9XZJ

Cryo-EM structure of F-box helicase 1 (FBH1) bound to an SCF ubiquitin ligase complex and a 3-way DNA fork (consensus structure)

Summary for 9XZJ

Entry DOI	10.2210/pdb9xzj/pdb
Related	9XZK 9XZL 9XZM
EMDB information	72358
Descriptor	Cullin-1, MAGNESIUM ION, ZINC ION, ... (11 entities in total)
Functional Keywords	helicase, translocase, fork remodeler, fork reversal, replication fork, dna binding, isomerase-dna complex, isomerase/dna
Biological source	Homo sapiens (human) More
Total number of polymer chains	8
Total formula weight	270794.58
Authors	Mullins, E.A.,Schiltz, C.J.,Eichman, B.F. (deposition date: 2025-08-27, release date: 2026-01-28)
Primary citation	Greer, B.H.,Mendia Garcia, J.,Mullins, E.A.,Peacock, E.M.,Haigh, S.,Schiltz, C.J.,Tsai, M.-S.,Cortez, D.,Moreno-Herrero, F.,Eichman, B.F. F-box helicase 1 reverses replication forks through assembly on the lagging strand template at the fork junction To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.13 Å)

Structure validation