6XBL
Structure of human SMO-Gi complex with SAG
Summary for 6XBL
Entry DOI | 10.2210/pdb6xbl/pdb |
EMDB information | 22119 |
Descriptor | Smoothened homolog, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total) |
Functional Keywords | gpcr, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 186395.32 |
Authors | |
Primary citation | Qi, X.,Friedberg, L.,De Bose-Boyd, R.,Long, T.,Li, X. Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling. Nat.Chem.Biol., 16:1368-1375, 2020 Cited by PubMed: 32929279DOI: 10.1038/s41589-020-0646-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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