6ZGU

Crystal structure of a MFS transporter with bound 3-(2-methylphenyl)propanoic acid at 2.41 Angstroem resolution

Summary for 6ZGU

• Entry DOI: 10.2210/pdb6zgu/pdb
• Descriptor: L-lactate transporter, 3-(2-methylphenyl)propanoic acid (3 entities in total)
• Functional Keywords: l-lactate transporter, monocarboxylate transporter, slc16 family, membrane protein
• Biological source: Syntrophobacter fumaroxidans MPOB
• Total number of polymer chains: 2
• Total formula weight: 89927.89

Authors

Kalbermatter, D.,Bosshart, P.,Bonetti, S.,Fotiadis, D. (deposition date: 2020-06-19, release date: 2021-10-20, Last modification date: 2024-01-24)

• Primary citation: Bosshart, P.D.,Kalbermatter, D.,Bonetti, S.,Fotiadis, D.; The making of a potent L-lactate transport inhibitor; Commun Chem, 4:128-, 2021; DOI: 10.1038/s42004-021-00564-5

Experimental method

X-RAY DIFFRACTION (2.18 Å)