8IZ4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8iz4 by Molmil](/molmil-images/mine/8iz4) | Lysophosphatidylserine receptor GPR34-Gi complex | Descriptor: | Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Gong, W, Liu, G, Li, X, Zhang, X. | Deposit date: | 2023-04-06 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Structural mechanisms of ligand binding and signaling in lysophosphatidylserine receptors To Be Published
|
|
7X2H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x2h by Molmil](/molmil-images/mine/7x2h) | |
8K7A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k7a by Molmil](/molmil-images/mine/8k7a) | |
8K4B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k4b by Molmil](/molmil-images/mine/8k4b) | Cryo-EM structure of nucleotide-bound ComA with ZinC ion | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Competence factor transporting ATP-binding protein/permease ComA, ZINC ION | Authors: | Yu, L, Xin, X, Min, L, Feng, H. | Deposit date: | 2023-07-17 | Release date: | 2023-10-11 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis of peptide secretion for Quorum sensing by ComA. Nat Commun, 14, 2023
|
|
8K8K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k8k by Molmil](/molmil-images/mine/8k8k) | Structure of Klebsiella pneumonia ModA | Descriptor: | Molybdate transporter periplasmic protein | Authors: | Zhao, Q, Bartlam, M. | Deposit date: | 2023-07-31 | Release date: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural analysis of molybdate binding protein ModA from Klebsiella pneumoniae. Biochem.Biophys.Res.Commun., 681, 2023
|
|
8KGY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8kgy by Molmil](/molmil-images/mine/8kgy) | Human glutamate dehydrogenase I | Descriptor: | Glutamate dehydrogenase 1, mitochondrial | Authors: | Su, M.-Y. | Deposit date: | 2023-08-20 | Release date: | 2023-10-25 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | Cryo-EM structure of the KLHL22 E3 ligase bound to an oligomeric metabolic enzyme. Structure, 31, 2023
|
|
8K8L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k8l by Molmil](/molmil-images/mine/8k8l) | |
8KHP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8khp by Molmil](/molmil-images/mine/8khp) | CULLIN3-KLHL22-RBX1 E3 ligase | Descriptor: | Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch-like protein 22 | Authors: | Su, M.-Y, Su, M.-Y. | Deposit date: | 2023-08-22 | Release date: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.67 Å) | Cite: | Cryo-EM structure of the KLHL22 E3 ligase bound to an oligomeric metabolic enzyme. Structure, 31, 2023
|
|
7XD2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xd2 by Molmil](/molmil-images/mine/7xd2) | |
8KHR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8khr by Molmil](/molmil-images/mine/8khr) | Cryo-EM structure of EBV gH/gL-gp42 in complex with fab 2C1 | Descriptor: | 2C1 heavy chain, 2C1 light chain, Envelope glycoprotein H, ... | Authors: | Fang, X.Y, Zhao, G.X, Zeng, M.S, Liu, Z. | Deposit date: | 2023-08-22 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Potent human monoclonal antibodies targeting Epstein-Barr virus gp42 reveal vulnerable sites for virus infection. Cell Rep Med, 5, 2024
|
|
8IZF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8izf by Molmil](/molmil-images/mine/8izf) | Cryo-EM structure of the Lac1-Lip1 (Lip1-S74F) complex | Descriptor: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, Ceramide synthase LAC1, Ceramide synthase subunit LIP1 | Authors: | Xie, T, Fang, Q, Gong, X. | Deposit date: | 2023-04-07 | Release date: | 2023-12-13 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Structure and mechanism of a eukaryotic ceramide synthase complex. Embo J., 42, 2023
|
|
8IZD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8izd by Molmil](/molmil-images/mine/8izd) | Cryo-EM structure of the C26-CoA-bound Lac1-Lip1 complex | Descriptor: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, Ceramide synthase LAC1, Ceramide synthase subunit LIP1, ... | Authors: | Xie, T, Fang, Q, Gong, X. | Deposit date: | 2023-04-07 | Release date: | 2023-12-13 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Structure and mechanism of a eukaryotic ceramide synthase complex. Embo J., 42, 2023
|
|
3UUF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3uuf by Molmil](/molmil-images/mine/3uuf) | Crystal structure of mono- and diacylglycerol lipase from Malassezia globosa | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LIP1, secretory lipase (Family 3), ... | Authors: | Xu, T, Xu, J, Hou, S, Liu, J. | Deposit date: | 2011-11-28 | Release date: | 2012-04-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of a mono- and diacylglycerol lipase from Malassezia globosa reveals a novel lid conformation and insights into the substrate specificity. J.Struct.Biol., 178, 2012
|
|
8OOJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ooj by Molmil](/molmil-images/mine/8ooj) | Crystal structure of dCK C4S-S74E mutant in complex with EdC and UDP | Descriptor: | 4-azanyl-1-[(2~{R},4~{S},5~{R})-5-ethynyl-5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]pyrimidin-2-one, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE | Authors: | Saez-Ayala, M, Rebuffet, E, Betzi, S, Morelli, X. | Deposit date: | 2023-04-05 | Release date: | 2023-12-20 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | 4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress. Mol.Cancer Ther., 23, 2024
|
|
3UUE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3uue by Molmil](/molmil-images/mine/3uue) | Crystal structure of mono- and diacylglycerol lipase from Malassezia globosa | Descriptor: | CHLORIDE ION, GLYCEROL, LIP1, ... | Authors: | Xu, T, Xu, J, Hou, S, Liu, J. | Deposit date: | 2011-11-28 | Release date: | 2012-04-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of a mono- and diacylglycerol lipase from Malassezia globosa reveals a novel lid conformation and insights into the substrate specificity. J.Struct.Biol., 178, 2012
|
|
7YHK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yhk by Molmil](/molmil-images/mine/7yhk) | Cryo-EM structure of the HA trimer of A/Beijing/262/1995(H1N1) in complex with neutralizing antibody 12H5 | Descriptor: | 12H5 heavy chain, 12H5 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zheng, Q, Li, S, Li, T, Xue, W, Sun, H. | Deposit date: | 2022-07-13 | Release date: | 2022-08-17 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses. Nat Commun, 13, 2022
|
|
8JIO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jio by Molmil](/molmil-images/mine/8jio) | |
7WI0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wi0 by Molmil](/molmil-images/mine/7wi0) | SARS-CoV-2 Omicron variant spike in complex with three human neutralizing antibodies | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ... | Authors: | Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S. | Deposit date: | 2022-01-01 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron. Cell Rep, 39, 2022
|
|
7WHZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7whz by Molmil](/molmil-images/mine/7whz) | SARS-CoV-2 spike protein in complex with three human neutralizing antibodies | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ... | Authors: | Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S. | Deposit date: | 2022-01-01 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron. Cell Rep, 39, 2022
|
|
5GMT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gmt by Molmil](/molmil-images/mine/5gmt) | |
7WVP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wvp by Molmil](/molmil-images/mine/7wvp) | |
7WVQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wvq by Molmil](/molmil-images/mine/7wvq) | |
7X8O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x8o by Molmil](/molmil-images/mine/7x8o) | NMR Solution Structure of the 2:1 Coptisine-KRAS-G4 Complex | Descriptor: | 6,7-dihydro[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquino[3,2-a]isoquinolin-5-ium, DNA (24-MER) | Authors: | Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y. | Deposit date: | 2022-03-14 | Release date: | 2022-09-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine. Nat Commun, 13, 2022
|
|
7X8N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x8n by Molmil](/molmil-images/mine/7x8n) | NMR Solution Structure of the Wild-type Bulge-containing KRAS-G4 | Descriptor: | DNA (24-mer) | Authors: | Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y. | Deposit date: | 2022-03-14 | Release date: | 2022-09-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine. Nat Commun, 13, 2022
|
|
7X8M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x8m by Molmil](/molmil-images/mine/7x8m) | NMR Solution Structure of the 2:1 Berberine-KRAS-G4 Complex | Descriptor: | BERBERINE, DNA (24-MER) | Authors: | Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y. | Deposit date: | 2022-03-14 | Release date: | 2022-09-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine. Nat Commun, 13, 2022
|
|