4B5Q
 
 | | The lytic polysaccharide monooxygenase GH61D structure from the basidiomycota fungus Phanerochaete chrysosporium | | Descriptor: | COPPER (II) ION, GLYCEROL, GLYCOSIDE HYDROLASE FAMILY 61 PROTEIN D, ... | | Authors: | Wu, M, Beckham, G.T, Larsson, A.M, Ishida, T, Kim, S, Crowley, M.F, Payne, C.M, Horn, S.J, Westereng, B, Stahlberg, J, Eijsink, V.G.H, Sandgren, M. | | Deposit date: | 2012-08-07 | | Release date: | 2013-04-03 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal Structure and Computational Characterization of the Lytic Polysaccharide Monooxygenase Gh61D from the Basidiomycota Fungus Phanerochaete Chrysosporium
J.Biol.Chem., 288, 2013
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2A1R
 | | Crystal structure of PARN nuclease domain | | Descriptor: | 5'-R(*AP*AP*A)-3', Poly(A)-specific ribonuclease PARN | | Authors: | Wu, M, Song, H. | | Deposit date: | 2005-06-21 | | Release date: | 2005-12-20 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural insight into poly(A) binding and catalytic mechanism of human PARN
Embo J., 24, 2005
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2A1S
 | | Crystal structure of native PARN nuclease domain | | Descriptor: | Poly(A)-specific ribonuclease PARN | | Authors: | Wu, M, Song, H. | | Deposit date: | 2005-06-21 | | Release date: | 2005-12-20 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural insight into poly(A) binding and catalytic mechanism of human PARN
Embo J., 24, 2005
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7T3F
 | | Development of BRD4 inhibitors as arsenicals antidotes | | Descriptor: | 4-fluoro-3-methyl-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzene-1-sulfonamide, Bromodomain-containing protein 4, GLYCEROL | | Authors: | Wu, M, Yatchang, M, Mathew, B, Zhai, L, Ruiz, P, Bostwick, R, Augelli-Szafran, C.E, Suto, M.J. | | Deposit date: | 2021-12-07 | | Release date: | 2022-08-31 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.28 Å) | | Cite: | Development of BRD4 inhibitors as anti-inflammatory agents and antidotes for arsenicals.
Bioorg.Med.Chem.Lett., 64, 2022
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4AX6
 | | HYPOCREA JECORINA CEL6A D221A MUTANT SOAKED WITH 6-CHLORO-4- PHENYLUMBELLIFERYL-BETA-CELLOBIOSIDE | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-chloranyl-7-oxidanyl-4-phenyl-chromen-2-one, EXOGLUCANASE 2, ... | | Authors: | Wu, M, Nerinckx, W, Piens, K, Ishida, T, Hansson, H, Stahlberg, J, Sandgren, M. | | Deposit date: | 2012-06-10 | | Release date: | 2013-01-23 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Rational Design, Synthesis, Evaluation and Enzyme-Substrate Structures of Improved Fluorogenic Substrates for Family 6 Glycoside Hydrolases.
FEBS J., 280, 2013
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4AX7
 | | Hypocrea jecorina Cel6A D221A mutant soaked with 4-Methylumbelliferyl- beta-D-cellobioside | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-hydroxy-4-methyl-2H-chromen-2-one, EXOGLUCANASE 2, ... | | Authors: | Wu, M, Nerinckx, W, Piens, K, Ishida, T, Hansson, H, Stahlberg, J, Sandgren, M. | | Deposit date: | 2012-06-11 | | Release date: | 2013-01-23 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Rational Design, Synthesis, Evaluation and Enzyme-Substrate Structures of Improved Fluorogenic Substrates for Family 6 Glycoside Hydrolases.
FEBS J., 280, 2013
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4AU0
 | | Hypocrea jecorina Cel6A D221A mutant soaked with 6-chloro-4- methylumbelliferyl-beta-cellobioside | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-chloro-7-hydroxy-4-methyl-2H-chromen-2-one, EXOGLUCANASE 2, ... | | Authors: | Wu, M, Nerinckx, W, Piens, K, Ishida, T, Hansson, H, Stahlberg, J, Sandgren, M. | | Deposit date: | 2012-05-11 | | Release date: | 2013-01-23 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Rational Design, Synthesis, Evaluation and Enzyme-Substrate Structures of Improved Fluorogenic Substrates for Family 6 Glycoside Hydrolases.
FEBS J., 280, 2013
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4AVO
 | | Thermobifida fusca cellobiohydrolase Cel6B catalytic mutant D274A cocrystallized with cellobiose | | Descriptor: | ACETATE ION, BETA-1,4-EXOCELLULASE, CALCIUM ION, ... | | Authors: | Wu, M, Vuong, T.V, Wilson, D.B, Sandgren, M, Stahlberg, J, Hansson, H. | | Deposit date: | 2012-05-28 | | Release date: | 2013-06-12 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Loop Motions Important to Product Expulsion in the Thermobifida Fusca Glycoside Hydrolase Family 6 Cellobiohydrolase from Structural and Computational Studies.
J.Biol.Chem., 288, 2013
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4AVN
 | | Thermobifida fusca cellobiohydrolase Cel6B catalytic mutant D226A- S232A cocrystallized with cellobiose | | Descriptor: | CALCIUM ION, CELLOBIOHYDROLASE. GLYCOSYL HYDROLASE FAMILY 6, beta-D-glucopyranose, ... | | Authors: | Wu, M, Vuong, T.V, Wilson, D.B, Sandgren, M, Stahlberg, J, Hansson, H. | | Deposit date: | 2012-05-28 | | Release date: | 2013-06-12 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Loop Motions Important to Product Expulsion in the Thermobifida Fusca Glycoside Hydrolase Family 6 Cellobiohydrolase from Structural and Computational Studies.
J.Biol.Chem., 288, 2013
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3E9T
 | | Crystal structure of Apo-form Calx CBD1 domain | | Descriptor: | CALCIUM ION, Na/Ca exchange protein | | Authors: | Wu, M, Zheng, L. | | Deposit date: | 2008-08-23 | | Release date: | 2009-09-01 | | Last modified: | 2023-07-05 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structures of progressive Ca2+ binding states of the Ca2+ sensor Ca2+ binding domain 1 (CBD1) from the CALX Na+/Ca2+ exchanger reveal incremental conformational transitions.
J.Biol.Chem., 285, 2010
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6W0T
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6VUQ
 | | Crystal structure of CHIKV nsP3 macrodomain soaked with ADP-ribose | | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Nonstructural polyprotein | | Authors: | Wu, M. | | Deposit date: | 2020-02-16 | | Release date: | 2021-01-13 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design.
Plos One, 16, 2021
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3E9U
 | | Crystal structure of Calx CBD2 domain | | Descriptor: | Na/Ca exchange protein | | Authors: | Wu, M, Zheng, L. | | Deposit date: | 2008-08-23 | | Release date: | 2009-01-27 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of CBD2 from the Drosophila Na(+)/Ca(2+) exchanger: diversity of Ca(2+) regulation and its alternative splicing modification.
J.Mol.Biol., 387, 2009
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6V20
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6V21
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1MIS
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1MWG
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1R4A
 | | Crystal Structure of GTP-bound ADP-ribosylation Factor Like Protein 1 (Arl1) and GRIP Domain of Golgin245 COMPLEX | | Descriptor: | ADP-ribosylation factor-like protein 1, Golgi autoantigen, golgin subfamily A member 4, ... | | Authors: | Wu, M, Lu, L, Hong, W, Song, H. | | Deposit date: | 2003-10-04 | | Release date: | 2004-01-13 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for recruitment of GRIP domain golgin-245 by small GTPase Arl1.
Nat.Struct.Mol.Biol., 11, 2004
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4E4H
 | | Crystal structure of Histone Demethylase NO66 | | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, FE (III) ION, ... | | Authors: | Wu, M, Tao, Y, Zang, J. | | Deposit date: | 2012-03-13 | | Release date: | 2013-01-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | tructural Basis for Tetramerization-dependent Gene Repression by Histone Demethylase NO66
To be Published
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3D45
 | | Crystal structure of mouse PARN in complex with m7GpppG | | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Poly(A)-specific ribonuclease PARN | | Authors: | Wu, M, Song, H. | | Deposit date: | 2008-05-13 | | Release date: | 2009-03-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis of m(7)GpppG binding to poly(A)-specific ribonuclease.
Structure, 17, 2009
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4KJS
 | | Structure of native YfkE | | Descriptor: | cation exchanger YfkE | | Authors: | Wu, M, Tong, S, Zheng, L. | | Deposit date: | 2013-05-03 | | Release date: | 2013-06-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Crystal structure of Ca2+/H+ antiporter protein YfkE reveals the mechanisms of Ca2+ efflux and its pH regulation.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4KJR
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7T91
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1YHN
 | | Structure basis of RILP recruitment by Rab7 | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab interacting lysosomal protein, ... | | Authors: | Wu, M, Wang, T, Hong, W, Song, H. | | Deposit date: | 2005-01-10 | | Release date: | 2005-05-17 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for recruitment of RILP by small GTPase Rab7.
Embo J., 24, 2005
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3N2Y
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