8IZF

Cryo-EM structure of the Lac1-Lip1 (Lip1-S74F) complex

Summary for 8IZF

• Entry DOI: 10.2210/pdb8izf/pdb
• EMDB information: 35863
• Descriptor: Ceramide synthase LAC1, Ceramide synthase subunit LIP1, (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE (3 entities in total)
• Functional Keywords: substrate, complex, transferase
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (baker's yeast); More
• Total number of polymer chains: 4
• Total formula weight: 138746.08

Authors

Xie, T.,Fang, Q.,Gong, X. (deposition date: 2023-04-07, release date: 2023-12-13, Last modification date: 2023-12-20)

• Primary citation: Xie, T.,Fang, Q.,Zhang, Z.,Wang, Y.,Dong, F.,Gong, X.; Structure and mechanism of a eukaryotic ceramide synthase complex.; Embo J., 42:e114889-e114889, 2023; PubMed: 37953642; DOI: 10.15252/embj.2023114889

Experimental method

ELECTRON MICROSCOPY (3.85 Å)