3RCW

Crystal Structure of the bromodomain of human BRD1

Summary for 3RCW

Entry DOI	10.2210/pdb3rcw/pdb
Descriptor	Bromodomain-containing protein 1, 1-methylpyrrolidin-2-one, ACETATE ION, ... (5 entities in total)
Functional Keywords	transcription, bromodomain, structural genomics, structural genomics consortium, sgc
Biological source	Homo sapiens (human)
Cellular location	Nucleus : O95696
Total number of polymer chains	8
Total formula weight	125644.91
Authors	Filippakopoulos, P.,Keates, T.,Picaud, S.,Felletar, I.,Pike, A.C.W.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2011-03-31, release date: 2011-06-01, Last modification date: 2023-09-13)
Primary citation	Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331 DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.21 Å)

Structure validation