1DKQ
 
 | | CRYSTAL STRUCTURE OF PHYTATE COMPLEX ESCHERICHIA COLI PHYTASE AT PH 5.0. PHYTATE IS BOUND WITH ITS 3-PHOSPHATE IN THE ACTIVE SITE. HG2+ CATION ACTS AS AN INTERMOLECULAR BRIDGE | | Descriptor: | INOSITOL HEXAKISPHOSPHATE, MERCURY (II) ION, PHYTASE | | Authors: | Lim, D, Golovan, S, Forsberg, C.W, Jia, Z. | | Deposit date: | 1999-12-08 | | Release date: | 2000-08-03 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Crystal structures of Escherichia coli phytase and its complex with phytate.
Nat.Struct.Biol., 7, 2000
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8QW6
 | | Crystal Structure of compound 3 in complex with KRAS G12V C118S GDP and pVHL:ElonginC:ElonginB | | Descriptor: | (2S,4R)-1-[(2S)-2-[6-[(3S)-4-[4-[5-[(4S)-2-azanyl-3-cyano-4-methyl-6,7-dihydro-5H-1-benzothiophen-4-yl]-1,2,4-oxadiazol-3-yl]pyrimidin-2-yl]-3-methyl-1,4-diazepan-1-yl]hexanoylamino]-3,3-dimethyl-butanoyl]-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | | Authors: | Zollman, D, Farnaby, W, Ciulli, A. | | Deposit date: | 2023-10-18 | | Release date: | 2023-12-06 | | Last modified: | 2024-10-02 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Targeting cancer with small-molecule pan-KRAS degraders.
Science, 385, 2024
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6B9W
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2XHJ
 | | Circular permutation provides an evolutionary link between two families of calcium-dependent carbohydrate binding modules. SeMet form of vCBM60. | | Descriptor: | CALCIUM ION, CALCIUM-DEPENDENT CARBOHYDRATE BINDING MODULE | | Authors: | Montanier, C, Flint, J.E, Bolam, D.N, Xie, H, Liu, Z, Rogowski, A, Weiner, D, Ratnaparkhe, S, Nurizzo, D, Roberts, S.M, Turkenburg, J.P, Davies, G.J, Gilbert, H.J. | | Deposit date: | 2010-06-16 | | Release date: | 2010-07-21 | | Last modified: | 2019-05-08 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-Dependent Carbohydrate Binding Modules
J.Biol.Chem., 285, 2010
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6BAM
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1DKF
 | | CRYSTAL STRUCTURE OF A HETERODIMERIC COMPLEX OF RAR AND RXR LIGAND-BINDING DOMAINS | | Descriptor: | 4-[(4,4-DIMETHYL-1,2,3,4-TETRAHYDRO-[1,2']BINAPTHALENYL-7-CARBONYL)-AMINO]-BENZOIC ACID, OLEIC ACID, PROTEIN (RETINOIC ACID RECEPTOR-ALPHA), ... | | Authors: | Bourguet, W, Vivat, V, Wurtz, J.M, Chambon, P, Gronemeyer, H, Moras, D, Structural Proteomics in Europe (SPINE) | | Deposit date: | 1999-12-07 | | Release date: | 2000-04-19 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains.
Mol.Cell, 5, 2000
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1D9O
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6BMB
 | | Crystal structure of Arabidopsis Dehydroquinate dehydratase-shikimate dehydrogenase (T381G mutant) in complex with tartrate and shikimate | | Descriptor: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic, ... | | Authors: | Christendat, D, Peek, J. | | Deposit date: | 2017-11-14 | | Release date: | 2017-12-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.077 Å) | | Cite: | Structural and biochemical approaches uncover multiple evolutionary trajectories of plant quinate dehydrogenases.
Plant J., 2018
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2XRA
 | | crystal structure of the HK20 Fab in complex with a gp41 mimetic 5- Helix | | Descriptor: | HK20, HUMAN MONOCLONAL ANTIBODY HEAVY CHAIN, HUMAN MONOCLONAL ANTIBODY LIGHT CHAIN, ... | | Authors: | Sabin, C, Corti, D, Buzon, V, Seaman, M.S, Lutje Hulsik, D, Hinz, A, Vanzetta, F, Agatic, G, Silacci, C, Langedijk, J.P.M, Mainetti, L, Scarlatti, G, Sallusto, F, Weiss, R, Lanzavecchia, A, Weissenhorn, W. | | Deposit date: | 2010-09-13 | | Release date: | 2010-12-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure and size-dependent neutralization properties of HK20, a human monoclonal antibody binding to the highly conserved heptad repeat 1 of gp41.
PLoS Pathog., 6, 2010
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1DKL
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1DFF
 | | PEPTIDE DEFORMYLASE | | Descriptor: | PEPTIDE DEFORMYLASE, ZINC ION | | Authors: | Chan, M.K, Gong, W, Rajagopalan, P.T.R, Hao, B, Tsai, C.M, Pei, D. | | Deposit date: | 1997-08-19 | | Release date: | 1998-09-02 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.88 Å) | | Cite: | Crystal structure of the Escherichia coli peptide deformylase.
Biochemistry, 36, 1997
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1M30
 | | Solution structure of N-terminal SH3 domain from oncogene protein c-Crk | | Descriptor: | Proto-oncogene C-crk | | Authors: | Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D. | | Deposit date: | 2002-06-26 | | Release date: | 2003-08-05 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain
To be Published
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1M3C
 | | Solution structure of a circular form of the N-terminal SH3 domain (E132C, E133G, R191G mutant) from oncogene protein c-Crk | | Descriptor: | Proto-oncogene C-crk | | Authors: | Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D. | | Deposit date: | 2002-06-27 | | Release date: | 2003-08-05 | | Last modified: | 2021-10-27 | | Method: | SOLUTION NMR | | Cite: | Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain
To be Published
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1DKE
 | | NI BETA HEME HUMAN HEMOGLOBIN | | Descriptor: | HEMOGLOBIN: ALPHA CHAIN, HEMOGLOBIN: BETA CHAIN, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Bruno, S, Bettatti, S, Mozzarelli, A, Bolognesi, M, Deriu, D, Rosano, C, Tsuneshige, A, Yonetani, T, Henry, E.R. | | Deposit date: | 1999-12-07 | | Release date: | 2000-05-23 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Oxygen binding by alpha(Fe2+)2beta(Ni2+)2 hemoglobin crystals.
Protein Sci., 9, 2000
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6BMQ
 | | Crystal structure of Arabidopsis Dehydroquinate dehydratase-shikimate dehydrogenase (T381G mutant) in complex with tartrate and shikimate | | Descriptor: | (1S,3R,4S,5R)-1,3,4,5-tetrahydroxycyclohexanecarboxylic acid, Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic, ... | | Authors: | Christendat, D, Peek, J. | | Deposit date: | 2017-11-15 | | Release date: | 2018-09-26 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.077 Å) | | Cite: | Structural and biochemical approaches uncover multiple evolutionary trajectories of plant quinate dehydrogenases.
Plant J., 2018
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1P83
 | | NMR STRUCTURE OF 1-25 FRAGMENT OF MYCOBACTERIUM TUBERCULOSIS CPN10 | | Descriptor: | 10 kDa chaperonin | | Authors: | Ciutti, A, Spiga, O, Giannozzi, E, Scarselli, M, Di Maro, D, Calamandrei, D, Niccolai, N, Bernini, A. | | Deposit date: | 2003-05-06 | | Release date: | 2003-05-27 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of 1-25 fragment of Cpn10 from Mycobacterium Tuberculosis
To be Published
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3DHB
 | | 1.4 Angstrom Structure of N-Acyl Homoserine Lactone Hydrolase with the Product N-Hexanoyl-L-Homoserine Bound at The Catalytic Metal Center | | Descriptor: | GLYCEROL, N-Acyl Homoserine Lactone Hydrolase, N-hexanoyl-L-homoserine, ... | | Authors: | Liu, D, Momb, J, Thomas, P.W, Moulin, A, Petsko, G.A, Fast, W, Ringe, D. | | Deposit date: | 2008-06-17 | | Release date: | 2008-07-29 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures.
Biochemistry, 47, 2008
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6BNJ
 | | Human hypoxanthine guanine phosphoribosyltransferase in complex with [3R,4R]-4-guanin-9-yl-3-((R)-2-hydroxy-2-phosphonoethyl)oxy-1-N-(phosphonopropionyl)pyrrolidine | | Descriptor: | (3-{(3R,4R)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-[(2R)-2-hydroxy-2-phosphonoethoxy]pyrrolidin-1-yl}-3-oxopropy l)phosphonic acid, Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION | | Authors: | Keough, D.T, Rejman, D, Guddat, L.W. | | Deposit date: | 2017-11-16 | | Release date: | 2017-12-06 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.909 Å) | | Cite: | Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics.
ACS Chem. Biol., 13, 2018
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2HG7
 | | Solution NMR structure of Phage-like element PBSX protein xkdW, Northeast Structural Genomics Consortium Target SR355 | | Descriptor: | Phage-like element PBSX protein xkdW | | Authors: | Liu, G, Parish, D, Xu, D, Atreya, H, Sukumaran, D, Ho, C.K, Jiang, M, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M, Swapna, G.V, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-06-26 | | Release date: | 2006-08-22 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of Phage-like element PBSX protein xkdW, Northeast Structural Genomics Consortium Target SR355
TO BE PUBLISHED
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1DC7
 | | STRUCTURE OF A TRANSIENTLY PHOSPHORYLATED "SWITCH" IN BACTERIAL SIGNAL TRANSDUCTION | | Descriptor: | NITROGEN REGULATION PROTEIN | | Authors: | Kern, D, Volkman, B.F, Luginbuhl, P, Nohaile, M.J, Kustu, S, Wemmer, D.E. | | Deposit date: | 1999-11-04 | | Release date: | 2000-01-05 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of a transiently phosphorylated switch in bacterial signal transduction.
Nature, 402, 1999
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2X2B
 | | Crystal structure of malonyl-ACP (acyl carrier protein) from Bacillus subtilis | | Descriptor: | 3-{[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-3-oxopropanoic acid, ACYL CARRIER PROTEIN, PLATINUM (II) ION | | Authors: | Bellinzoni, M, Martinez, M.A, DeMendoza, D, Alzari, P.M. | | Deposit date: | 2010-01-12 | | Release date: | 2010-03-16 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | A Novel Role of Malonyl-Acp in Lipid Homeostasis.
Biochemistry, 49, 2010
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1DIS
 | | DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE | | Descriptor: | BRODIMOPRIM-4,6-DICARBOXYLATE, DIHYDROFOLATE REDUCTASE | | Authors: | Morgan, W.D, Birdsall, B, Polshakov, V.I, Sali, D, Kompis, I, Feeney, J. | | Deposit date: | 1995-08-01 | | Release date: | 1995-11-14 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase.
Biochemistry, 34, 1995
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1DKO
 | | CRYSTAL STRUCTURE OF TUNGSTATE COMPLEX OF ESCHERICHIA COLI PHYTASE AT PH 6.6 WITH TUNGSTATE BOUND AT THE ACTIVE SITE AND WITH HG2+ CATION ACTING AS AN INTERMOLECULAR BRIDGE | | Descriptor: | MERCURY (II) ION, PHYTASE, TUNGSTATE(VI)ION | | Authors: | Lim, D, Golovan, S, Forsberg, C.W, Jia, Z. | | Deposit date: | 1999-12-08 | | Release date: | 2000-08-03 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Crystal structures of Escherichia coli phytase and its complex with phytate.
Nat.Struct.Biol., 7, 2000
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1AB2
 | | THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE SRC HOMOLOGY 2 DOMAIN OF C-ABL | | Descriptor: | C-ABL TYROSINE KINASE SH2 DOMAIN | | Authors: | Overduin, M, Rios, C.B, Mayer, B.J, Baltimore, D, Cowburn, D. | | Deposit date: | 1993-07-19 | | Release date: | 1994-01-31 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional solution structure of the src homology 2 domain of c-abl.
Cell(Cambridge,Mass.), 70, 1992
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5MI3
 | | Structure of phosphorylated translation elongation factor EF-Tu from E. coli | | Descriptor: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | Authors: | Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A. | | Deposit date: | 2016-11-27 | | Release date: | 2017-12-20 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
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