8PSX
 
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8PT6
 
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8PSZ
 
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2C6S
 
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8QZ8
 
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5AMQ
 
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5AMR
 
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2I4L
 
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2I4N
 
 | Rhodopseudomonas palustris prolyl-tRNA synthetase in complex with CysAMS | Descriptor: | 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE, Proline-tRNA ligase | Authors: | Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S. | Deposit date: | 2006-08-22 | Release date: | 2006-10-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain. Structure, 14, 2006
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2I4M
 
 | Rhodopseudomonas palustris prolyl-tRNA synthetase in complex with ProAMS | Descriptor: | '5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE, Proline-tRNA ligase | Authors: | Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S. | Deposit date: | 2006-08-22 | Release date: | 2006-10-24 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain. Structure, 14, 2006
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1H7Z
 
 | Adenovirus Ad3 fibre head | Descriptor: | ADENOVIRUS FIBRE PROTEIN, SULFATE ION | Authors: | Durmort, C, Stehlin, C, Schoehn, G, Mitraki, A, Drouet, E, Cusack, S, Burmeister, W.P. | Deposit date: | 2001-01-21 | Release date: | 2001-07-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the Fiber Head of Ad3, a Non-Car-Binding Serotype of Adenovirus Virology, 285, 2001
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1H6K
 
 | nuclear Cap Binding Complex | Descriptor: | 20 KDA NUCLEAR CAP BINDING PROTEIN, CBP80 | Authors: | Mazza, C, Ohno, M, Segref, A, Mattaj, I.W, Cusack, S. | Deposit date: | 2001-06-18 | Release date: | 2001-09-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the Human Nuclear CAP Binding Complex Mol.Cell, 8, 2001
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2J3M
 
 | PROLYL-TRNA SYNTHETASE FROM ENTEROCOCCUS FAECALIS COMPLEXED WITH ATP, manganese and prolinol | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PROLYL-TRNA SYNTHETASE, ... | Authors: | Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S. | Deposit date: | 2006-08-22 | Release date: | 2006-10-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a Cis-Editing Domain. Structure, 14, 2006
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2J3L
 
 | Prolyl-tRNA synthetase from Enterococcus faecalis complexed with a prolyl-adenylate analogue ('5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE) | Descriptor: | '5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE, PROLYL-TRNA SYNTHETASE, SULFATE ION | Authors: | Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S. | Deposit date: | 2006-08-22 | Release date: | 2006-10-11 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a Cis-Editing Domain. Structure, 14, 2006
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2J2J
 
 | Canine adenovirus fibre head at 1.5 A resolution | Descriptor: | FIBER PROTEIN | Authors: | Seiradake, E, Lortat-Jacob, H, Billet, O, Kremer, E.J, Cusack, S. | Deposit date: | 2006-08-16 | Release date: | 2006-09-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor. J.Biol.Chem., 281, 2006
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2J1K
 
 | CAV-2 fibre head in complex with CAR D1 | Descriptor: | COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR, FIBER PROTEIN | Authors: | Seiradake, E, Lortat-Jacob, H, Billet, O, Kremer, E.J, Cusack, S. | Deposit date: | 2006-08-14 | Release date: | 2006-09-05 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor. J.Biol.Chem., 281, 2006
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5OMW
 
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5ONH
 
 | Quaternary complex of wild type E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation | Descriptor: | 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, 5'-O-(L-leucylsulfamoyl)adenosine, L-leucyl-tRNA(Leu), ... | Authors: | Palencia, A, Cusack, S. | Deposit date: | 2017-08-03 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase. J. Mol. Biol., 430, 2018
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5ON2
 
 | Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation | Descriptor: | 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ... | Authors: | Palencia, A, Cusack, S. | Deposit date: | 2017-08-02 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase. J. Mol. Biol., 430, 2018
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5ON3
 
 | Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of leucine in the aminoacylation conformation | Descriptor: | (2~{S})-~{N}-[(2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-oxidanyl-oxolan-3-yl]-2-azanyl-4-methyl-pentanamide, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ... | Authors: | Palencia, A, Cusack, S. | Deposit date: | 2017-08-02 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase. J. Mol. Biol., 430, 2018
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2IYK
 
 | Crystal structure of the UPF2-interacting domain of nonsense mediated mRNA decay factor UPF1 | Descriptor: | REGULATOR OF NONSENSE TRANSCRIPTS 1, ZINC ION | Authors: | Kadlec, J, Guilligay, D, Ravelli, R.B, Cusack, S. | Deposit date: | 2006-07-18 | Release date: | 2006-08-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal Structure of the Upf2-Interacting Domain of Nonsense-Mediated Mrna Decay Factor Upf1. RNA, 12, 2006
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2J12
 
 | Ad37 fibre head in complex with CAR D1 | Descriptor: | CALCIUM ION, COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR, FIBER PROTEIN | Authors: | Seiradake, E, Lortat-Jacob, H, Billet, O, Kremer, E.J, Cusack, S. | Deposit date: | 2006-08-08 | Release date: | 2006-08-29 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor. J.Biol.Chem., 281, 2006
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4CB7
 
 | Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 8e) | Descriptor: | 5-[2-(2-azanyl-7-methyl-6-oxidanylidene-1H-purin-9-ium-9-yl)ethanoyl]-2-oxidanyl-benzoic acid, GLYCEROL, POLYMERASE BASIC SUBUNIT 2 | Authors: | Pautus, S, Sehr, P, Lewis, J, Fortune, A, Wolkerstorfer, A, Szolar, O, Gulligay, D, Lunardi, T, Decout, J.L, Cusack, S. | Deposit date: | 2013-10-10 | Release date: | 2013-10-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | New 7-Methyl-Guanosine Derivatives Targeting the Influenza Polymerase Pb2 CAP-Binding Domain J.Med.Chem., 56, 2013
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4CB5
 
 | Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 8f) | Descriptor: | 9-N-(3-CARBOXY-4-HYDROXYPHENYL)KETOMETHYL-7-N-METHYLGUANINE, CHLORIDE ION, POLYMERASE BASIC SUBUNIT 2 | Authors: | Pautus, S, Sehr, P, Lewis, J, Fortune, A, Wolkerstorfer, A, Szolar, O, Gulligay, D, Lunardi, T, Decout, J.L, Cusack, S. | Deposit date: | 2013-10-10 | Release date: | 2013-10-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | New 7-Methyl-Guanosine Derivatives Targeting the Influenza Polymerase Pb2 CAP-Binding Domain J.Med.Chem., 56, 2013
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4CB6
 
 | Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 11) | Descriptor: | 2,9-N,N-DI(4-CARBOXYBUTYL)-7-N-METHYLGUANINE, IODIDE ION, POLYMERASE BASIC SUBUNIT 2 | Authors: | Pautus, S, Sehr, P, Lewis, J, Fortune, A, Wolkerstorfer, A, Szolar, O, Gulligay, D, Lunardi, T, Decout, J.L, Cusack, S. | Deposit date: | 2013-10-10 | Release date: | 2013-10-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | New 7-Methyl-Guanosine Derivatives Targeting the Influenza Polymerase Pb2 CAP-Binding Domain J.Med.Chem., 56, 2013
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