5IPK
Structure of the R432A variant of Adeno-associated virus type 2 VLP
This is a non-PDB format compatible entry.
Summary for 5IPK
Entry DOI | 10.2210/pdb5ipk/pdb |
Related | 5IPI |
EMDB information | 8099 8100 |
Descriptor | Capsid protein VP1 (1 entity in total) |
Functional Keywords | adeno-associated virus, r432a, gene therapy, icosahedral, dependoparvovirus, virus like particle |
Biological source | Adeno-associated virus - 2 (AAV-2) |
Total number of polymer chains | 60 |
Total formula weight | 4916714.04 |
Authors | Drouin, L.M.,Lins, B.,Janssen, M.E.,Bennet, A.,Chipman, P.,McKenna, R.,Chen, W.,Muzyczka, N.,Cardone, G.,Baker, T.S.,Agbandje-McKenna, M. (deposition date: 2016-03-09, release date: 2016-07-20, Last modification date: 2024-03-06) |
Primary citation | Drouin, L.M.,Lins, B.,Janssen, M.,Bennett, A.,Chipman, P.,McKenna, R.,Chen, W.,Muzyczka, N.,Cardone, G.,Baker, T.S.,Agbandje-McKenna, M. Cryo-electron Microscopy Reconstruction and Stability Studies of the Wild Type and the R432A Variant of Adeno-associated Virus Type 2 Reveal that Capsid Structural Stability Is a Major Factor in Genome Packaging. J.Virol., 90:8542-8551, 2016 Cited by PubMed: 27440903DOI: 10.1128/JVI.00575-16 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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