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8KHR

Cryo-EM structure of EBV gH/gL-gp42 in complex with fab 2C1

Summary for 8KHR
Entry DOI10.2210/pdb8khr/pdb
EMDB information37249
DescriptorSoluble gp42, 2C1 heavy chain, 2C1 light chain, ... (5 entities in total)
Functional Keywordshuman gammaherpesvirus 4, neutralizing antibody, viral protein/immune system, viral protein-immune system complex
Biological sourceEpstein-Barr virus (strain GD1) (HHV-4, Human herpesvirus 4)
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Total number of polymer chains5
Total formula weight130585.48
Authors
Fang, X.Y.,Zhao, G.X.,Zeng, M.S.,Liu, Z. (deposition date: 2023-08-22, release date: 2024-06-19)
Primary citationZhao, G.X.,Fang, X.Y.,Bu, G.L.,Chen, S.J.,Sun, C.,Li, T.,Xie, C.,Wang, Y.,Li, S.X.,Meng, N.,Feng, G.K.,Zhong, Q.,Kong, X.W.,Liu, Z.,Zeng, M.S.
Potent human monoclonal antibodies targeting Epstein-Barr virus gp42 reveal vulnerable sites for virus infection.
Cell Rep Med, 5:101573-101573, 2024
Cited by
PubMed: 38776874
DOI: 10.1016/j.xcrm.2024.101573
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.25 Å)
Structure validation

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PDB entries from 2024-07-03

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