3MQM
Crystal Structure of the Bromodomain of human ASH1L
Summary for 3MQM
| Entry DOI | 10.2210/pdb3mqm/pdb |
| Descriptor | Probable histone-lysine N-methyltransferase ASH1L (2 entities in total) |
| Functional Keywords | ash1l, ash1, kiaa1420, absent small and homeotic disks protein 1 homolog, lysine n-methyltransferase 2h, kmt2h, structural genomics consortium, sgc, transferase |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus: Q9NR48 |
| Total number of polymer chains | 2 |
| Total formula weight | 28750.94 |
| Authors | Filippakopoulos, P.,Picaud, S.,Keates, T.,Felletar, I.,Vollmar, M.,Chaikuad, A.,Krojer, T.,Canning, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2010-04-28, release date: 2010-05-19, Last modification date: 2023-09-06) |
| Primary citation | Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.54 Å) |
Structure validation
Download full validation report
