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8FNK
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BU of 8fnk by Molmil
Cryo-EM structure of RNase-untreated RESC-B in trypanosomal RNA editing
Descriptor: RNA-editing substrate-binding complex protein 10 (RESC10), RNA-editing substrate-binding complex protein 11 (RESC11), RNA-editing substrate-binding complex protein 13 (RESC13), ...
Authors:Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
Deposit date:2022-12-27
Release date:2023-07-19
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
4I8B
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BU of 4i8b by Molmil
Crystal Structure of Thioredoxin from Schistosoma Japonicum
Descriptor: Thioredoxin
Authors:Wu, Q, Peng, Y, Zhao, J, Li, X, Fan, X, Zhou, X, Chen, J, Luo, Z, Shi, D.
Deposit date:2012-12-03
Release date:2013-12-04
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Expression, characterization and crystal structure of thioredoxin from Schistosoma japonicum.
Parasitology, 142, 2015
4RDL
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BU of 4rdl by Molmil
Crystal structure of Norovirus Boxer P domain in complex with Lewis y tetrasaccharide
Descriptor: Capsid, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose
Authors:Hao, N, Chen, Y, Xia, M, Liu, W, Tan, M, Jiang, X, Li, X.
Deposit date:2014-09-19
Release date:2015-01-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Crystal structures of GI.8 Boxer virus P dimers in complex with HBGAs, a novel evolutionary path selected by the Lewis epitope.
Protein Cell, 6, 2015
4RDK
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BU of 4rdk by Molmil
Crystal structure of Norovirus Boxer P domain in complex with Lewis b tetrasaccharide
Descriptor: Capsid, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose
Authors:Hao, N, Chen, Y, Xia, M, Liu, W, Tan, M, Jiang, X, Li, X.
Deposit date:2014-09-19
Release date:2015-01-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.629 Å)
Cite:Crystal structures of GI.8 Boxer virus P dimers in complex with HBGAs, a novel evolutionary path selected by the Lewis epitope.
Protein Cell, 6, 2015
4QWQ
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BU of 4qwq by Molmil
Crystal structure of the DNA-binding domain of the response regulator SaeR from Staphylococcus aureus
Descriptor: Response regulator SaeR
Authors:Fan, X, Zhu, Y, Zhang, X, Teng, M, Li, X.
Deposit date:2014-07-17
Release date:2015-08-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structure of the DNA-binding domain of the response regulator SaeR from Staphylococcus aureus.
Acta Crystallogr.,Sect.D, 71, 2015
6XBK
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BU of 6xbk by Molmil
Structure of human SMO-G111C/I496C complex with Gi
Descriptor: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Qi, X, Long, T, Li, X.
Deposit date:2020-06-06
Release date:2020-09-30
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling.
Nat.Chem.Biol., 16, 2020
6XBM
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BU of 6xbm by Molmil
Structure of human SMO-Gi complex with 24(S),25-EC
Descriptor: 17-[3-(3,3-DIMETHYL-OXIRANYL)-1-METHYL-PROPYL]-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYC LOPENTA[A]PHENANTHREN-3-OL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Qi, X, Long, T, Li, X.
Deposit date:2020-06-06
Release date:2020-09-30
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling.
Nat.Chem.Biol., 16, 2020
6XBL
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BU of 6xbl by Molmil
Structure of human SMO-Gi complex with SAG
Descriptor: 3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-{[3-(pyridin-4-yl)phenyl]methyl}-1-benzothiophene-2-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Qi, X, Li, X.
Deposit date:2020-06-06
Release date:2020-09-30
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling.
Nat.Chem.Biol., 16, 2020
6XBJ
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BU of 6xbj by Molmil
Structure of human SMO-D384R complex with Gi
Descriptor: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Qi, X, Long, T, Li, X.
Deposit date:2020-06-06
Release date:2020-09-30
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (3.88 Å)
Cite:Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling.
Nat.Chem.Biol., 16, 2020
6E1H
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BU of 6e1h by Molmil
Structure of 2:1 human Ptch1-Shh-N complex
Descriptor: CALCIUM ION, PALMITIC ACID, Protein patched homolog 1, ...
Authors:Qi, X, Li, X.
Deposit date:2018-07-09
Release date:2018-08-29
Last modified:2023-02-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Two Patched molecules engage distinct sites on Hedgehog yielding a signaling-competent complex.
Science, 362, 2018
8J00
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BU of 8j00 by Molmil
Human KCNQ2-CaM in complex with CBD
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, cannabidiol
Authors:Ma, D, Li, X, Guo, J.
Deposit date:2023-04-09
Release date:2023-11-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8IZY
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BU of 8izy by Molmil
Human KCNQ2-CaM in complex with HN37
Descriptor: Potassium voltage-gated channel subfamily KQT member 2, methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate
Authors:Ma, D, Li, X, Guo, J.
Deposit date:2023-04-09
Release date:2023-11-29
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8J05
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BU of 8j05 by Molmil
Human KCNQ2-CaM complex in the presence of PIP2
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2
Authors:Ma, D, Li, X, Guo, J.
Deposit date:2023-04-09
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8J04
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BU of 8j04 by Molmil
Human KCNQ2-CaM-HN37 complex in the presence of PIP2
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate
Authors:Ma, D, Li, X, Guo, J.
Deposit date:2023-04-09
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8J01
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BU of 8j01 by Molmil
Human KCNQ2-CaM in complex with CBD and PIP2
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ...
Authors:Ma, D, Li, X, Guo, J.
Deposit date:2023-04-09
Release date:2023-12-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8J02
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BU of 8j02 by Molmil
Human KCNQ2(F104A)-CaM-PIP2-CBD complex in state II
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ...
Authors:Ma, D, Li, X, Guo, J.
Deposit date:2023-04-09
Release date:2023-12-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
9AYB
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BU of 9ayb by Molmil
Structure of Apo Sialin S61A mutant
Descriptor: Sialin
Authors:Schmiege, P, Li, X.
Deposit date:2024-03-07
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structure of Apo Sialin S61A mutant
To Be Published
7RR5
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BU of 7rr5 by Molmil
Structure of ribosomal complex bound with Rbg1/Tma46
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ...
Authors:Zeng, F, Li, X, Pires-Alves, M, Chen, X, Hawk, C.W, Jin, H.
Deposit date:2021-08-09
Release date:2021-11-10
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells.
Cell Rep, 37, 2021
3AQQ
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BU of 3aqq by Molmil
Crystal structure of human CRHSP-24
Descriptor: Calcium-regulated heat stable protein 1
Authors:Hou, H, Wang, F, Zhang, W, Wang, D, Li, X, Bartlam, M, Yao, X, Rao, Z.
Deposit date:2010-11-17
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:CRHSP-24 is a novel cargo adaptor trafficking between stress granules and processing bodies
To be Published
118D
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BU of 118d by Molmil
CRYSTAL AND MOLECULAR STRUCTURE OF D(GTGCGCAC): INVESTIGATION OF THE EFFECTS OF BASE SEQUENCE ON THE CONFORMATION OF OCTAMER DUPLEXES
Descriptor: DNA (5'-D(*GP*TP*GP*CP*GP*CP*AP*C)-3')
Authors:Bingman, C.A, Li, X, Zon, G, Sundaralingam, M.
Deposit date:1993-02-11
Release date:1993-02-11
Last modified:2023-03-22
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystal and molecular structure of d(GTGCGCAC): investigation of the effects of base sequence on the conformation of octamer duplexes.
Biochemistry, 31, 1992
6PSL
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BU of 6psl by Molmil
Structure of a N-Me-D-Gln4,D-aza-Thr8,Arg10-teixobactin analogue
Descriptor: CHLORIDE ION, teixobactin analogue
Authors:Nowick, J.S, Yang, H, Pishenko, A, Li, X.
Deposit date:2019-07-12
Release date:2019-11-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design, Synthesis, and Study of Lactam and Ring-Expanded Analogues of Teixobactin.
J.Org.Chem., 85, 2020
5XSG
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BU of 5xsg by Molmil
Ultrahigh resolution structure of FUS (37-42) SYSGYS determined by MicroED
Descriptor: RNA-binding protein FUS
Authors:Luo, F, Gui, X, Zhou, H, Li, D, Li, X, Liu, C.
Deposit date:2017-06-14
Release date:2018-04-04
Last modified:2024-03-27
Method:ELECTRON CRYSTALLOGRAPHY (0.73 Å)
Cite:Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation.
Nat. Struct. Mol. Biol., 25, 2018
1C9W
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BU of 1c9w by Molmil
CHO REDUCTASE WITH NADP+
Descriptor: CHO REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Ye, Q, Li, X, Hyndman, D, Flynn, T.G, Jia, Z.
Deposit date:1999-08-03
Release date:2000-01-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of CHO reductase, a member of the aldo-keto reductase superfamily.
Proteins, 38, 2000
4QPI
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BU of 4qpi by Molmil
Crystal structure of hepatitis A virus
Descriptor: CHLORIDE ION, Capsid protein VP1, Capsid protein VP2, ...
Authors:Wang, X, Ren, J, Gao, Q, Hu, Z, Sun, Y, Li, X, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E.
Deposit date:2014-06-23
Release date:2014-10-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Hepatitis A virus and the origins of picornaviruses.
Nature, 517, 2015
3S5J
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BU of 3s5j by Molmil
2.0A Crystal structure of human phosphoribosyl pyrophosphate synthetase 1
Descriptor: Ribose-phosphate pyrophosphokinase 1, SULFATE ION
Authors:Chen, P, Teng, M, Li, X.
Deposit date:2011-05-23
Release date:2012-05-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations
Plos One, 10, 2015

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