3D7C
Crystal structure of the bromodomain of human GCN5, the general control of amino-acid synthesis protein 5-like 2
Summary for 3D7C
Entry DOI | 10.2210/pdb3d7c/pdb |
Descriptor | General control of amino acid synthesis protein 5-like 2 (2 entities in total) |
Functional Keywords | gcn5, bromodomain, amino-acid synthesis, structural genomics consortium, sgc, host-virus interaction, nucleus, phosphoprotein, transcription, transcription regulation, transferase, biosynthetic protein |
Biological source | Homo sapiens |
Cellular location | Nucleus: Q92830 |
Total number of polymer chains | 2 |
Total formula weight | 26574.63 |
Authors | Filippakopoulos, P.,Eswaran, J.,Picaud, S.,Fedorov, O.,Murray, J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2008-05-21, release date: 2008-07-15, Last modification date: 2023-08-30) |
Primary citation | Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.06 Å) |
Structure validation
Download full validation report