one (3 entities in total)
• Functional Keywords: mpro, viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 68255.57

Authors

Su, H.X.,Xie, H.,Li, M.J.,Xu, Y.C. (deposition date: 2022-11-19, release date: 2023-10-25, Last modification date: 2023-11-01)

• Primary citation: Kruger, N.,Kronenberger, T.,Xie, H.,Rocha, C.,Pohlmann, S.,Su, H.,Xu, Y.,Laufer, S.A.,Pillaiyar, T.; Discovery of Polyphenolic Natural Products as SARS-CoV-2 M pro Inhibitors for COVID-19.; Pharmaceuticals, 16:-, 2023; PubMed: 37259339; DOI: 10.3390/ph16020190

Experimental method

X-RAY DIFFRACTION (2.28 Å)