3OD5
Crystal structure of active caspase-6 bound with Ac-VEID-CHO
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Caspase-6 | polymer | 278 | 32054.6 | 2 | UniProt (P55212) Pfam (PF00656) | Homo sapiens (human) | CASP-6, Apoptotic protease Mch-2, Caspase-6 subunit p18, Caspase-6 subunit p11 |
| 2 | B, D (C, D) | peptide aldehyde inhibitor AC-VEID-CHO | polymer | 5 | 484.5 | 2 | BIRD (PRD_000976) | ||
| 3 | E, F, G, H, I... (A, B) | CACODYLATE ION | non-polymer | 137.0 | 8 | Chemie (CAC) | |||
| 4 | M, N, O, P (A, C, B, D) | water | water | 18.0 | 763 | Chemie (HOH) |
Sequence modifications
A, B: 24 - 293 (UniProt: P55212)
| PDB | External Database | Details |
|---|---|---|
| Leu 294 | - | expression tag |
| Glu 295 | - | expression tag |
| His 296 | - | expression tag |
| His 297 | - | expression tag |
| His 298 | - | expression tag |
| His 299 | - | expression tag |
| His 300 | - | expression tag |
| His 301 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 65078.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1095.9 | |
| All* | Total formula weight | 66174.3 |
