3OD5

Crystal structure of active caspase-6 bound with Ac-VEID-CHO

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Caspase-6	polymer	278	32054.6	2	UniProt (P55212) Pfam (PF00656) In PDB	Homo sapiens (human)	CASP-6, Apoptotic protease Mch-2, Caspase-6 subunit p18, Caspase-6 subunit p11
2	C, D	peptide aldehyde inhibitor AC-VEID-CHO	polymer	5	484.5	2	BIRD (PRD_000976)
3	A, B	CACODYLATE ION	non-polymer		137.0	8	Chemie (CAC)
4		water	water		18.0	763	Chemie (HOH)

Sequence modifications

A, B: 24 - 293 (UniProt: P55212)

PDB	External Database	Details
Leu 294	-	expression tag
Glu 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	65078.4
Non-Polymers*	Number of molecules	8
	Total formula weight	1095.9
All*	Total formula weight	66174.3

*Water molecules are not included.