6E83
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6OIE
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3OD5
| Crystal structure of active caspase-6 bound with Ac-VEID-CHO | Descriptor: | CACODYLATE ION, Caspase-6, peptide aldehyde inhibitor AC-VEID-CHO | Authors: | Wang, X.-J, Liu, X, Wang, K.-T, Cao, Q, Su, X.-D. | Deposit date: | 2010-08-11 | Release date: | 2010-10-27 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage self-activation Embo Rep., 11, 2010
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5IQL
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5VAE
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5VAF
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6VK3
| CryoEM structure of Hrd3/Yos9 complex | Descriptor: | Hrd3, Protein OS-9 homolog | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2020-05-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6VJZ
| CryoEM structure of Hrd1-Usa1/Der1/Hrd3 complex of the expected topology | Descriptor: | Degradation in the endoplasmic reticulum protein 1, ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3, ... | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6VK1
| CryoEM structure of Hrd1/Hrd3 part from Hrd1-Usa1/Der1/Hrd3 complex | Descriptor: | ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3 | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6VK0
| CryoEM structure of Hrd1-Usa1/Der1/Hrd3 of the flipped topology | Descriptor: | Degradation in the endoplasmic reticulum protein 1, ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3, ... | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6VJY
| Cryo-EM structure of Hrd1/Hrd3 monomer | Descriptor: | ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3 | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6XKC
| Crystal structure of E3 ligase | Descriptor: | Protein fem-1 homolog C | Authors: | Yan, X, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Dong, C, Structural Genomics Consortium (SGC) | Deposit date: | 2020-06-26 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Molecular basis for ubiquitin ligase CRL2 FEM1C -mediated recognition of C-degron. Nat.Chem.Biol., 17, 2021
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6DS6
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3L8A
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7XYT
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7JYA
| Crystal structure of E3 ligase in complex with peptide | Descriptor: | ASN-ARG-ARG-ARG-ARG-TRP-ARG-GLU-ARG-GLN-ARG, Protein fem-1 homolog C, UNKNOWN ATOM OR ION | Authors: | Yan, X, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Dong, C, Structural Genomics Consortium (SGC) | Deposit date: | 2020-08-30 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Molecular basis for ubiquitin ligase CRL2 FEM1C -mediated recognition of C-degron. Nat.Chem.Biol., 17, 2021
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8J4A
| Crystal structure of OY phytoplasma SAP05 in complex with AtRPN10 | Descriptor: | 26S proteasome non-ATPase regulatory subunit 4 homolog, Sequence-variable mosaic (SVM) signal sequence domain-containing protein | Authors: | Dong, C, Yan, X, Yuan, X. | Deposit date: | 2023-04-19 | Release date: | 2024-02-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Molecular basis of SAP05-mediated ubiquitin-independent proteasomal degradation of transcription factors. Nat Commun, 15, 2024
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8J49
| Crystal structure of OY phytoplasma SAP05 in complex with AtSPL5 | Descriptor: | Sequence-variable mosaic (SVM) signal sequence domain-containing protein, Squamosa promoter-binding-like protein 5, ZINC ION | Authors: | Dong, C, Yan, X, Yuan, X. | Deposit date: | 2023-04-19 | Release date: | 2024-02-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Molecular basis of SAP05-mediated ubiquitin-independent proteasomal degradation of transcription factors. Nat Commun, 15, 2024
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8J4B
| Crystal structure of OY phytoplasma SAP05 in complex with AtSPL13 | Descriptor: | Sequence-variable mosaic (SVM) signal sequence domain-containing protein, Squamosa promoter-binding-like protein 13A, ZINC ION | Authors: | Dong, C, Yan, X, Yuan, X. | Deposit date: | 2023-04-19 | Release date: | 2024-02-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis of SAP05-mediated ubiquitin-independent proteasomal degradation of transcription factors. Nat Commun, 15, 2024
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8J48
| Crystal structure of OY phytoplasma SAP05 in complex with AtGATA18 | Descriptor: | GATA transcription factor 18, Sequence-variable mosaic (SVM) signal sequence domain-containing protein, ZINC ION | Authors: | Dong, C, Yan, X, Yuan, X. | Deposit date: | 2023-04-19 | Release date: | 2024-02-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Molecular basis of SAP05-mediated ubiquitin-independent proteasomal degradation of transcription factors. Nat Commun, 15, 2024
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7Y3B
| Crystal structure of TRIM7 bound to GN1 | Descriptor: | E3 ubiquitin-protein ligase TRIM7,TRIM7-GN1 | Authors: | Dong, C, Yan, X. | Deposit date: | 2022-06-10 | Release date: | 2022-08-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7. Proc.Natl.Acad.Sci.USA, 119, 2022
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7Y3C
| Crystal structure of TRIM7 bound to RACO-1 | Descriptor: | E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-RACO-1 | Authors: | Dong, C, Yan, X. | Deposit date: | 2022-06-10 | Release date: | 2022-08-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7. Proc.Natl.Acad.Sci.USA, 119, 2022
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7Y3A
| Crystal structure of TRIM7 bound to 2C | Descriptor: | E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-2C | Authors: | Dong, C, Yan, X. | Deposit date: | 2022-06-10 | Release date: | 2022-08-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7. Proc.Natl.Acad.Sci.USA, 119, 2022
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7XYX
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7XYU
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