7N2V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2v by Molmil](/molmil-images/mine/7n2v) | Elongating 70S ribosome complex in a spectinomycin-stalled intermediate state of translocation bound to EF-G in an active, GTP conformation (INT1) | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | Deposit date: | 2021-05-29 | Release date: | 2021-07-14 | Last modified: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | Structural basis of early translocation events on the ribosome. Nature, 595, 2021
|
|
7N2C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2c by Molmil](/molmil-images/mine/7n2c) | Elongating 70S ribosome complex in a fusidic acid-stalled intermediate state of translocation bound to EF-G(GDP) (INT2) | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | Deposit date: | 2021-05-28 | Release date: | 2021-07-14 | Last modified: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (2.72 Å) | Cite: | Structural basis of early translocation events on the ribosome. Nature, 595, 2021
|
|
7N31
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n31 by Molmil](/molmil-images/mine/7n31) | Elongating 70S ribosome complex in a post-translocation (POST) conformation | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | Deposit date: | 2021-05-31 | Release date: | 2021-07-14 | Last modified: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | Structural basis of early translocation events on the ribosome. Nature, 595, 2021
|
|
5IPK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ipk by Molmil](/molmil-images/mine/5ipk) | Structure of the R432A variant of Adeno-associated virus type 2 VLP | Descriptor: | Capsid protein VP1 | Authors: | Drouin, L.M, Lins, B, Janssen, M.E, Bennet, A, Chipman, P, McKenna, R, Chen, W, Muzyczka, N, Cardone, G, Baker, T.S, Agbandje-McKenna, M. | Deposit date: | 2016-03-09 | Release date: | 2016-07-20 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Cryo-electron Microscopy Reconstruction and Stability Studies of the Wild Type and the R432A Variant of Adeno-associated Virus Type 2 Reveal that Capsid Structural Stability Is a Major Factor in Genome Packaging. J.Virol., 90, 2016
|
|
5X4T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x4t by Molmil](/molmil-images/mine/5x4t) | |
5XH9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xh9 by Molmil](/molmil-images/mine/5xh9) | Aspergillus kawachii beta-fructofuranosidase | Descriptor: | Extracellular invertase, SODIUM ION | Authors: | Nagaya, M, Tonozuka, T. | Deposit date: | 2017-04-19 | Release date: | 2017-07-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of a beta-fructofuranosidase with high transfructosylation activity from Aspergillus kawachii Biosci. Biotechnol. Biochem., 81, 2017
|
|
7NKX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nkx by Molmil](/molmil-images/mine/7nkx) | RNA polymerase II-Spt4/5-nucleosome-Chd1 structure | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin elongation factor SPT4, ... | Authors: | Farnung, L, Ochmann, M, Engeholm, M, Cramer, P. | Deposit date: | 2021-02-19 | Release date: | 2021-08-25 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of nucleosome transcription mediated by Chd1 and FACT. Nat.Struct.Mol.Biol., 28, 2021
|
|
8COL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8col by Molmil](/molmil-images/mine/8col) | Crystal structure of Rhizobium etli constitutive L-asparaginase ReAIV (orthorombic form R4oP-2) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Loch, J.I, Worsztynowicz, P, Sliwiak, J, Imioloczyk, B, Grzechowiak, M, Gilski, M, Jaskolski, M. | Deposit date: | 2023-02-28 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Rhizobium etli has two L-asparaginases with low sequence identity but similar structure and catalytic center. Acta Crystallogr D Struct Biol, 79, 2023
|
|
8CLZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8clz by Molmil](/molmil-images/mine/8clz) | Crystal structure of Rhizobium etli constitutive L-asparaginase ReAIV (monoclinic form R4mC-2) | Descriptor: | CHLORIDE ION, Putative L-asparaginase II protein, ZINC ION | Authors: | Loch, J.I, Worsztynowicz, P, Sliwiak, J, Imiolczyk, B, Grzechowiak, M, Gilski, M, Jaskolski, M. | Deposit date: | 2023-02-17 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | Rhizobium etli has two L-asparaginases with low sequence identity but similar structure and catalytic center. Acta Crystallogr D Struct Biol, 79, 2023
|
|
5XOD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xod by Molmil](/molmil-images/mine/5xod) | Crystal structure of human Smad2-Ski complex | Descriptor: | Mothers against decapentaplegic homolog 2, Ski oncogene | Authors: | Miyazono, K, Moriwaki, S, Ito, T, Tanokura, M. | Deposit date: | 2017-05-27 | Release date: | 2018-03-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.851 Å) | Cite: | Hydrophobic patches on SMAD2 and SMAD3 determine selective binding to cofactors Sci Signal, 11, 2018
|
|
8CLY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cly by Molmil](/molmil-images/mine/8cly) | Crystal structure of Rhizobium etli constitutive L-asparaginase ReAIV (tetragonal form R4tP) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Putative L-asparaginase II protein, ... | Authors: | Loch, J.I, Worsztynowicz, P, Sliwiak, J, Imiolczyk, B, Grzechowiak, M, Gilski, M, Jaskolski, M. | Deposit date: | 2023-02-17 | Release date: | 2023-08-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.503 Å) | Cite: | Rhizobium etli has two L-asparaginases with low sequence identity but similar structure and catalytic center. Acta Crystallogr D Struct Biol, 79, 2023
|
|
5X4V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x4v by Molmil](/molmil-images/mine/5x4v) | Roseoflavin substituted OaPAC | Descriptor: | 1-deoxy-1-[8-(dimethylamino)-7-methyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl]-D-ribitol, Photoactivated adenylyl cyclase | Authors: | Ohki, M, Park, S.-Y. | Deposit date: | 2017-02-14 | Release date: | 2017-07-26 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular mechanism of photoactivation of a light-regulated adenylate cyclase. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5X7B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x7b by Molmil](/molmil-images/mine/5x7b) | Crystal structure of SHP2_SH2-CagA EPIYA_C peptide complex | Descriptor: | CagA, Tyrosine-protein phosphatase non-receptor type 11 | Authors: | Senda, M, Senda, T. | Deposit date: | 2017-02-24 | Release date: | 2017-09-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Differential Mechanisms for SHP2 Binding and Activation Are Exploited by Geographically Distinct Helicobacter pylori CagA Oncoproteins. Cell Rep, 20, 2017
|
|
2PCF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2pcf by Molmil](/molmil-images/mine/2pcf) | THE COMPLEX OF CYTOCHROME F AND PLASTOCYANIN DETERMINED WITH PARAMAGNETIC NMR. BASED ON THE STRUCTURES OF CYTOCHROME F AND PLASTOCYANIN, 10 STRUCTURES | Descriptor: | COPPER (II) ION, CYTOCHROME F, HEME C, ... | Authors: | Ubbink, M, Ejdeback, M, Karlsson, B.G, Bendall, D.S. | Deposit date: | 1997-12-22 | Release date: | 1998-04-08 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | The structure of the complex of plastocyanin and cytochrome f, determined by paramagnetic NMR and restrained rigid-body molecular dynamics. Structure, 6, 1998
|
|
6LPK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lpk by Molmil](/molmil-images/mine/6lpk) | A2AR crystallized in EROCOC17+4, LCP-SFX at 293 K | Descriptor: | 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, CHOLESTEROL, ... | Authors: | Ihara, K, Hato, M, Nakane, T, Yamashita, K, Kimura-Someya, T, Hosaka, T, Ishizuka-Katsura, Y, Tanaka, R, Tanaka, T, Sugahara, M, Hirata, K, Yamamoto, M, Nureki, O, Tono, K, Nango, E, Iwata, S, Shirouzu, M. | Deposit date: | 2020-01-10 | Release date: | 2020-11-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Isoprenoid-chained lipid EROCOC 17+4 : a new matrix for membrane protein crystallization and a crystal delivery medium in serial femtosecond crystallography. Sci Rep, 10, 2020
|
|
8C0F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c0f by Molmil](/molmil-images/mine/8c0f) | Tubulin-PTC596 complex | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-fluoranyl-2-(6-fluoranyl-2-methyl-benzimidazol-1-yl)-~{N}4-[4-(trifluoromethyl)phenyl]pyrimidine-4,6-diamine, ... | Authors: | Prota, A.E, Muehlethaler, T, Weetall, M, Steinmetz, M.O. | Deposit date: | 2022-12-16 | Release date: | 2022-12-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1005 Å) | Cite: | Preclinical and Early Clinical Development of PTC596, a Novel Small-Molecule Tubulin-Binding Agent Mol Cancer Ther, 20, 2021
|
|
7Z0Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z0z by Molmil](/molmil-images/mine/7z0z) | Abortive infection DNA polymerase AbiK from Lactococcus lactis, Y44F variant | Descriptor: | AbiK | Authors: | Figiel, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W, Nowotny, M. | Deposit date: | 2022-02-24 | Release date: | 2022-09-07 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases. Nucleic Acids Res., 50, 2022
|
|
4MNB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mnb by Molmil](/molmil-images/mine/4mnb) | Crystal Structure of a complex between the marine anticancer drug Variolin B and DNA | Descriptor: | 5'-D(*CP*GP*TP*AP*CP*G)-3', 9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol, COBALT (II) ION, ... | Authors: | Canals, A, Arribas-Bosacoma, R, Alvarez, M, Albericio, F, Aymami, J, Coll, M. | Deposit date: | 2013-09-10 | Release date: | 2015-03-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Intercalative DNA binding of the marine anticancer drug variolin B. Sci Rep, 7, 2017
|
|
8BYP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8byp by Molmil](/molmil-images/mine/8byp) | |
4ML3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ml3 by Molmil](/molmil-images/mine/4ml3) | X-ray structure of ComE D58A REC domain from Streptococcus pneumoniae | Descriptor: | Response regulator | Authors: | Boudes, M, Sanchez, D, Durand, D, Graille, M, van Tilbeurgh, H, Quevillon-Cheruel, S. | Deposit date: | 2013-09-06 | Release date: | 2014-02-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structural insights into the dimerization of the response regulator ComE from Streptococcus pneumoniae. Nucleic Acids Res., 42, 2014
|
|
4MJM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mjm by Molmil](/molmil-images/mine/4mjm) | Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Short Internal Deletion of CBS Domain from Bacillus anthracis str. Ames | Descriptor: | 1,2-ETHANEDIOL, Inosine-5'-monophosphate dehydrogenase | Authors: | Kim, Y, Makowska-Grzyska, M, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-09-03 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2544 Å) | Cite: | Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Short Internal Deletion of CBS Domain from Bacillus anthracis str. Ames To be Published, 2013
|
|
4MO1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mo1 by Molmil](/molmil-images/mine/4mo1) | Crystal structure of antitermination protein Q from bacteriophage lambda. Northeast Structural Genomics Consortium target OR18A. | Descriptor: | Antitermination protein Q, BROMIDE ION, CHLORIDE ION, ... | Authors: | Vorobiev, S, Su, M, Nickels, B, Seetharaman, J, Sahdev, S, Xiao, R, Kogan, S, Maglaqui, M, Wang, D, Everett, J.K, Acton, T.B, Ebright, R.H, Montelione, G.T, Hunt, J, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2013-09-11 | Release date: | 2013-09-25 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | Crystal structure of antitermination protein Q from bacteriophage lambda. To be Published
|
|
4MU6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mu6 by Molmil](/molmil-images/mine/4mu6) | |
8C5Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c5y by Molmil](/molmil-images/mine/8c5y) | RPA tetrameric supercomplex from Pyrococcus abyssi | Descriptor: | RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ... | Authors: | Madru, C, Martinez-Carranza, M, Legrand, P, Sauguet, L. | Deposit date: | 2023-01-10 | Release date: | 2023-05-03 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | DNA-binding mechanism and evolution of replication protein A. Nat Commun, 14, 2023
|
|
4MSU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4msu by Molmil](/molmil-images/mine/4msu) | Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate | Descriptor: | 1,1,1,3,3,3-hexafluoro-2-{4-[4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... | Authors: | Ashton, K.S, Andrews, K.L, Bryan, M.C, Chen, J, Chen, K, Chen, M, Chmait, S, Croghan, M, Cupples, R, Fotsch, C, Helmering, J, Jordan, S.R, Kurzeja, R.J, Michelsen, K, Pennington, L.D, Poon, S.F, Sivits, G, Van, G, Vonderfecht, S.L, Wahl, R.C, Zhang, J, Lloyd, D.J, Hale, C, St Jean, D.J. | Deposit date: | 2013-09-18 | Release date: | 2014-03-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept. J.Med.Chem., 57, 2014
|
|