8KHR

Cryo-EM structure of EBV gH/gL-gp42 in complex with fab 2C1

Summary for 8KHR

• Entry DOI: 10.2210/pdb8khr/pdb
• EMDB information: 37249
• Descriptor: Soluble gp42, 2C1 heavy chain, 2C1 light chain, ... (5 entities in total)
• Functional Keywords: human gammaherpesvirus 4, neutralizing antibody, viral protein/immune system, viral protein-immune system complex
• Biological source: Epstein-Barr virus (strain GD1) (HHV-4, Human herpesvirus 4); More
• Total number of polymer chains: 5
• Total formula weight: 130585.48

Authors

Fang, X.Y.,Zhao, G.X.,Zeng, M.S.,Liu, Z. (deposition date: 2023-08-22, release date: 2024-06-19)

• Primary citation: Zhao, G.X.,Fang, X.Y.,Bu, G.L.,Chen, S.J.,Sun, C.,Li, T.,Xie, C.,Wang, Y.,Li, S.X.,Meng, N.,Feng, G.K.,Zhong, Q.,Kong, X.W.,Liu, Z.,Zeng, M.S.; Potent human monoclonal antibodies targeting Epstein-Barr virus gp42 reveal vulnerable sites for virus infection.; Cell Rep Med, 5:101573-101573, 2024; PubMed: 38776874; DOI: 10.1016/j.xcrm.2024.101573

Experimental method

ELECTRON MICROSCOPY (3.25 Å)