3OD5
Crystal structure of active caspase-6 bound with Ac-VEID-CHO
Summary for 3OD5
Entry DOI | 10.2210/pdb3od5/pdb |
Related | 3NR2 |
Related PRD ID | PRD_000976 |
Descriptor | Caspase-6, peptide aldehyde inhibitor AC-VEID-CHO, CACODYLATE ION, ... (4 entities in total) |
Functional Keywords | caspase domain, apoptotic protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P55212 |
Total number of polymer chains | 4 |
Total formula weight | 66174.27 |
Authors | Wang, X.-J.,Liu, X.,Wang, K.-T.,Cao, Q.,Su, X.-D. (deposition date: 2010-08-11, release date: 2010-10-27, Last modification date: 2023-12-06) |
Primary citation | Wang, X.-J.,Cao, Q.,Liu, X.,Wang, K.-T.,Mi, W.,Zhang, Y.,Li, L.-F.,Leblanc, A.C.,Su, X.-D. Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage self-activation Embo Rep., 11:841-847, 2010 Cited by PubMed: 20890311DOI: 10.1038/embor.2010.141 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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