8J04
Human KCNQ2-CaM-HN37 complex in the presence of PIP2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D, G (A, B, D, G) | Potassium voltage-gated channel subfamily KQT member 2 | polymer | 656 | 73627.8 | 4 | UniProt (O43526) Pfam (PF00520) Pfam (PF07885) Pfam (PF03520) Pfam (PF16642) | Homo sapiens (human) | KQT-like 2,Neuroblastoma-specific potassium channel subunit alpha KvLQT2,Voltage-gated potassium channel subunit Kv7.2 |
| 2 | C, E, F, H (C, E, F, H) | Calmodulin-1 | polymer | 177 | 19615.4 | 4 | UniProt (P0DP23) Pfam (PF13499) | Homo sapiens (human) | |
| 3 | I, J, K, L, M... (A, B, D, G) | methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate | non-polymer | 340.4 | 8 | Chemie (9MF) |
Sequence modifications
A, B, D, G: 64 - 702 (UniProt: O43526)
C, E, F, H: 1 - 149 (UniProt: P0DP23)
| PDB | External Database | Details |
|---|---|---|
| Met 63 | - | initiating methionine |
| Val 703 | - | expression tag |
| Glu 704 | - | expression tag |
| Gly 705 | - | expression tag |
| Gly 706 | - | expression tag |
| Ser 707 | - | expression tag |
| Ser 708 | - | expression tag |
| Gly 709 | - | expression tag |
| Gly 710 | - | expression tag |
| Trp 711 | - | expression tag |
| Ser 712 | - | expression tag |
| His 713 | - | expression tag |
| Pro 714 | - | expression tag |
| Gln 715 | - | expression tag |
| Phe 716 | - | expression tag |
| Glu 717 | - | expression tag |
| Lys 718 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 150 | - | expression tag |
| Glu 151 | - | expression tag |
| Gly 152 | - | expression tag |
| Gly 153 | - | expression tag |
| Ser 154 | - | expression tag |
| Ser 155 | - | expression tag |
| Gly 156 | - | expression tag |
| Gly 157 | - | expression tag |
| Leu 158 | - | expression tag |
| Val 159 | - | expression tag |
| Pro 160 | - | expression tag |
| Arg 161 | - | expression tag |
| Gly 162 | - | expression tag |
| Ser 163 | - | expression tag |
| Gly 164 | - | expression tag |
| Gly 165 | - | expression tag |
| Ser 166 | - | expression tag |
| Ser 167 | - | expression tag |
| Gly 168 | - | expression tag |
| Gly 169 | - | expression tag |
| His 170 | - | expression tag |
| His 171 | - | expression tag |
| His 172 | - | expression tag |
| His 173 | - | expression tag |
| His 174 | - | expression tag |
| His 175 | - | expression tag |
| His 176 | - | expression tag |
| His 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 372973.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2723.1 | |
| All* | Total formula weight | 375696.2 |
