1CQ0
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![BU of 1cq0 by Molmil](/molmil-images/mine/1cq0) | SOLUTION STRUCTURE OF A HUMAN HYPOCRETIN-2/OREXIN-B'SOLUTION STRUCTURE OF A HUMAN HYPOCRETIN-2/OREXIN-B ' | Descriptor: | PROTEIN (NEW HYPOTHALAMIC NEUROPEPTIDE/OREXIN-B28) | Authors: | Lee, K.-H, Bang, E.J, Chae, K.-J, Lee, D.W, Lee, W. | Deposit date: | 1999-08-04 | Release date: | 2000-01-10 | Last modified: | 2024-04-10 | Method: | SOLUTION NMR | Cite: | Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B. Eur.J.Biochem., 266, 1999
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8HU2
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![BU of 8hu2 by Molmil](/molmil-images/mine/8hu2) | Rattus Syntenin-1 PDZ domain with inhibitor | Descriptor: | (2~{S})-2-(9~{H}-fluoren-9-ylmethoxycarbonylamino)-3-(4-oxidanylidene-5~{H}-pyrimidin-2-yl)propanoic acid, Syntenin-1 | Authors: | Heo, Y, Lee, J, Yun, J.H, Lee, W. | Deposit date: | 2022-12-22 | Release date: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of STNPDZ with inhibitor at 1.60 Angstroms resolution. To Be Published
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1RJA
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7LHQ
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![BU of 7lhq by Molmil](/molmil-images/mine/7lhq) | Solution structure of SARS-CoV-2 nonstructural protein 7 at pH 7.0 | Descriptor: | Non-structural protein 7 | Authors: | Lee, Y, Tonelli, M, Anderson, T.K, Kirchdoerfer, R.N, Henzler-Wildman, K, Lee, W. | Deposit date: | 2021-01-26 | Release date: | 2022-02-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | pH-dependent polymorphism of the structure of SARS-CoV-2 nsp7 Biorxiv, 2021
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1RYJ
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![BU of 1ryj by Molmil](/molmil-images/mine/1ryj) | Solution NMR Structure of Protein Mth1743 from Methanobacterium thermoautotrophicum. Ontario Centre for Structural Proteomics target MTH1743_1_70; Northeast Structural Genomics Consortium Target TT526. | Descriptor: | unknown | Authors: | Yee, A, Chang, X, Pineda-Lucena, A, Wu, B, Semesi, A, Le, B, Ramelot, T, Lee, G.M, Bhattacharyya, S, Gutierrez, P, Denisov, A, Lee, C.H, Cort, J.R, Kozlov, G, Liao, J, Finak, G, Chen, L, Wishart, D, Lee, W, McIntosh, L.P, Gehring, K, Kennedy, M.A, Edwards, A.M, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-12-22 | Release date: | 2004-02-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | AN NMR APPROACH TO STRUCTURAL PROTEOMICS Proc.Natl.Acad.Sci.USA, 99, 2002
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6OCV
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1EJQ
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![BU of 1ejq by Molmil](/molmil-images/mine/1ejq) | SOLUTION STRUCTURE OF THE SYNDECAN-4 WHOLE CYTOPLASMIC DOMAIN IN THE PRESENCE OF PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE | Descriptor: | SYNDECAN-4 | Authors: | Shin, J, Oh, E.S, Lee, D, Couchman, J.R, Lee, W. | Deposit date: | 2000-03-04 | Release date: | 2001-03-07 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | SOLUTION STRUCTURE OF THE SYNDECAN-4 WHOLE CYTOPLASMIC DOMAIN IN THE PRESENCE OF PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE To be Published
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1EJP
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![BU of 1ejp by Molmil](/molmil-images/mine/1ejp) | SOLUTION STRUCTURE OF THE SYNDECAN-4 WHOLE CYTOPLASMIC DOMAIN | Descriptor: | SYNDECAN-4 | Authors: | Lee, D, Oh, E.S, Woods, A, Couchman, J.R, Lee, W. | Deposit date: | 2000-03-03 | Release date: | 2001-09-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the dimeric cytoplasmic domain of syndecan-4. Biochemistry, 40, 2001
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2HQR
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![BU of 2hqr by Molmil](/molmil-images/mine/2hqr) | |
2HQO
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2HQN
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8Y4Z
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![BU of 8y4z by Molmil](/molmil-images/mine/8y4z) | Monomeric HERC5 HECT c-lobe structure in solution | Descriptor: | E3 ISG15--protein ligase HERC5 | Authors: | Dag, C, Lambert, M, Kahraman, K, Lohn, F, Lee, W, Gocenler, O, Guntert, P, Dotsch, V. | Deposit date: | 2024-01-31 | Release date: | 2024-02-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Monomeric HERC5 HECT c-lobe structure in solution To Be Published
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8WWX
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6T8W
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![BU of 6t8w by Molmil](/molmil-images/mine/6t8w) | Complement factor B in complex with (-)-4-(1-((5,7-Dimethyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic acid | Descriptor: | 5,7-dimethyl-4-[[(2~{S})-2-phenylpiperidin-1-yl]methyl]-1~{H}-indole, Complement factor B, SULFATE ION, ... | Authors: | Mainolfi, N, Ehara, T, Karki, R.G, Anderson, K, Sweeney, A.M, Wiesmann, C, Adams, C, Mainolfi, N, Liao, S.M, Argikar, U.A, Jendza, K, Zhang, C, Powers, J, Klosowski, D.W, Crowley, M, Kawanami, T, Ding, J, April, M, Forster, C, Wu, M.S, Capparelli, M, Ramqaj, R, Solovay, C, Cumin, F, Smith, T.M, Ferrara, L, Lee, W, Long, D, Prentiss, M, Erkenez, A.D, Yang, L, Fang, L, Sellner, H, Sirockin, F, Valeur, E, Erbel, P, Ramage, P, Gerhartz, B, Schubart, A, Flohr, S, Gradoux, N, Feifel, R, Vogg, B, Wiesmann, C, Maibaum, J, Eder, J, Sedrani, R, Harrison, R.A, Mogi, M, Jaffee, B.D, Adams, C.M. | Deposit date: | 2019-10-25 | Release date: | 2020-03-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases. J.Med.Chem., 63, 2020
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6T8U
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![BU of 6t8u by Molmil](/molmil-images/mine/6t8u) | Complement factor B in complex with 5-Bromo-3-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-7-methyl-1H-indol-4-amine | Descriptor: | 5-bromanyl-3-chloranyl-~{N}-(1~{H}-imidazol-2-yl)-7-methyl-1~{H}-indol-4-amine, Complement factor B, SULFATE ION | Authors: | Mainolfi, N, Ehara, T, Karki, R.G, Anderson, K, Mac Sweeney, A, Wiesmann, C, Adams, C, Liao, S.-M, Argikar, U.A, Jendza, K, Zhang, C, Powers, J, Klosowski, D.W, Crowley, M, Kawanami, T, Ding, J, April, M, Forster, C, Serrano-Wu, M, Capparelli, M, Ramqaj, R, Solovay, C, Cumin, F, Smith, T.M, Ferrara, L, Lee, W, Long, D, Prentiss, M, De Erkenez, A, Yang, L, Fang, L, Sellner, H, Sirockin, F, Valeur, E, Erbel, P, Ramage, P, Gerhartz, B, Schubart, A, Flohr, S, Gradoux, N, Feifel, R, Vogg, B, Maibaum, J, Eder, J, Sedrani, R, Harrison, R.A, Mogi, M, Jaffee, B.D, Adams, C.M. | Deposit date: | 2019-10-25 | Release date: | 2020-03-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases. J.Med.Chem., 63, 2020
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5ZTK
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![BU of 5ztk by Molmil](/molmil-images/mine/5ztk) | Synchrotron structure of light-driven chloride pump having an NTQ motif | Descriptor: | CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ... | Authors: | Yun, J.H, Park, J.H, Park, S.Y, Lee, W. | Deposit date: | 2018-05-04 | Release date: | 2018-12-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency J. Biol. Chem., 294, 2019
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4ZG0
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![BU of 4zg0 by Molmil](/molmil-images/mine/4zg0) | Crystal structure of Mouse Syndesmos protein | Descriptor: | Protein syndesmos | Authors: | Lee, I, Kim, H, Yoo, J, Cho, H, Lee, W. | Deposit date: | 2015-04-22 | Release date: | 2016-04-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.006 Å) | Cite: | Crystal structure of syndesmos and its interaction with Syndecan-4 proteoglycan Biochem.Biophys.Res.Commun., 463, 2015
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5VSO
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![BU of 5vso by Molmil](/molmil-images/mine/5vso) | NMR structure of Ydj1 J-domain, a cytosolic Hsp40 from Saccharomyces cerevisiae | Descriptor: | Yeast dnaJ protein 1 | Authors: | Ciesielski, S.J, Tonelli, M, Lee, W, Cornilescu, G, Markley, J.L, Schilke, B.A, Ziegelhoffer, T, Craig, E.A. | Deposit date: | 2017-05-12 | Release date: | 2017-11-01 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Broadening the functionality of a J-protein/Hsp70 molecular chaperone system. PLoS Genet., 13, 2017
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6T8V
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![BU of 6t8v by Molmil](/molmil-images/mine/6t8v) | Complement factor B in complex with (S)-5,7-Dimethyl-4-((2-phenylpiperidin-1-yl)methyl)-1H-indole | Descriptor: | 4-[(2~{S})-1-[(5,7-dimethyl-1~{H}-indol-4-yl)methyl]piperidin-2-yl]benzoic acid, Complement factor B, SULFATE ION, ... | Authors: | Mainolfi, N, Ehara, T, Karki, R.G, Anderson, K, Mac Sweeney, A, Wiesmann, C, Adams, C, Mainolfi, N, Liao, S.-M, Argikar, U.A, Jendza, K, Zhang, C, Powers, J, Klosowski, D.W, Crowley, M, Kawanami, T, Ding, J, April, M, Forster, C, Serrano-Wu, M, Capparelli, M, Ramqaj, R, Solovay, C, Cumin, F, Smith, T.M, Ferrara, L, Lee, W, Long, D, Prentiss, M, De Erkenez, A, Yang, L, Fang, L, Sellner, H, Sirockin, F, Valeur, E, Erbel, P, Ramage, P, Gerhartz, B, Schubart, A, Flohr, S, Gradoux, N, Feifel, R, Vogg, B, Wiesmann, C, Maibaum, J, Eder, J, Sedrani, R, Harrison, R.A, Mogi, M, Jaffee, B.D, Adams, C.M. | Deposit date: | 2019-10-25 | Release date: | 2020-03-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases. J.Med.Chem., 63, 2020
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5G1D
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![BU of 5g1d by Molmil](/molmil-images/mine/5g1d) | The complex structure of syntenin-1 PDZ domain with c-terminal extension | Descriptor: | SYNDECAN-4, SYNTENIN-1 | Authors: | Lee, I, Kim, H, Yun, J.H, Lee, W. | Deposit date: | 2016-03-25 | Release date: | 2016-11-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | New Structural Insight of C-Terminal Region of Syntenin-1, Enhancing the Molecular Dimerization and Inhibitory Function Related on Syndecan-4 Signaling. Sci.Rep., 6, 2016
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5G1E
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![BU of 5g1e by Molmil](/molmil-images/mine/5g1e) | The complex structure of syntenin-1 PDZ domain with c-terminal extension | Descriptor: | SYNTENIN-1 | Authors: | Lee, I, Kim, H, Yun, J.H, Lee, W. | Deposit date: | 2016-03-25 | Release date: | 2016-11-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | New Structural Insight of C-Terminal Region of Syntenin-1, Enhancing the Molecular Dimerization and Inhibitory Function Related on Syndecan-4 Signaling. Sci.Rep., 6, 2016
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5ZTL
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![BU of 5ztl by Molmil](/molmil-images/mine/5ztl) | Non-cryogenic structure of light-driven chloride pump having an NTQ motif | Descriptor: | CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ... | Authors: | Yun, J.H, Park, S.Y, Liu, H, Lee, W. | Deposit date: | 2018-05-04 | Release date: | 2018-12-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency J. Biol. Chem., 294, 2019
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1IQS
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![BU of 1iqs by Molmil](/molmil-images/mine/1iqs) | Minimized average structure of MTH1880 from Methanobacterium Thermoautotrophicum | Descriptor: | MTH1880 | Authors: | Lee, C.H, Shin, J, Bang, E, Jung, J.W, Yee, A, Arrowsmith, C.H, Lee, W. | Deposit date: | 2001-07-29 | Release date: | 2002-07-29 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of a novel calcium binding protein, MTH1880, from Methanobacterium thermoautotrophicum. Protein Sci., 13, 2004
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1IQO
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![BU of 1iqo by Molmil](/molmil-images/mine/1iqo) | Solution structure of MTH1880 from methanobacterium thermoautotrophicum | Descriptor: | HYPOTHETICAL PROTEIN MTH1880 | Authors: | Lee, C.H, Shin, J, Bang, E, Jung, J.W, Yee, A, Arrowsmith, C.H, Lee, W. | Deposit date: | 2001-07-23 | Release date: | 2002-07-24 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of a novel calcium binding protein, MTH1880, from Methanobacterium thermoautotrophicum. Protein Sci., 13, 2004
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2KCC
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![BU of 2kcc by Molmil](/molmil-images/mine/2kcc) | Solution Structure of biotinoyl domain from human acetyl-CoA carboxylase 2 | Descriptor: | Acetyl-CoA carboxylase 2 | Authors: | Lee, C, Cheong, H, Ryu, K, Lee, J, Lee, W, Jeon, Y, Cheong, C. | Deposit date: | 2008-12-19 | Release date: | 2009-02-17 | Last modified: | 2023-09-27 | Method: | SOLUTION NMR | Cite: | Biotinoyl domain of human acetyl-CoA carboxylase: Structural insights into the carboxyl transfer mechanism. Proteins, 72, 2008
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