3RCW
Crystal Structure of the bromodomain of human BRD1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Bromodomain-containing protein 1 | polymer | 135 | 15662.9 | 8 | UniProt (O95696) Pfam (PF00439) | Homo sapiens (human) | BR140-like protein, Bromodomain and PHD finger-containing protein 2 |
| 2 | I (C) | 1-methylpyrrolidin-2-one | non-polymer | 99.1 | 1 | Chemie (MB3) | |||
| 3 | J, M (D, H) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 4 | K, L (F, G) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | N, O, P, Q, R... (A, B, C, D, E...) | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 556 - 688 (UniProt: O95696)
| PDB | External Database | Details |
|---|---|---|
| Ser 554 | - | expression tag |
| Met 555 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 125303.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 341.4 | |
| All* | Total formula weight | 125644.9 |
