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3FN0
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BU of 3fn0 by Molmil
Crystal structure of HIV-1 neutralizing human Fab Z13e1 in complex with a 12-residue peptide containing the Z13e1 epitope on gp41
Descriptor: Envelope polyprotein gp160, Fab Z13e1
Authors:Pejchal, R, Wilson, I.A, Zwick, M.B.
Deposit date:2008-12-22
Release date:2009-06-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies.
J.Virol., 83, 2009
3FO9
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BU of 3fo9 by Molmil
Crystal structure of aldolase antibody 33F12 Fab' in complex with hapten 1,3-diketone
Descriptor: 5-{[4-(5-methyl-3-oxohex-4-en-1-yl)phenyl]amino}-5-oxopentanoic acid, Immunoglobulin IGG2A - heavy chain, Immunoglobulin IGG2A - light chain
Authors:Zhu, X, Wilson, I.A.
Deposit date:2008-12-29
Release date:2009-12-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Direct observation of an enamine intermediate in amine catalysis
J.Am.Chem.Soc., 131, 2009
3GBN
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BU of 3gbn by Molmil
Crystal Structure of Fab CR6261 in Complex with the 1918 H1N1 influenza virus hemagglutinin
Descriptor: 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ekiert, D.C, Elsliger, M.A, Wilson, I.A.
Deposit date:2009-02-20
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antibody recognition of a highly conserved influenza virus epitope.
Science, 324, 2009
3GMN
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BU of 3gmn by Molmil
Structure of mouse CD1d in complex with C10Ph
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
Authors:Schiefner, A, Wilson, I.A.
Deposit date:2009-03-14
Release date:2009-11-10
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
3IMR
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BU of 3imr by Molmil
Transthyretin in complex with (E)-2,6-dibromo-4-(2,6-dichlorostyryl)phenol
Descriptor: 2,6-dibromo-4-[(E)-2-(2,6-dichlorophenyl)ethenyl]phenol, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2009-08-11
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
1VAD
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BU of 1vad by Molmil
MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND YEAST ALPHA-GLUCOSIDASE
Descriptor: BETA-2 MICROGLOBULIN, MHC CLASS I H-2KB HEAVY CHAIN, YEAST ALPHA-GLUCOSIDASE
Authors:Fremont, D.H, Wilson, I.A.
Deposit date:1994-11-01
Release date:1996-06-20
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove.
Proc.Natl.Acad.Sci.USA, 92, 1995
3GBM
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BU of 3gbm by Molmil
Crystal Structure of Fab CR6261 in Complex with a H5N1 influenza virus hemagglutinin.
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ekiert, D.C, Elsliger, M.A, Wilson, I.A.
Deposit date:2009-02-20
Release date:2009-03-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Antibody recognition of a highly conserved influenza virus epitope.
Science, 324, 2009
3IMW
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BU of 3imw by Molmil
Transthyretin in complex with (E)-2,6-dibromo-4-(2,6-dimethoxystyryl)aniline
Descriptor: 2,6-dibromo-4-[(E)-2-(2,6-dimethoxyphenyl)ethenyl]aniline, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2009-08-11
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
3IMS
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BU of 3ims by Molmil
Transthyretin in complex with 2,6-dibromo-4-(2,6-dichlorophenethyl)phenol
Descriptor: 2,6-dibromo-4-[2-(2,6-dichlorophenyl)ethyl]phenol, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2009-08-11
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
3FO2
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BU of 3fo2 by Molmil
Crystal structure of hapten complex of catalytic elimination antibody 13G5 (Glu(L39)Gln mutant)
Descriptor: 5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID, Catalytic antibody Fab 13G5 IgG2b heavy chain chimera, Catalytic antibody Fab 13G5 kappa light chain chimera
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2008-12-27
Release date:2009-11-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.
Proc.Natl.Acad.Sci.USA, 106, 2009
3FO0
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BU of 3fo0 by Molmil
Crystal structure of hapten complex of catalytic elimination antibody 13G5 (wild-type)
Descriptor: 5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID, Catalytic antibody Fab 13G5 IgG2b heavy chain chimera, Catalytic antibody Fab 13G5 kappa light chain chimera, ...
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2008-12-27
Release date:2009-11-10
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.
Proc.Natl.Acad.Sci.USA, 106, 2009
3GML
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BU of 3gml by Molmil
Structure of mouse CD1d in complex with C6Ph
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
Authors:Schiefner, A, Wilson, I.A.
Deposit date:2009-03-14
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
3GMP
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BU of 3gmp by Molmil
Structure of mouse CD1d in complex with PBS-25
Descriptor: (2S,3S,4R)-N-OCTANOYL-1-[(ALPHA-D-GALACTOPYRANOSYL)OXY]-2-AMINO-OCTADECANE-3,4-DIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schiefner, A, Wilson, I.A.
Deposit date:2009-03-14
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
3GMR
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BU of 3gmr by Molmil
Structure of mouse CD1d in complex with C8Ph, different space group
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
Authors:Schiefner, A, Wilson, I.A.
Deposit date:2009-03-14
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
3GMM
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BU of 3gmm by Molmil
Structure of mouse CD1d in complex with C8Ph
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
Authors:Schiefner, A, Wilson, I.A.
Deposit date:2009-03-14
Release date:2009-11-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
3GQ2
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BU of 3gq2 by Molmil
Crystal Structure of the Dimer of the p115 Tether Globular Head Domain
Descriptor: General vesicular transport factor p115
Authors:An, Y, Elsliger, M.A, Wilson, I.A.
Deposit date:2009-03-23
Release date:2009-11-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural and functional analysis of the globular head domain of p115 provides insight into membrane tethering.
J.Mol.Biol., 391, 2009
3HJ0
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BU of 3hj0 by Molmil
Transthyretin in complex with a covalent small molecule kinetic stabilizer
Descriptor: 4-fluorophenyl 3-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzoate, Transthyretin
Authors:Connelly, S, Wilson, I.A, Kelly, J.W.
Deposit date:2009-05-20
Release date:2009-12-22
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma.
Nat.Chem.Biol., 6, 2010
3FO1
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BU of 3fo1 by Molmil
Crystal structure of hapten complex of catalytic elimination antibody 13G5 (Glu(L39)Ala mutant)
Descriptor: 5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID, Catalytic antibody Fab 13G5 IgG2b heavy chain chimera, Catalytic antibody Fab 13G5 kappa light chain chimera
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2008-12-27
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.
Proc.Natl.Acad.Sci.USA, 106, 2009
3GMO
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BU of 3gmo by Molmil
Structure of mouse CD1d in complex with C8PhF
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8-(4-fluorophenyl)-N-{(1S,2S,3R)-1-[(alpha-D-galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl}octanamide, ...
Authors:Schiefner, A, Wilson, I.A.
Deposit date:2009-03-14
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
3IMV
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BU of 3imv by Molmil
Transthyretin in complex with (E)-4-(4-aminostyryl)-2,6-dibromoaniline
Descriptor: 4-[(E)-2-(4-aminophenyl)ethenyl]-2,6-dibromoaniline, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2009-08-11
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
3IMU
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BU of 3imu by Molmil
Transthyretin in complex with (E)-4-(3-aminostyryl)-2,6-dibromoaniline
Descriptor: 4-[(E)-2-(3-aminophenyl)ethenyl]-2,6-dibromoaniline, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2009-08-11
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
3J5M
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BU of 3j5m by Molmil
Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs
Descriptor: BG505 SOSIP gp120, BG505 SOSIP gp41, PGV04 heavy chain, ...
Authors:Lyumkis, D, Julien, J.-P, Wilson, I.A, Ward, A.B.
Deposit date:2013-10-26
Release date:2013-11-13
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer.
Science, 342, 2013
8F0I
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BU of 8f0i by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody COVA309-22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA309-22 heavy chain, COVA309-22 light chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2022-11-03
Release date:2023-09-13
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Broad SARS-CoV-2 neutralization by monoclonal and bispecific antibodies derived from a Gamma-infected individual.
Iscience, 26, 2023
1IAO
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BU of 1iao by Molmil
CLASS II MHC I-AD IN COMPLEX WITH OVALBUMIN PEPTIDE 323-339
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-AD
Authors:Scott, C.A, Peterson, P.A, Teyton, L, Wilson, I.A.
Deposit date:1998-03-13
Release date:1998-11-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues.
Immunity, 8, 1998
1FRG
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BU of 1frg by Molmil
CRYSTAL STRUCTURE, SEQUENCE, AND EPITOPE MAPPING OF A PEPTIDE COMPLEX OF AN ANTI-INFLUENZA HA PEPTIDE ANTIBODY FAB 26(SLASH)9: FINE-TUNING ANTIBODY SPECIFICITY
Descriptor: IGG2A 26/9 FAB (HEAVY CHAIN), IGG2A 26/9 FAB (LIGHT CHAIN), INFLUENZA HEMAGGLUTININ HA1 (STRAIN X47) (RESIDUES 101 - 108)
Authors:Churchill, M.E.A, Wilson, I.A.
Deposit date:1994-01-17
Release date:1994-05-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a peptide complex of anti-influenza peptide antibody Fab 26/9. Comparison of two different antibodies bound to the same peptide antigen.
J.Mol.Biol., 241, 1994

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