3IJK
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![BU of 3ijk by Molmil](/molmil-images/mine/3ijk) | 5-OMe modified DNA 8mer | Descriptor: | 5'-D(*GP*(UMS)P*GP*(T5O)P*AP*CP*AP*C)-3' | Authors: | Sheng, J, Zhang, W, Hassan, A.E.A, Gan, J, Huang, Z. | Deposit date: | 2009-08-04 | Release date: | 2009-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate Chemistryselect, 8, 2023
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3LTU
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![BU of 3ltu by Molmil](/molmil-images/mine/3ltu) | 5-SeMe-dU containing DNA 8mer | Descriptor: | 5'-D(*GP*(UMS)P*GP*(T5S)P*AP*CP*AP*C)-3' | Authors: | Sheng, J, Hassan, A.E.A, Zhang, W, Gan, J, Huang, Z. | Deposit date: | 2010-02-16 | Release date: | 2010-03-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate Chemistryselect, 8, 2023
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5VRE
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![BU of 5vre by Molmil](/molmil-images/mine/5vre) | |
6XJV
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![BU of 6xjv by Molmil](/molmil-images/mine/6xjv) | MCU holocomplex in High-calcium state | Descriptor: | Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ... | Authors: | Wang, Y, Jiang, Y. | Deposit date: | 2020-06-24 | Release date: | 2020-09-09 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.17 Å) | Cite: | Structural insights into the Ca 2+ -dependent gating of the human mitochondrial calcium uniporter. Elife, 9, 2020
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8GRA
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![BU of 8gra by Molmil](/molmil-images/mine/8gra) | |
6XJX
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![BU of 6xjx by Molmil](/molmil-images/mine/6xjx) | MCU holocomplex in Low-calcium blocking state | Descriptor: | Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ... | Authors: | Wang, Y, Jiang, Y. | Deposit date: | 2020-06-24 | Release date: | 2020-09-09 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural insights into the Ca 2+ -dependent gating of the human mitochondrial calcium uniporter. Elife, 9, 2020
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6O58
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![BU of 6o58 by Molmil](/molmil-images/mine/6o58) | Human MCU-EMRE complex, dimer of channel | Descriptor: | CALCIUM ION, Calcium uniporter protein, mitochondrial, ... | Authors: | Wang, Y, Bai, X, Jiang, Y. | Deposit date: | 2019-03-01 | Release date: | 2019-05-22 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter. Cell, 177, 2019
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6O5B
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![BU of 6o5b by Molmil](/molmil-images/mine/6o5b) | Monomer of a cation channel | Descriptor: | CALCIUM ION, Calcium uniporter protein, mitochondrial, ... | Authors: | Wang, Y, Bai, X, Jiang, Y. | Deposit date: | 2019-03-01 | Release date: | 2019-05-22 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter. Cell, 177, 2019
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7YW0
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![BU of 7yw0 by Molmil](/molmil-images/mine/7yw0) | Bacteroides fragilis Hcp5 | Descriptor: | Bacterodales T6SS protein TssD (Hcp) | Authors: | Wen, Y, He, W, Bai, Y. | Deposit date: | 2022-08-20 | Release date: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure and assembly of type VI secretion system cargo delivery vehicle. Cell Rep, 42, 2023
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6O84
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![BU of 6o84 by Molmil](/molmil-images/mine/6o84) | Cryo-EM structure of OTOP3 from xenopus tropicalis | Descriptor: | LOC100127796 protein,LOC100127796 protein,OTOP3,LOC100127796 protein,LOC100127796 protein | Authors: | Chen, Q.F, Bai, X.C, Jiang, Y.X. | Deposit date: | 2019-03-08 | Release date: | 2019-04-24 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Structural and functional characterization of an otopetrin family proton channel. Elife, 8, 2019
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7XA9
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![BU of 7xa9 by Molmil](/molmil-images/mine/7xa9) | Structure of Arabidopsis thaliana CLCa | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chloride channel protein CLC-a, MAGNESIUM ION, ... | Authors: | Ji, S, Jin, H, Kaiming, Z, Mingxing, W, Shanshan, L, Long, C. | Deposit date: | 2022-03-17 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Cryo-EM structure of the plant nitrate transporter AtCLCa reveals characteristics of the anion-binding site and the ATP-binding pocket. J.Biol.Chem., 299, 2023
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7CCH
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![BU of 7cch by Molmil](/molmil-images/mine/7cch) | Acinetobacter baumannii histidine kinase AdeS | Descriptor: | AdeS | Authors: | Wen, Y, Felix, J. | Deposit date: | 2020-06-17 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.848 Å) | Cite: | Proteolysis and multimerization regulate signaling along the two-component regulatory system AdeRS. Iscience, 24, 2021
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7CCI
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![BU of 7cci by Molmil](/molmil-images/mine/7cci) | |
5VFD
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![BU of 5vfd by Molmil](/molmil-images/mine/5vfd) | Diazabicyclooctenone ETX2514 bound to Class D beta lactamase OXA-24 from A. baumannii | Descriptor: | (2S,5R)-1-formyl-4-methyl-5-[(sulfooxy)amino]-1,2,5,6-tetrahydropyridine-2-carboxamide, (2S,5R)-4-methyl-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]oct-3-ene-2-carboxamide, Beta-lactamase, ... | Authors: | Olivier, N.B, Lahiri, S. | Deposit date: | 2017-04-07 | Release date: | 2017-06-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | ETX2514 is a broad-spectrum beta-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii. Nat Microbiol, 2, 2017
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1MOZ
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![BU of 1moz by Molmil](/molmil-images/mine/1moz) | ADP-ribosylation factor-like 1 (ARL1) from Saccharomyces cerevisiae | Descriptor: | ADP-ribosylation factor-like protein 1, GUANOSINE-5'-DIPHOSPHATE | Authors: | Amor, J.C, Horton, J.R, Zhu, X, Wang, Y, Sullards, C, Ringe, D, Cheng, X, Kahn, R.A. | Deposit date: | 2002-09-10 | Release date: | 2002-10-09 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (3.17 Å) | Cite: | Structures of Yeast ARF2 and ARL1:
DISTINCT ROLES FOR THE N TERMINUS IN THE STRUCTURE
AND FUNCTION OF ARF FAMILY GTPases J.Biol.Chem., 276, 2001
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3H42
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![BU of 3h42 by Molmil](/molmil-images/mine/3h42) | Crystal structure of PCSK9 in complex with Fab from LDLR competitive antibody | Descriptor: | Fab from LDLR competitive antibody: Heavy chain, Fab from LDLR competitive antibody: Light chain, Proprotein convertase subtilisin/kexin type 9, ... | Authors: | Piper, D.E, Walker, N.P.C, Romanow, W.G, Thibault, S.T, Tsai, M.M, Yang, E. | Deposit date: | 2009-04-17 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | From the Cover: A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. Proc.Natl.Acad.Sci.USA, 106, 2009
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1ML7
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![BU of 1ml7 by Molmil](/molmil-images/mine/1ml7) | Crystal structure of nitrophorin 4 complexed with 4-iodopyrazole | Descriptor: | 4-IODOPYRAZOLE, 5,8-DIMETHYL-1,2,3,4-TETRAVINYLPORPHINE-6,7-DIPROPIONIC ACID FERROUS COMPLEX, nitrophorin 4 | Authors: | Berry, R.E, Ding, X.D, Weichsel, A, Montfort, W.R, Walker, F.A. | Deposit date: | 2002-08-30 | Release date: | 2002-09-20 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Axial ligand complexes of the Rhodnius nitrophorins: reduction potentials, binding constants, EPR spectra, and structures of the 4-iodopyrazole and imidazole complexes of NP4 J.Biol.Inorg.Chem., 9, 2004
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7XD2
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![BU of 7xd2 by Molmil](/molmil-images/mine/7xd2) | |
3HHU
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![BU of 3hhu by Molmil](/molmil-images/mine/3hhu) | Human heat-shock protein 90 (HSP90) in complex with {4-[3-(2,4-dihydroxy-5-isopropyl-phenyl)-5-thioxo- 1,5-dihydro-[1,2,4]triazol-4-yl]-benzyl}-carbamic acid ethyl ester {ZK 2819} | Descriptor: | Heat shock protein HSP 90-alpha, ethyl (4-{3-[2,4-dihydroxy-5-(1-methylethyl)phenyl]-5-sulfanyl-4H-1,2,4-triazol-4-yl}benzyl)carbamate | Authors: | Adler, M, Whitlow, M. | Deposit date: | 2009-05-17 | Release date: | 2009-07-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Potent triazolothione inhibitor of heat-shock protein-90. Chem.Biol.Drug Des., 74, 2009
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9EOU
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![BU of 9eou by Molmil](/molmil-images/mine/9eou) | |
6KDT
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![BU of 6kdt by Molmil](/molmil-images/mine/6kdt) | Crystal structure of human DNMT3B (Q772R)-DNMT3L complex | Descriptor: | DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, FORMIC ACID, ... | Authors: | Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. | Deposit date: | 2019-07-02 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.87 Å) | Cite: | Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
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4OEW
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![BU of 4oew by Molmil](/molmil-images/mine/4oew) | Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors | Descriptor: | 6-ethyl-5-iodo-2-{5-[(4-methylpiperazin-1-yl)sulfonyl]-2-propoxyphenyl}pyrimidin-4(3H)-one, MAGNESIUM ION, ZINC ION, ... | Authors: | Chen, T.T, Ren, J, Xu, Y.C. | Deposit date: | 2014-01-14 | Release date: | 2015-04-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Thermodynamic and structural characterization of halogen bonding in protein-ligand interactions: a case study of PDE5 and its inhibitors. J.Med.Chem., 57, 2014
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6KDB
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![BU of 6kdb by Molmil](/molmil-images/mine/6kdb) | Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpT site | Descriptor: | DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... | Authors: | Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. | Deposit date: | 2019-07-01 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.862 Å) | Cite: | Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
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6KDA
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![BU of 6kda by Molmil](/molmil-images/mine/6kda) | Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpG site | Descriptor: | DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... | Authors: | Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. | Deposit date: | 2019-07-01 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.909 Å) | Cite: | Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
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4OKG
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![BU of 4okg by Molmil](/molmil-images/mine/4okg) | |