8J04

Human KCNQ2-CaM-HN37 complex in the presence of PIP2

Summary for 8J04

• Entry DOI: 10.2210/pdb8j04/pdb
• EMDB information: 35883
• Descriptor: Potassium voltage-gated channel subfamily KQT member 2, Calmodulin-1, methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate (3 entities in total)
• Functional Keywords: potassium voltage-gated channel, hn37, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 375696.16

Authors

Ma, D.,Li, X.,Guo, J. (deposition date: 2023-04-09, release date: 2023-12-06)

• Primary citation: Ma, D.,Zheng, Y.,Li, X.,Zhou, X.,Yang, Z.,Zhang, Y.,Wang, L.,Zhang, W.,Fang, J.,Zhao, G.,Hou, P.,Nan, F.,Yang, W.,Su, N.,Gao, Z.,Guo, J.; Ligand activation mechanisms of human KCNQ2 channel.; Nat Commun, 14:6632-6632, 2023; PubMed: 37857637; DOI: 10.1038/s41467-023-42416-x

Experimental method

ELECTRON MICROSCOPY (2.7 Å)