2RFJ
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![BU of 2rfj by Molmil](/molmil-images/mine/2rfj) | Crystal structure of the bromo domain 1 in human bromodomain containing protein, testis specific (BRDT) | Descriptor: | Bromodomain testis-specific protein | Authors: | Filippakopoulos, P, Salah, E, Savitsky, P, Keates, T, Parizotto, E, Elkins, J, Pike, A.C.W, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Sundstrom, M, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2007-09-30 | Release date: | 2007-10-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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3CD3
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![BU of 3cd3 by Molmil](/molmil-images/mine/3cd3) | Crystal structure of phosphorylated human feline sarcoma viral oncogene homologue (v-FES) in complex with staurosporine and a consensus peptide | Descriptor: | CHLORIDE ION, Proto-oncogene tyrosine-protein kinase Fes/Fps, STAUROSPORINE, ... | Authors: | Filippakopoulos, P, Salah, E, Cooper, C, Picaud, S.S, Elkins, J.M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-02-26 | Release date: | 2008-03-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation Cell(Cambridge,Mass.), 134, 2008
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3CBL
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![BU of 3cbl by Molmil](/molmil-images/mine/3cbl) | Crystal structure of human feline sarcoma viral oncogene homologue (v-FES) in complex with staurosporine and a consensus peptide | Descriptor: | Proto-oncogene tyrosine-protein kinase Fes/Fps, STAUROSPORINE, Synthetic peptide | Authors: | Filippakopoulos, P, Salah, E, Cooper, C, Picaud, S.S, Elkins, J.M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-02-22 | Release date: | 2008-03-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation Cell(Cambridge,Mass.), 134, 2008
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3TWR
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![BU of 3twr by Molmil](/molmil-images/mine/3twr) | Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human 3BP2 | Descriptor: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, SH3 domain-binding protein 2, SULFATE ION, ... | Authors: | Guettler, S, Sicheri, F. | Deposit date: | 2011-09-22 | Release date: | 2011-12-07 | Last modified: | 2011-12-28 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease. Cell(Cambridge,Mass.), 147, 2011
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3TWX
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![BU of 3twx by Molmil](/molmil-images/mine/3twx) | Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human FNBP1 (chimeric peptide) | Descriptor: | 1,2-ETHANEDIOL, HEXAETHYLENE GLYCOL, SULFATE ION, ... | Authors: | Guettler, S, Sicheri, F. | Deposit date: | 2011-09-22 | Release date: | 2011-12-07 | Last modified: | 2011-12-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease. Cell(Cambridge,Mass.), 147, 2011
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3TWT
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![BU of 3twt by Molmil](/molmil-images/mine/3twt) | Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human MCL1 (chimeric peptide) | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, NONAETHYLENE GLYCOL, ... | Authors: | Guettler, S, Sicheri, F. | Deposit date: | 2011-09-22 | Release date: | 2011-12-07 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease. Cell(Cambridge,Mass.), 147, 2011
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3TWU
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![BU of 3twu by Molmil](/molmil-images/mine/3twu) | |
5OAK
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![BU of 5oak by Molmil](/molmil-images/mine/5oak) | |
3DAI
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![BU of 3dai by Molmil](/molmil-images/mine/3dai) | Crystal structure of the bromodomain of the human ATAD2 | Descriptor: | ATPase family AAA domain-containing protein 2, CHLORIDE ION, SULFATE ION | Authors: | Filippakopoulos, P, Keates, T, Picaud, S, Fedorov, O, Roos, A.K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-05-29 | Release date: | 2008-09-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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1OW5
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![BU of 1ow5 by Molmil](/molmil-images/mine/1ow5) | |
3D7C
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![BU of 3d7c by Molmil](/molmil-images/mine/3d7c) | Crystal structure of the bromodomain of human GCN5, the general control of amino-acid synthesis protein 5-like 2 | Descriptor: | General control of amino acid synthesis protein 5-like 2 | Authors: | Filippakopoulos, P, Eswaran, J, Picaud, S, Fedorov, O, Murray, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-05-21 | Release date: | 2008-07-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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3DWY
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![BU of 3dwy by Molmil](/molmil-images/mine/3dwy) | Crystal Structure of the Bromodomain of Human CREBBP | Descriptor: | 1,2-ETHANEDIOL, CREB-binding protein | Authors: | Filippakopoulos, P, Picaud, S, Fedorov, O, Karim, R, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Wickstroem, M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-07-23 | Release date: | 2008-08-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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1MIL
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![BU of 1mil by Molmil](/molmil-images/mine/1mil) | TRANSFORMING PROTEIN | Descriptor: | SHC ADAPTOR PROTEIN | Authors: | Mikol, V. | Deposit date: | 1995-09-20 | Release date: | 1996-11-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the SH2 domain from the adaptor protein SHC: a model for peptide binding based on X-ray and NMR data. J.Mol.Biol., 254, 1995
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3Q2E
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![BU of 3q2e by Molmil](/molmil-images/mine/3q2e) | Crystal structure of the second bromodomain of human bromodomain and WD repeat-containing protein 1 isoform A (WDR9) | Descriptor: | ACETATE ION, Bromodomain and WD repeat-containing protein 1 | Authors: | Filippakopoulos, P, Felletar, I, Picaud, S, Keates, T, Krojer, T, Muniz, J, Gileadi, O, Von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-12-20 | Release date: | 2011-02-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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3RCW
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![BU of 3rcw by Molmil](/molmil-images/mine/3rcw) | Crystal Structure of the bromodomain of human BRD1 | Descriptor: | 1,2-ETHANEDIOL, 1-methylpyrrolidin-2-one, ACETATE ION, ... | Authors: | Filippakopoulos, P, Keates, T, Picaud, S, Felletar, I, Pike, A.C.W, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2011-03-31 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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4GBQ
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![BU of 4gbq by Molmil](/molmil-images/mine/4gbq) | SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, 15 STRUCTURES | Descriptor: | GRB2, SOS-1 | Authors: | Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L. | Deposit date: | 1996-12-23 | Release date: | 1997-09-04 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts. J.Mol.Biol., 267, 1997
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3BKB
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![BU of 3bkb by Molmil](/molmil-images/mine/3bkb) | Crystal structure of human Feline Sarcoma Viral Oncogene Homologue (v-FES) | Descriptor: | 1,2-ETHANEDIOL, Proto-oncogene tyrosine-protein kinase Fes/Fps, STAUROSPORINE, ... | Authors: | Filippakopoulos, P, Salah, E, Fedorov, O, Cooper, C, Ugochukwu, E, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2007-12-06 | Release date: | 2007-12-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation Cell(Cambridge,Mass.), 134, 2008
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3LXJ
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![BU of 3lxj by Molmil](/molmil-images/mine/3lxj) | Crystal Structure of the Bromodomain of Human AAA domain containing 2B (ATAD2B) | Descriptor: | ATPase family AAA domain-containing protein 2B, ISOPROPYL ALCOHOL | Authors: | Filippakopoulos, P, Keates, T, Picaud, S, Fedorov, O, Krojer, T, Vollmar, M, Muniz, J, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-02-25 | Release date: | 2010-03-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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3MQM
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![BU of 3mqm by Molmil](/molmil-images/mine/3mqm) | Crystal Structure of the Bromodomain of human ASH1L | Descriptor: | Probable histone-lysine N-methyltransferase ASH1L | Authors: | Filippakopoulos, P, Picaud, S, Keates, T, Felletar, I, Vollmar, M, Chaikuad, A, Krojer, T, Canning, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-04-28 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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3GG3
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![BU of 3gg3 by Molmil](/molmil-images/mine/3gg3) | Crystal Structure of the Bromodomain of Human PCAF | Descriptor: | CHLORIDE ION, Histone acetyltransferase PCAF | Authors: | Filippakopoulos, P, Keates, T, Picaud, S, Rehana, K, Fedorov, O, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-02-27 | Release date: | 2009-03-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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4JMG
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![BU of 4jmg by Molmil](/molmil-images/mine/4jmg) | |
4LG6
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![BU of 4lg6 by Molmil](/molmil-images/mine/4lg6) | Crystal structure of ANKRA2-CCDC8 complex | Descriptor: | Ankyrin repeat family A protein 2, Coiled-coil domain-containing protein 8, UNKNOWN ATOM OR ION | Authors: | Xu, C, Bian, C, Tempel, W, Mackenzie, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2013-06-27 | Release date: | 2013-09-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Ankyrin Repeats of ANKRA2 Recognize a PxLPxL Motif on the 3M Syndrome Protein CCDC8. Structure, 23, 2015
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3IU6
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![BU of 3iu6 by Molmil](/molmil-images/mine/3iu6) | Crystal structure of the sixth bromodomain of human poly-bromodomain containing protein 1 (PB1) | Descriptor: | 1,2-ETHANEDIOL, Protein polybromo-1, ZINC ION | Authors: | Filippakopoulos, P, Keates, T, Picaud, S, Pike, A.C.W, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-08-30 | Release date: | 2009-09-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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3IU5
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![BU of 3iu5 by Molmil](/molmil-images/mine/3iu5) | Crystal structure of the first bromodomain of human poly-bromodomain containing protein 1 (PB1) | Descriptor: | Protein polybromo-1 | Authors: | Filippakopoulos, P, Picaud, S, Keates, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-08-30 | Release date: | 2009-09-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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4JMH
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![BU of 4jmh by Molmil](/molmil-images/mine/4jmh) | |